Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.4.1 (phosphodiesterase)
 18,767 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
phosphodiesterase 17939
AMP 2695
adenylate cyclase 1652
Sep 1300
Mol 1073
calmodulin 1041
PDE 865
ATP 730
nucleotide pyrophosphatase 684
PDE4 646
insulin 615
adenylyl cyclase 581
cyclic nucleotide phosphodiesterase 567
guanylate cyclase 565
GTP 403
GMP 398
cyclic AMP phosphodiesterase 382
PDE5 374
nitric oxide synthase 354
ADP 340
cAMP-dependent protein kinase 336
cytokine 291
PKA 280
endothelin receptor 268
rhodopsin 267
cGMP phosphodiesterase 257
ATPase 255
alkaline phosphatase 254
Phosphodiesterase 250
tumor necrosis factor 249
glucagon 240
collagen 237
phosphatase 235
PKG 231
lipopolysaccharide 219
guanylyl cyclase 211
exonuclease I 211
membrane-bound 204
5'-nucleotidase 189
polypeptide 188
PDE2 182
soluble guanylyl cyclase 178
Dictyostelium 170
adenosine receptor 160
Gen 159
TNF 154
endonuclease 149
thrombin 149
vasopressin 145
calcium channel 144
cyclooxygenase 142
PDE4B 132
pyrophosphatase 124
SDS 124
adenyl cyclase 122
Pseudomonas 112
olfactory 110
NMR 109
GDP 109
TNF-alpha 108
adenosine deaminase 106
PDE4A 104
natriuretic peptide 98
DNA polymerase 97
dimeric 97
microsomal 94
CGI 94
renin 94
myelin basic protein 93
Autotaxin 91
beta-endorphin 90
atrial natriuretic peptide 90
angiotensin II 90
endoplasmic reticulum 89
axonal 88
inducible nitric oxide synthase 88
IL-6 88
spermatozoa 86
tyrosine kinase 86
FSH 86
calcineurin 85
CA1 85
vasoactive intestinal peptide 83
cGMP-PDE 82
LPS 82
IgE 82
phosphomonoesterase 81
interferon 81
glycoprotein 80
GTPase 80
CREB 79
5-hydroxytryptamine 78
beta 1 78
IL-4 78
endothelin-1 78
acid phosphatase 77
superoxide dismutase 75
caspase-3 73
parathyroid hormone 73
somatostatin 73
cAMP-specific phosphodiesterase 70
muscarinic receptor 70
bradykinin 69
IL-10 68
PDE3B 67
NAD 67
acetylcholinesterase 67
calcitonin 66
epididymal 64
endothelial nitric oxide synthase 64
protein phosphatase 64
Rho 64
glial fibrillary acidic protein 62
hemoglobin 62
cardiac muscle 61
eNOS 61
phospholipase A2 60
myosin 60
ACTH 60
MAPK 59
histone 59
secretin 58
prolactin 57
arrestin 57
GTP-binding protein 57
PKC 57
neuronal nitric oxide synthase 56
ERK 56
Cyclic nucleotide phosphodiesterase 55
IL-5 55
COPD 55
myeloperoxidase 53
tyrosine hydroxylase 53
brain-derived neurotrophic factor 52
GABA 52
topoisomerase I 52
threonine 52
membrane protein 51
substance P 51
GAF 51
p38 50
vascular endothelial growth factor 50
atrial natriuretic factor 50
Aplysia 50
serum albumin 49
PDE10A 49
vasoactive intestinal peptide (VIP) 48
PDE7 48
interferon-gamma 48
lactate dehydrogenase 47
NPP1 47
collagenase 47
IL-8 47
albumin 47
myosin light chain kinase 47
