Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.4.1 (phosphodiesterase)
 18,767 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
inositoltrisphosphohydrolase 10.7
Hcam3 10.7
HSPDE4D 10.7
PDE8A protein 10.7
CGS-PDE 10.7
membrane interacting protein of RGS16 10.7
triphosphoinositide phosphodiesterase 10.7
ADP-ribosylation factor interacting protein 1 10.7
PDE4B5 10.7
TRBV6-2 10.7
PDE4C-delta109 10.7
alanyl-tRNA synthetase domain containing 1 10.7
PDE4C-426 10.7
PDE4C-delta54 10.7
guanylate cyclase 1, soluble, beta 3 10.7
transmembrane channel-like 7 10.7
phospholipase A2, group VII 10.7
PDE4C-791 10.7
sema domain, transmembrane domain 10.7
TRBV6-3 10.7
DPDE2 10.7
ectonucleotide pyrophosphatase/phosphodiesterase 6 10.7
PRO1598 10.7
PDE7B protein 10.7
nebulin-related anchoring protein isoform C 10.7
PDE1A5 10.7
spectrin, beta, non-erythrocytic 1 10.7
phosphodiesterase 10.7
exonuclease I 10.4
CaM-PDE 10.4
nucleotide pyrophosphatase 10.2
PDE3B protein 10.1
PDE10A1 10.0
cGMP-PDE 10.0
PDE2 10.0
PDE1C 9.9
Cyclic nucleotide phosphodiesterase 9.9
NPP2 9.9
PDE4A 9.9
PDE8A 9.9
more...
Disease
Hyperdynamic septic shock 10.7
Primary apnoea 10.7
SCAN1 9.9
organic sexual dysfunction 9.7
PDE 9.2
LCA4 8.7
Gastric mucosal lesion 8.7
Mietens' syndrome 8.7
Drug-induced sexual dysfunction 8.7
Nonarteritic anterior ischemic optic neuropathy (NAION) 8.0
erectile dysfunction 7.9
acrodysostosis 7.9
GACI 7.9
Toxic optic neuropathy 7.9
RP26 7.6
Neuroleptic-induced tardive dyskinesia 7.6
Portopulmonary hypertension 7.5
female sexual arousal disorder 7.4
Pulmonary arterial hypertension 7.3
Radiation esophagitis 7.1
learning defect 7.1
Chromium deficiency 6.9
High altitude pulmonary edema 6.9
Decompensated heart failure 6.8
Free plasma hemoglobin 6.7
IHG 6.7
premature ejaculation 6.7
PPD2 6.6
Ejaculatory dysfunction 6.6
Proximal renal tubular acidosis 6.6
Idiopathic pulmonary arterial hypertension 6.5
Retinal dystrophy 6.5
Persistent pulmonary hypertension 6.3
Female sexual dysfunction 6.3
Axonal Neuropathy 6.3
CHEST 6.3
persistent pulmonary hypertension of the newborn 6.3
sexual dysfunction and infertility 6.2
Performance anxiety 6.2
Pleuropneumonia 6.2
more...
Symptom
Ureteric colic 8.7
Central cyanosis 7.7
Muscle fibrosis 7.4
Lower urinary tract symptoms 7.1
Hangover 5.1
nasal congestion 4.9
astasia 4.8
Urinary symptoms 4.5
skin pain 4.5
Periodic breathing 4.3
Visual symptoms 3.9
flushing 3.8
photopsia 3.7
nocturnal polyuria 3.5
No adverse effect 3.4
bitter taste 3.3
Decreased activity 3.3
Spastic 3.3
pachyonychia 3.2
retching 3.2
Noise-induced hearing loss 3.1
tonic seizure 3.0
inanition 2.9
motor symptom 2.8
hyperoxia 2.8
rundown 2.8
twitching 2.7
memory loss 2.7
despair 2.7
prostatism 2.6
elbow pain 2.5
autodigestion 2.4
Excitability 2.4
nausea 2.3
starvation 2.3
polyuria 2.3
hyperacusis 2.2
hangover 2.2
clonus 2.2
spasm 2.2
more...
