Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.1.4.3 (phospholipase C)
18,461 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein PLC 1685 Mol 1430 Sep 1363 phosphatidylinositol-specific 1299 ATP 1088 phospholipase A2 949 GTP 944 phospholipase D 835 tyrosine kinase 733 endoplasmic reticulum 666 adenylate cyclase 666 adenylyl cyclase 661 thrombin 572 ADP 538 insulin 530 PKC 523 AMP 521 phospholipase 505 phosphoinositide-specific 473 calmodulin 463 bradykinin 420 angiotensin II 368 phosphatidylinositol 3-kinase 348 Phospholipase C 332 membrane-bound 310 ATPase 304 phosphatase 303 epidermal growth factor 278 ERK1 277 PtdIns 276 vasopressin 267 cyclooxygenase 264 collagen 263 GDP 260 glycoprotein 259 muscarinic receptor 254 cytokine 248 protein kinase C inhibitor 247 platelet-derived growth factor 240 lipase 236 p38 233 polypeptide 228 PIP 225 G protein-coupled receptor 223 alkaline phosphatase 222 Rho 217 GTPase 209 ERK 206 mitogen-activated protein 201 Pseudomonas 197 extracellular signal-regulated kinase 195 GTP-binding protein 195 SDS 194 Ins 192 endothelin-1 187 Ang II 185 metabotropic glutamate receptor 184 MAPK 184 pleckstrin 179 phosphodiesterase 174 phosphoinositide 3-kinase 169 protein tyrosine kinase 166 beta 1 159 lipopolysaccharide 157 substance P 155 microsomal 153 MAP kinase 152 gamma2 152 nitric oxide synthase 149 calcium channel 146 bombesin 143 epidermal growth factor receptor 142 membrane protein 138 lipoxygenase 135 PKA 132 MEK 132 Gen 127 neuraminidase 127 5-hydroxytryptamine 125 P2Y2 124 oxytocin 123 cholecystokinin 121 c-fos 119 EGF receptor 116 HEK 112 G-protein-coupled receptor 112 ras 111 threonine 111 PI-PLC 110 PI3K 109 diacylglycerol kinase 109 RhoA 108 tumor necrosis factor 107 AT1 107 APB 106 TCR 105 receptor tyrosine kinase 104 GPI 101 ionotropic 100 TRPC3 99 acetylcholinesterase 96 PH domain 95 myosin light chain 95 NEMO 93 EGF 92 rhodopsin 92 ET-1 91 mast cell 91 chemokine 90 fused 90 GABA 89 cAMP-dependent protein kinase 89 TPA 89 pituitary adenylate cyclase-activating polypeptide 87 NMR 87 GTPase-activating protein 87 parathyroid hormone 87 guanine nucleotide-binding protein 86 P2X 86 p42 86 DAG 85 T cell receptor 84 fibronectin 83 spermatozoa 82 PLCgamma1 82 IgE 80 PLA 80 nerve growth factor 80 IL-8 80 glucagon 79 JNK 78 guanylate cyclase 78 protein phosphatase 78 proximal tubule 78 p44 78 PKC-alpha 77 PDGF 77 muscarinic acetylcholine receptor 76 Thy-1 76 CD4 76 fibrinogen 76 Met 75 lectin 75 olfactory 74 glucosamine 74 mGluR5 74 caspase-3 74 TRP 74 adaptor protein 73 G alpha q 73 IL-2 70 lymphoid 70 somatostatin 69 c-Src 68 LPS 68 IL-6 68 CA1 68 ryanodine receptor 68 osteosarcoma 68 P2Y1 68 more...