dunce 47
phospholipase D 46
fused 46
tRNA 46
esterase 46
deoxyribonuclease 45
catalase 45
thymus 45
ERK1 45
insulin receptor 45
MIX 45
tumor necrosis factor alpha 44
C-type natriuretic peptide 44
reductase 44
CPT 44
NMDA receptor 43
protein kinase inhibitor 43
IFN-gamma 43
collecting duct 43
PDE2A 43
ubiquitin 43
phospholipase 43
Pol 43
prostaglandin I2 43
epidermal growth factor 42
mast cell 41
RNase 41
nerve growth factor 40
calmodulin-dependent phosphodiesterase 40
Janus kinase 40
ENPP1 40
gut 40
interleukin-6 40
lectin 39
PC-1 39
vascular endothelium 39
follicle-stimulating hormone 39
PDE1A 39
fibrinogen 39
PLA 38
TDP1 38
extracellular signal-regulated kinase 38
PTH 38
troponin C 37
IFN 37
A-I 37
histone deacetylase 37
PKI 37
cytochrome P450 37
SIN 37
rd1 37
EMD 37
Met 36
leptin 36
arginine vasopressin 36
RhoA 36
Ang II 36
NADH 35
SOD 35
adenosine A1 receptor 35
IL-13 35
PDE5A 35
IL-2 35
phospholamban 34
thyroid hormone 34
CNPase 34
cystic fibrosis transmembrane conductance regulator 34
Rod 34
beta-glucuronidase 33
AKT 33
PI3K 33
IL-1 33
alkaline phosphomonoesterase 33
lipase 33
cholecystokinin 33
phosphatidylinositol 3-kinase 33
proteolipid protein 33
PDE1C 33
Bcl-2 33
hyaluronidase 33
growth hormone 32
ornithine decarboxylase 32
ecto-5'-nucleotidase 32
GSH 32
ACS 32
oxytocin 32
fibronectin 32
G protein-coupled receptor 31
hormone-sensitive lipase 31
CD4 31
chorionic gonadotropin 31
SNAP 31
platelet-derived growth factor 31
peroxidase 31
B10 30
lipoxygenase 30
chemokine 30
lymphoid 30
NAD+ 30
protein kinase B 30
Cyclic AMP phosphodiesterase 29
COX-2 29
NADPH 29
IL-1 beta 29
Men 29
p38 mitogen-activated protein kinase 29
ACE 29
ROS 29
rhodopsin kinase 29
CA3 29
glycogen phosphorylase 28
glucocorticoid receptor 28
interleukin-10 28
PDE4C 28
TOF 28
IL-17 28
MEK 28
CAS 28
CD73 27
PAF 27
CO2 27
GSK 27
PDE11A 27
guanine nucleotide regulatory protein 27
alpha, beta 27
adenosine triphosphatase 27
vasodilator-stimulated phosphoprotein 27
pituitary adenylate cyclase-activating polypeptide 27
NPP2 26
p53 26
G-protein-coupled receptor 26
Rho kinase 26
DNase 26
PDE1B 26
phosphatidylinositol-specific 26
aromatase 26
proliferating cell nuclear antigen 25
PDE7A 25
DNA ligase 25
interleukin-4 25
5-lipoxygenase 25
phosphoprotein 25
MAP kinase 25
cAMP response element-binding protein 25
myelin-associated glycoprotein 25
tyrosyl-DNA phosphodiesterase 1 25
opioid receptor 25
mTOR 25
proteasome 25
DNA polymerase alpha 25
endothelin A receptor 24
myosin light chain 24
glutamate receptor 24
erythropoietin 24
PDE8A 24
DOS 24
mitogen-activated protein 24
troponin I 24
matrix metalloproteinase 24
inhibitor 2 24
CYP3A4 24
RNase L 24
Guanylate cyclase 23
amyloid precursor protein 23
THP 23
more...