Drug
Quazinone 10.7
Piclamilast 10.4
Piclamilast 10.4
Indolidan 10.2
Rolipram 10.2
Cilomilast 10.1
Avanafil 10.1
Roflumilast 10.0
Roflumilast 10.0
Vardenafil 9.8
Levitra 9.8
Enoximone 9.8
R-Rolipram 9.7
2-Fluoroadenosine 9.7
Ibudilast 9.6
Piroximone 9.5
Levitra 9.5
Cilostazol 9.4
Pimobendan 9.4
Quazodine 9.1
Inocor 9.1
Ethyl icosapentate 9.1
Carbazeran 9.1
Primacor 9.1
Warfarin potassium 9.1
Bemoradan 8.9
Viagra 8.9
Toborinone 8.9
Amrinone 8.8
Viagra 8.7
Talniflumate 8.7
Monoammonium glycyrrhizinate 8.7
Etacrynic acid 8.7
Primacor 8.4
S-Ethylisothiourea 8.4
Anginin 8.4
CIA 8.4
Vesnarinone 8.4
Vinpocetine 8.3
Lysophosphatidylglycerol 8.1
more...
Enzyme
mannosylphosphodolichol phosphodiesterase 10.7
phosphodiesterase 10.7
exonuclease I 10.6
yeast ribonuclease 10.1
AcpH 10.1
glycerophosphocholine cholinephosphodiesterase 10.0
nucleotide pyrophosphatase 9.8
exoribonuclease H 9.7
cGMP phosphodiesterase 9.5
PDE 9.4
CMP-sialic acid hydrolase 9.4
glycerophosphocholine phosphodiesterase 9.3
cytochrome c methyltransferase 9.1
aminopeptidase S 9.1
dTMPase 9.1
EC 2.7.7.53 8.9
EC 4.1.1.46 8.7
EC 3.6.1.29 8.6
cytidylate cyclase 8.6
lysophospholipase D 8.5
ribonuclease F 8.4
EC 3.6.1.17 8.3
exonuclease VII 8.3
3'-exonuclease 8.2
3'-phosphatase 8.2
ADP-sugar pyrophosphatase 8.1
DNA 3'-phosphatase 7.9
UDP-glucose:glycoprotein glucose-1-phosphotransferase 7.9
pterin deaminase 7.9
FAD-AMP lyase 7.9
phosphoglycerol transferase 7.9
7alpha-dehydroxylase 7.6
lysoplasmalogenase 7.6
UDP-sugar hydrolase 7.6
oligoribonuclease 7.5
ADP-ribosylarginine hydrolase 7.5
phosphoinositide 5-phosphatase 7.4
deoxynucleoside monophosphate kinase 7.4
venom phosphodiesterase 7.3
adenylate cyclase 7.3
more...
Compound
1-ethyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione 10.7
N-neopentylacetamide 10.7
C19H16O3 10.7
C22H30N6 10.7
C19H16O3 10.7
C19H16O3 10.7
Linderane 10.7
Leniquinsin 10.7
C19H16O3 10.7
8-Bromoinosine 10.7
C19H16O3 10.7
C19H16O3 10.7
Olprinone hydrochloride 10.7
N-(3,4-dimethoxyphenyl)acetamide 10.7
Cytosine arabinoside monophosphate 10.7
SQ 20009 10.0
2-Fluoroadenosine 9.7
Dehydroheliotridine 9.7
Atherosperminine 9.7
AMP 2'-phosphate 9.7
C16H16O3 9.7
Milrinone lactate 9.7
Sildenafil 9.5
Milrinone 9.4
Reticulol 9.1
Hydrocortisone phosphate 9.1
C13H10O3 9.1
Sch 15280 9.1
Tiaramide hydrochloride 9.1
C14H20O3 9.1
C20H24N2O2 9.1
Phthalazinol 9.1
2-Phenylaminoadenosine 9.1
2-imidazolidinone 8.9
Sulmazole 8.9
Baxacor 8.7
C19H16O2 8.7
C6H13NO3 8.7
Etacrynic acid 8.7
Pentoxyl 8.7
more...