Disease pertussis 1399 cancer 416 tumor 383 cholera 251 SDS 194 hypertension 182 neuroblastoma 170 leukemia 149 depression 141 diabetes 137 ATM 111 glioma 111 ischemia 111 Alzheimer's disease 109 carcinoma 93 breast cancer 89 astrocytoma 80 atherosclerosis 80 lymphoma 75 cystic fibrosis 73 osteosarcoma 73 gas gangrene 73 hepatocellular carcinoma 72 cold 70 asthma 61 prostate cancer 58 sepsis 55 Blocking 54 uterus 51 schizophrenia 49 carcinogenesis 49 melanoma 49 infectious diseases 48 pheochromocytoma 47 sepsis 46 MCF 42 PAF 41 tumor growth 38 Mycobacterium 38 adenocarcinoma 38 obesity 37 Infection 35 tumorigenesis 35 squamous cell carcinoma 35 stroke 34 immunodeficiency 33 tuberculosis 33 HIV 33 tumor progression 32 SEM 32 type 2 diabetes 32 enteritis 32 NAME 31 rheumatoid arthritis 30 plaque 30 heart failure 30 paroxysmal nocturnal hemoglobinuria 30 MRS 29 mole 29 erythroleukemia 29 pneumonia 29 glioblastoma 29 mole 29 epilepsy 28 Pituitary 28 Steroids 28 cardiovascular disease 27 acute promyelocytic leukemia 25 tetanus 25 Bordetella 25 lung cancer 25 ovarian cancer 24 essential hypertension 24 colon cancer 23 cytomegalovirus 23 infertility 23 Parkinson's disease 23 bipolar disorder 23 insulinoma 22 bacterial infection 22 myocardial ischemia 22 idiopathic thrombocytopenic purpura 22 cerebral ischemia 22 lung carcinoma 21 colorectal cancer 20 SCH 20 hyperglycemia 20 RGS 20 toxic shock syndrome 19 chronic lymphocytic leukemia 19 oral cancer 19 malaria 19 osteoporosis 19 APC 19 PHA 18 NPC 18 virus infection 18 Adhesion 18 Schistosoma mansoni 18 myocardial infarction 18 HDL3 17 atopic dermatitis 17 worms 17 Evans 17 chronic lymphocytic leukemia 17 gastric cancer 17 male infertility 17 polycystic kidney 16 chronic renal failure 16 acute myeloid leukemia 16 periodontitis 16 epididymis 16 Dissociation 15 congestive heart failure 15 influenza 15 suicide 15 scrapie 15 stomatitis 14 thrombocytopenia 14 thymoma 14 ARF 14 metastases 14 epithelial ovarian cancer 14 anaphylaxis 14 dehydration 14 pulmonary hypertension 14 fits 14 psoriasis 14 inflammatory bowel disease 14 Leukemia 14 disinhibition 13 diphtheria 13 retinoblastoma 13 pulmonary edema 13 myelodysplastic syndrome 13 hypercalcemia 13 listeriosis 13 sarcoma 12 GSH 12 INAD 12 dermatitis 12 bacteremia 12 acute lymphoblastic leukemia 12 drug addiction 12 addiction 12 pruritus 12 NPS 12 bladder cancer 12 Huntington's disease 12 Legionella 12 type 1 diabetes 11 vascular disease 11 MRSA 11 fibrosarcoma 11 chronic pain 11 alcoholism 11 hyperinsulinemia 11 Staphylococcus aureus infection 11 hyperparathyroidism 11 osteoarthritis 11 more...

Symptom pain 134 seizures 35 starvation 33 diarrhea 28 bitter taste 16 analgesia 15 collapse 14 rundown 13 anesthesia 12 respiratory distress 9 ataxia 8 exhaustion 7 hypothermia 6 functional recovery 6 anorexia 5 spasm 5 erythema 5 hypercapnia 4 twitching 4 weakness 4 dry eye 4 acute pain 4 fasciculation 4 acidity 3 tremor 3 hyperoxia 3 cachexia 3 blackout 3 memory loss 2 overweight 2 acute stress 2 insomnia 2 regurgitation 2 spasticity 2 splenomegaly 2 agitation 2 syncope 2 HSA 2 fatigue 2 despair 2 constipation 2 ophthalmoplegia 2 male subfertility 2 thinning 2 dizziness 1 Anoxia 1 sleepiness 1 cerebellar ataxia 1 ENT 1 emaciation 1 muscle cramps 1 hypocapnia 1 paresthesia 1 hypertonia 1 Neuropathic pain 1 myalgia 1 chills 1 hyperacusis 1 vomiting 1 flushing 1 microbial colonization 1 discomfort 1 angina 1 tinnitus 1 muscle rigidity 1 urinary frequency 1 sneezing 1 chest pain 1 nausea 1 paresis 1 apathy 1 clonus 1 impaired motor coordination 1 numbness 1 rhinorrhea 1 hypotonia 1 discomfort 1 Easy bruising 1 rigors 1 abdominal pain 1 Inflammatory pain 1 skin damage 1 cough 1 vertigo 1