Disease
erectile dysfunction 1006
PDE 865
hypertension 596
heart failure 509
cancer 498
pulmonary hypertension 473
asthma 438
tumor 365
diabetes 358
chronic obstructive pulmonary disease 339
cholera 290
pertussis 234
stroke 233
depression 233
ischemia 232
congestive heart failure 190
NAME 150
atherosclerosis 133
atopic dermatitis 132
Pulmonary arterial hypertension 128
Alzheimer's disease 127
cardiovascular disease 127
obesity 125
SDS 124
psoriasis 113
myocardial infarction 109
heart disease 102
sexual dysfunction 95
neuroblastoma 91
right heart failure 87
myocardial ischemia 82
type 2 diabetes 75
schizophrenia 75
glioma 73
cold 72
coronary artery disease 72
multiple sclerosis 72
retinitis pigmentosa 71
prostate cancer 70
melanoma 70
HIV 70
cognitive impairment 69
vascular disease 66
hepatocellular carcinoma 65
sepsis 63
sepsis 60
PSS 59
carcinoma 58
COPD 55
intermittent claudication 54
plaque 53
Parkinson's disease 53
breast cancer 52
psoriatic arthritis 51
pulmonary edema 49
hypogonadism 48
Mycobacterium 48
lymphoma 48
uterus 48
cerebral ischemia 47
cardiomyopathy 46
cystic fibrosis 46
premature ejaculation 45
lung disease 44
tuberculosis 44
leukemia 44
pruritus 43
tumor growth 43
neuropathy 43
dyspepsia 41
SEM 40
cirrhosis 40
metabolic syndrome 40
arthritis 39
EMD 39
encephalomyelitis 39
dementia 38
sympathomimetic 38
ventricular hypertrophy 37
primary pulmonary hypertension 37
impotence 36
lung cancer 35
dilated cardiomyopathy 35
rheumatoid arthritis 35
tumorigenesis 35
priapism 33
GSH 32
carcinogenesis 32
hyperglycemia 32
skin disease 32
Raynaud's phenomenon 31
blindness 31
liver disease 29
renal disease 29
renal failure 28
pheochromocytoma 28
acute myocardial infarction 28
connective tissue disease 28
persistent pulmonary hypertension of the newborn 28
coronary heart disease 28
memory impairment 28
major depressive disorder 28
PAF 27
peripheral vascular disease 26
chronic bronchitis 25
dermatitis 25
Brown 25
Huntington's disease 25
portal hypertension 25
colon cancer 24
respiratory disease 24
osteoporosis 24
tumor progression 23
infectious diseases 23
scleroderma 23
Evans 23
immunodeficiency 23
hypercholesterolemia 23
adenocarcinoma 23
eosinophilia 23
subarachnoid hemorrhage 23
colorectal cancer 22
AIDS 22
virus infection 22
pneumonia 22
Peyronie's disease 22
MCF 22
bronchopulmonary dysplasia 22
bronchospasm 22
astrocytoma 22
mole 21
mole 21
hyperlipidemia 21
inflammatory bowel disease 21
epididymis 21
SCH 21
autoimmune disease 21
tetanus 21
metastases 21
insulinoma 20
mental illness 20
preeclampsia 20
ATM 20
emphysema 19
infertility 19
respiratory failure 19
sickle cell disease 19
Blocking 19
SCAN1 19
worms 19
epilepsy 19
incontinence 19
cerebral infarction 19
Endothelial dysfunction 18
chronic disease 18
hypothyroidism 18
thrombocytopenia 18
bipolar disorder 18
LCA 18
idiopathic pulmonary fibrosis 18
fits 18
malaria 17
ventricular fibrillation 17
