Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.4.3 (phospholipase C)
18,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The actions of trypsin and phospholipase C on th infectivity of Hog Cholera virus (HCV) were studied. Inactivation kinetics reveal a marked decrease of the infectivity of HC virus in the presence of these two agents. The particular sensitivity of this virus towards proteolytic action sheds light on certain of its behavior characteristics in the field. Virus infectivity seems to be dependent on the integrity of membrane phospholipids. No relation was observed between the rate of inactivation and the pathogenicity of the strains.
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PMID:Hog cholera virus : sensitivity to hydrolytic enzymes. 56 Jan 70