Drug caffeine 138 Angiotensin II 98 Histamine 75 IL-2 70 MAP 68 lysine 66 Dermatol 63 Cardiovasc 62 ETA 60 CaCl2 55 CaCl2 55 CaCl2 55 PTH 50 Nephron 46 Ethanol 44 Forskolin 43 ROS 41 Gel 38 Asn 36 ICI 34 Indomethacin 34 IFN-gamma 32 CSF 30 Pronase 26 CTX 21 CDP 20 NADH 19 Glucagon 18 Atropine 17 EE2 17 uPA 17 ABC 16 p75 16 -deoxyadenosine 12 vitamin E 12 lactose 11 Retinoic acid 10 Leaf 10 pyridoxal phosphate 9 K-252a 9 GHRP 9 DNase I 9 Quisqualate 9 Phosphatidylserine 8 Adenosine triphosphate 8 ascorbate 7 Growth hormone 7 CTX 7 CTX 7 Ouabain 7 Fenoldopam 7 Growth hormone 7 Portal 6 Sodium nitroprusside 6 Itraconazole 6 Nephron 6 AraC 6 ENT 6 MRC 6 Iloprost 6 Silica 6 Clonidine 6 Luteinizing 6 Trifluoperazine 5 CoCl2 5 CoCl2 5 NAG 5 NH3 5 Monensin 5 BLM 5 Propofol 5 Secretin 5 CAM 5 CCL 5 PCP 5 Palmitoyl 4 EPA 4 Urokinase 4 Estrogens 4 G-CSF 4 Alanine 4 DEX 4 DHT 4 PDGF B-chain 4 beta-Galactosidase 4 nitroglycerin 4 Streptokinase 4 Doyle 4 CTC 4 TAT 4 Glutathione 4 balanced salt solution 4 DHT 4 GRF 4 Theophylline 3 Kenyan 3 Monit 3 G418 3 Vitamin B 3 Asthma 3 ZnCl2 3 Capsicum 3 Fraction 3 IFN-beta 3 Fentanyl 3 Fructose 3 Pilocarpine 3 Gelatin 3 HCH 3 Amiloride 3 Rolipram 3 DFP 3 Pyridoxal 3 ROC 3 Amiloride 3 ZnCl2 3 Nitric Oxide 3 Brij 96 3 Gramicidin 3 Epigallocatechin 3 Gefitinib 2 Tween 40 2 Cinnarizine 2 Ketoconazole 2 Galactose 2 Fluphenazine 2 Cinacalcet 2 Gabapentin 2 Lisofylline 2 Lipidex 2 Menthol 2 CTC 2 Troglitazone 2 Diphenhydramine 2 Glycerol 2 Nebivolol 2 Sulprostone 2 Adenosine deaminase 2 Agomelatine 2 Omeprazole 2 Xanthium 2 Glide 2 Bifonazole 2 Papain 2 Clofibrate 2 Lovastatin 2 RBT 2 Fluorescein 2 Tenidap 2 Simvastatin 2 IL-11 2 Fluorescein 2 Arsenic trioxide 2 HCG 2 Flurazepam 2 Rutin 2 Dial 2 AC2 2 Ginseng 2 Dihydro 2 more...

Enzyme phospholipase C 18461 protein kinase C 3614 phospholipase A2 1222 protein kinase 1182 mitogen-activated protein kinase 1048 phospholipase D 829 adenylate cyclase 710 thrombin 561 ERK 353 phosphatidylinositol 3-kinase 349 ATPase 336 trypsin 277 alkaline phosphatase 254 lipase 244 focal adhesion kinase 227 MEK 208 phosphodiesterase 178 phosphoinositide 3-kinase 169 lipoprotein lipase 161 PI-PLC 153 calcineurin 150 neuraminidase 150 diacylglycerol kinase 145 lipoxygenase 136 guanylate cyclase 123 NADPH oxidase 107 NADPH oxidase 100 acetylcholinesterase 99 AMPK 98 luciferase 81 CaMKII 79 myosin light chain kinase 74 NO synthase 73 acid phosphatase 73 phosphatidylinositol 4-kinase 73 elastase 64 collagenase 61 caspase-3 60 peroxidase 57 superoxide dismutase 56 glutathione S-transferase 54 5'-nucleotidase 54 urokinase-type plasminogen activator 54 RNase 50 reverse transcriptase 50 lactate dehydrogenase 49 catalase 46 RNase 46 chymotrypsin 45 PARP 43 MAP 40 neuropathy target esterase 40 renin 39 papain 39 apyrase 37 phospholipase A1 37 CPT 36 hyaluronidase 35 PKG 35 DNase 35 ADP-ribosyltransferase 34 monoacylglycerol lipase 32 thromboplastin 32 ADP-ribosyltransferase 31 proteinase K 31 sphingosine kinase 31 transglutaminase 30 PIP kinase 29 GRK5 29 plasmin 28 aequorin 28 hexosaminidase 28 creatine kinase 28 protein phosphatase 2A 27 MDP 27 RNA polymerase 27 