proteinuria 17
SAR 17
urethra 17
influenza 17
Duchenne muscular dystrophy 16
colitis 16
idiopathic dilated cardiomyopathy 16
intraocular pressure 16
chronic lymphocytic leukemia 16
African trypanosomiasis 16
anaphylaxis 16
Legionella 16
chronic lymphocytic leukemia 16
herpes simplex 16
allergic rhinitis 16
hepatitis 16
hepatic encephalopathy 16
pulmonary fibrosis 16
multiple myeloma 15
Raynaud 15
diabetic nephropathy 15
Sexual dysfunction 15
ureter 15
migraine 15
left ventricular failure 15
dyslipidemia 14
fatty liver 14
hypoglycemia 14
NPH 14
B-cell lymphoma 14
dysplasia 14
chronic renal failure 14
Best 14
glioblastoma 14
Schistosoma mansoni 14
psychosis 14
Klebsiella 13
hyperthyroidism 13
hyperinsulinemia 13
nephrogenic diabetes insipidus 13
peripheral neuropathy 13
osteosarcoma 13
interstitial lung disease 13
adult respiratory distress syndrome 13
claudication 13
retinoblastoma 13
incontinence 12
Niemann-Pick 12
Chagas 12
rare disease 12
vasculitis 12
systemic lupus erythematosus 12
Yersinia 12
glaucoma 12
hepatitis B 12
Bordetella 12
pulmonary embolism 11
Pituitary 11
pituitary tumor 11
acute promyelocytic leukemia 11
aqueous humor 11
nephrotic syndrome 11
coronary occlusion 11
arteriopathy 11
gastroesophageal reflux disease 11
schistosomiasis 11
cerebral vasospasm 11
essential hypertension 11
myocarditis 11
retinopathy 11
Infection 10
muscular dystrophy 10
diabetic neuropathy 10
West 10
Haemophilus 10
Portopulmonary hypertension 10
DBA 10
Hymenolepis 10
skin cancer 10
malnutrition 10
calcinosis 10
dehydration 10
Still 10
polycystic kidney 10
acute renal failure 10
hernia 10
eczema 10
cor pulmonale 9
chondrocalcinosis 9
myopathy 9
neurological disease 9
achromatopsia 9
non-small cell lung cancer 9
arthrodesis 9
anemia 9
acrodysostosis 9
ischemic cardiomyopathy 9
Steroids 9
sarcoidosis 9
brain tumor 9
glomerulonephritis 9
rhinitis 9
enthesitis 9
Down syndrome 8
dactylitis 8
ulcerative colitis 8
sarcoma 8
ICS 8
hypoactive sexual desire disorder 8
erythroleukemia 8
acute myeloid leukemia 8
unstable angina 8
veno-occlusive disease 8
Epstein 8
macular degeneration 8
amyotrophic lateral sclerosis 8
lung carcinoma 8
idiopathic thrombocytopenic purpura 8
liver fibrosis 8
vagina 8
uveitis 8
APC 8
PDB 8
mastocytoma 8
LTD 8
Crohn's disease 8
rickets 8
bacterial infection 8
glioblastoma multiforme 7
ADH 7
stomatitis 7
obstructive sleep apnea 7
muscular atrophy 7
neutropenia 7
glomerulosclerosis 7
acute lymphoblastic leukemia 7
chronic pain 7
lymphoblastic leukemia 7
renal cell carcinoma 7
leishmaniasis 7
endotoxic shock 7
mitral stenosis 7
STD 7
lupus 7
amnesia 7
parkinsonism 7
Hodgkin's disease 7
ischemic optic neuropathy 7
glucose intolerance 7
ICP 7
alcoholism 7
bronchiectasis 7
sinus tachycardia 7
cholestasis 7
brain edema 7
MRS 7
mental retardation 7
more...
Symptom
headache 130
pain 121
vomiting 76
starvation 74
anesthesia 72