AMP-activated protein kinase 27 phosphorylase 26 hyaluronidase 26 GRK2 26 sialidase 25 proteasome 25 neutral sphingomyelinase 24 PTPase 23 ornithine decarboxylase 23 ribonuclease 23 choline kinase 23 adenosine deaminase 23 adenosine deaminase 23 ribonuclease 23 lysozyme 22 CD13 21 IKK 20 tyrosine hydroxylase 20 beta-galactosidase 20 PNGase F 18 sphingomyelin synthase 18 GPI-specific phospholipase C 18 cGMP phosphodiesterase 18 calcium pump 16 CPT 16 beta-glucuronidase 16 PDE 16 CPT 15 ACE 15 cholinesterase 15 xanthine oxidase 15 aminopeptidase P 14 GSK 14 transcriptase 14 phosphatidylinositol phospholipase C 14 NAD glycohydrolase 14 NOS 14 hormone-sensitive lipase 14 carbonic anhydrase 13 chondroitinase 13 chondroitinase 13 CD10 13 gamma-glutamyl transpeptidase 13 p-nitrophenylphosphatase 12 deaminase 12 endoglycosidase H 12 phosphocholine cytidylyltransferase 12 caspase-8 12 Ins(1,4,5)P3 3-kinase 11 cholesterol oxidase 11 ATP synthase 11 triphosphatase 11 deoxyribonuclease 11 heparinase 11 deoxyribonuclease 11 caspase-9 11 diaphorase 10 CPR 10 APC 10 alpha-amylase 10 MMP-3 10 MEKK1 10 beta-lactamase 9 AMPK 9 chitinase 9 ACS 9 lysophosphatidylcholine acyltransferase 9 chloramphenicol acetyltransferase 9 alpha-mannosidase 9 MMP 9 PDK1 9 ceramidase 9 12-lipoxygenase 9 DNA polymerase 9 MIP 8 dipeptidyl peptidase IV 8 phosphoinositide 5-phosphatase 8 tissue plasminogen activator 8 cathepsin G 8 acyl-CoA synthetase 8 leucine aminopeptidase 8 neutrophil elastase 8 pyruvate dehydrogenase 8 tryptase 8 more...

Compound calcium 6064 phosphate 1744 tyrosine 1435 Dec 1364 cAMP 1202 ATP 1094 acetate 1011 GTP 947 sodium 854 DNA 719 ADP 585 AMP 542 ADP 539 ADP 539 glucose 465 glycerol 423 glutamate 401 Clin 383 water 363 oxygen 322 Phosphatidylinositol 317 Phe 309 Triton X-100 291 arginine 285 serine 282 GDP 266 Ins(1,4,5)P3 265 potassium 262 cGMP 257 sulfate 248 nitric oxide 247 COS 232 ethanol 229 leucine 225 UTP 225 Mg2+ 207 SDS 202 5-HT 191 PMA 189 PMA 185 noradrenaline 177 threonine 175 salt 170 alanine 161 zinc 151 EDTA 146 EDTA 146 galactose 141 caffeine 138 prostacyclin 138 methionine 131 Inositol 131 hydrogen 130 cysteine 129 lysine 129 manganese 127 Thrombin 125 1H-pyrrole-2,5-dione 125 tryptophan 122 MEK 122 PGE2 120 Carbachol 118 Angiotensin II 111 Ang II 104 bromide 101 NH2 99 H2O2 96 GABA 93 GABA 91 TPA 89 TPA 89 aldosterone 89 His 89 Bradykinin 88 palmitic acid 86 DAD 85 DAG 85 ammonium 84 ACh 82 Neomycin 82 palmitic acid 82 Arachidonic acid 82 DEAE 81 Cardiol 76 Adenosine 76 PEG 75 Histamine 75 Insulin 72 nickel 72 Phorbol 70 TMB 68 uridine 67 Phosphatidylcholine 67 Asp 67 NMDA 67 phosphorus 66 aluminum 66 nitrous acid 64 iodine 64 ETA 63 UDP 63 TNF 63 PLA 62 PGE 62 Gly 62 Dopamine 61 PEG 60 myristic acid 59 Tyrosine 59 GF 109203X 56 octyl 55 octyl 55 octyl 55 CaCl2 55 myristic acid 54 iron 53 cobalt 52 G11 52 NAD 52 cadmium 51 Cereb 51 inositol 1,4-bisphosphate 51 TRH 50 Guo 50 fMet 50 THP 49 Guo 49 prostaglandin E1 49 THP 49 ACTH 49 Thapsigargin 49 GMP 49 nitrogen 49 tryptophan 48 retinoic acid 48 urea 48 Wortmannin 47 Staurosporine 47 tryptophan 47 proline 47 tryptophan 47 Staurosporine 47 Genistein 44 dicarboxylic acid 44 Vasopressin 44 Ile 43 TSH 43 Forskolin 43 gamma-aminobutyric acid 43 2-methylpiperazine 43 Oxytocin 43 HCl 42 chloroform 42 acetic acid 41 AMPA 41 methanol 40 PAC 40 MAP 40 pyrimidine 40 pyrimidine 40 more...

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