nausea 70
diarrhea 68
dyspnea 52
flushing 51
seizures 48
fatigue 39
ataxia 29
angina 28
hypothermia 27
functional recovery 23
cough 22
hyperoxia 22
respiratory distress 21
spasm 20
nasal congestion 20
dizziness 19
analgesia 17
nausea and vomiting 17
Lower urinary tract symptoms 15
tremor 15
memory loss 14
syncope 13
collapse 13
thinning 10
hypercapnia 10
acute pain 9
chest pain 9
constipation 9
polyuria 9
weakness 9
myalgia 9
erythema 9
abdominal pain 8
agitation 8
cyanosis 8
bitter taste 8
twitching 8
overweight 8
exertional dyspnea 7
exhaustion 7
discomfort 7
insomnia 7
back pain 7
discomfort 7
despair 6
cachexia 6
colic 6
polydipsia 5
anorexia 5
pelvic pain 4
chronic cough 4
vertigo 4
incoordination 4
abdominal discomfort 3
tachypnea 3
photophobia 3
Decreased activity 3
pallor 3
ophthalmoplegia 3
arthralgia 3
dysuria 3
HSA 3
retching 3
splenomegaly 2
chorea 2
No adverse effect 2
clonus 2
shortness of breath 2
motor symptom 2
tinnitus 2
productive cough 2
acute stress 2
acidity 2
bradykinesia 2
rundown 2
blurred vision 2
astasia 2
hemoptysis 2
catatonia 2
spasticity 2
Neuropathic pain 2
autodigestion 1
urinary frequency 1
lethargy 1
POA 1
hangover 1
swollen joints 1
Spastic 1
Urinary symptoms 1
inanition 1
cerebellar ataxia 1
Welt 1
photopsia 1
numbness 1
loss of taste 1
physical appearance 1
neurological disability 1
oliguria 1
Ureteric colic 1
Excitability 1
muscle rigidity 1
rhinorrhea 1
Anoxia 1
sleepiness 1
dysarthria 1
dystonia 1
nocturnal polyuria 1
presyncope 1
Ill 1
Visual symptoms 1
enuresis 1
Involuntary Movement 1
prostatism 1
skin pain 1
Hangover 1
dry eye 1
tonic seizure 1
Wind 1
Muscle fibrosis 1
hyperacusis 1
pachyonychia 1
Noise-induced hearing loss 1
Central cyanosis 1
skin irritation 1
renal colic 1
hepatosplenomegaly 1
hypotonia 1
elbow pain 1
asynergy 1
Periodic breathing 1
wheezing 1
leg edema 1
Drug
caffeine 375
Rolipram 301
Cardiovasc 296
Forskolin 240
Theophylline 182
Cilostazol 168
Viagra 166
CIA 156
Dermatol 152
Viagra 118
Vardenafil 94
Roflumilast 78
Roflumilast 78
Enoximone 68
ICI 68
Papaverine 68
Amrinone 63
nitroglycerin 62
Histamine 55
lysine 54
Nephron 53
CaCl2 49
CaCl2 49
CaCl2 49
Gel 48
Indomethacin 46
Levosimendan 46
Glucagon 43
MAP 41
IFN-gamma 41
PTH 38
NADH 37
IL-2 35
Sodium nitroprusside 35
Levitra 31
Levitra 31
Asthma 31
ROS 29
Pimobendan 29
Cilomilast 28
Vinpocetine 27
Ibudilast 26
Salbutamol 23
Bosentan 22
Bosentan 22
Nitric Oxide 21
Atropine 20
CSF 20
CTX 19
Trifluoperazine 19
Asn 18
FAD 18
Methylene blue 17
Iloprost 17
Ouabain 17
DNase I 17
Secretin 16
Ethanol 16
Fraction 16
-deoxyadenosine 15
Adenosine deaminase 15
Vesnarinone 15
Phentolamine 14
ascorbate 14
CDP 14
Ringer's solution 14
Bayer 13
Angiotensin II 13
Trapidil 13
EE2 12
Avanafil 12
Apomorphine 12
lactose 11
Clonidine 11
Heme 10
ABC 10
Propentofylline 10
ETS 9
Anagrelide 9
Piclamilast 9
Piclamilast 9
vitamin E 9
Digitalis 8
balanced salt solution 7
ETA 7
Treprostinil 7
Luteinizing 7
Enprofylline 7
Retinoic acid 7
MgSO4 7
Piroximone 7
p75 7
Nesiritide 7
Trental 7
CoCl2 7
CoCl2 7
GRF 6
Xanthium 6
Dihydro 6
Pronase 6
CTX 6
Alanine 6
Amiloride 6
CTX 6
niacin 5
Glycerol 5
EPI 5
Glycyrrhiza 5
MRC 5
VCR 5
Amiloride 5
Beraprost 5
Portal 5
Fragment 5
Indolidan 5
Adenosine triphosphate 5
Leaf 5
PCP 5
Albumin 5
NH3 5
Prednisolone 5
Nephron 4
Dial 4
Cibacron Blue 4
Meconium 4
Fluphenazine 4
Docetaxel 4
Imatinib 4
BLM 4
Donepezil 4
ADM 4
citric acid 4
BH4 4
AC2 4
CPZ 4
Cicletanine 4
Biopolymers 4
Quazinone 4
Ranitidine 4
Scopolamine 3
Growth hormone 3
Vitamin E 3
Taxol 3
ROC 3
ampicillin 3
Etoposide 3
Nimesulide 3
G-CSF 3
L-tyrosine 3
NVP 3
Toborinone 3
Allergen 3
Ephedrae Herba 3
Carbenoxolone 3
Ketotifen 3
Triclosan 3
ACT 3
Monensin 3
HPMPC 3
Doxofylline 3
ADR 3
APD 3
FeCl3 3
Camp 3
Fluorescein 3
HCG 3
CAM 3
Growth hormone 3
Flosequinan 3
Azithromycin 3
Lovastatin 3
Cimetidine 3
Cimetidine 3
Fructose 3
TAT 3
IFN-beta 3
Methylprednisolone 3
GEO 2
Cisapride 2
beta-Galactosidase 2
Pravastatin 2
Felodipine 2
AZT 2
CET 2
Atenolol 2
Lisuride 2
Ginseng 2
EPA 2
DEX 2
7-Nitroindazole 2
DDAVP 2
Infliximab 2
CTZ 2
Aloe 2
Parkin 2
Stelazine 2
RAL 2
Kenyan 2
Rituximab 2
TES 2
Dopexamine 2
DHT 2
Budesonide 2
Deoxyadenosine 2
TAK 2
Bumetanide 2
AHF 2
Adriamycin 2
Fenoterol 2
Tranilast 2
THF 2
Alfuzosin 2
Lactose 2
Epinastine 2
Silodosin 2
Phosphatidylserine 2
DDAVP 2
Photofrin 2
Omnic 2
BCG vaccine 2
Monit 2
Gabexate mesilate 2
G418 2
2'-Deoxyadenosine 2
pyridoxal phosphate 2
Myricetin 2
Parkin 2
Oxaliplatin 2
Bemoradan 2
AZT 2
NAG 2
Ginger 2
Tacrolimus 2
Infliximab 2
9-THC 2
Sorafenib 2
PMEA 2
Gelatin 2
Mutagen 2
Muse 2
Acitretin 2
linolenate 2
FLP 2
Amlexanox 2
Fluorescein 2
DHT 2
MIL 2
Diamminedichloroplatinum 1
Moclobemide 1
R-Rolipram 1
Orlistat 1
Inocor 1
CPR 1
Primacor 1
Dextrose 1
Jujube 1
Argatroban 1
Tamsulosin hydrochloride 1
Bevacizumab 1
Sodium alginate 1
Nipent 1
Valproic Acid 1
Prenylamine 1
Flavin 1
Vitamin B 1
Finasteride 1
Dithranol 1
Wine 1
Bisacodyl 1
Agrylin 1
GNA 1
Capsicum 1
Cidofovir 1
Gleevec 1
Terlipressin 1
Cyclandelate 1
Carbazeran 1
2-Methoxyestradiol 1
Atipamezole 1
Pinellia tuber 1
PFA 1
Serum albumin 1
Visken 1
Dutasteride 1
Glutamic acid 1
FSH-beta 1
RFP 1
Escitalopram 1
S-Ethylisothiourea 1
Rocuronium 1
Pitressin 1
TTC 1
Campath 1
Tolfenamic acid 1
Acyclovir 1
Histalog 1
NBT 1
Senna 1
Hydrochlorothiazide 1
Premarin 1
Methyldopa 1
Quazodine 1
Lead acetate 1
Atosiban 1
Leminoprazole 1
PPA 1
Monoammonium glycyrrhizinate 1
Ridogrel 1
Stenorol 1
Zmax 1
Scutellaria root 1
Orion 1
Frontal 1
Singular 1
Glide 1
Etravirine 1
Hypaque 1
PT-141 1
Tubocurarine 1
FSH-beta 1
more...
Enzyme
phosphodiesterase 18767
adenylate cyclase 1785
protein kinase 1759
PDE 1513
guanylate cyclase 774
cGMP phosphodiesterase 409
protein kinase C 384
alkaline phosphatase 359
AMPK 348
ATPase 302
PKG 231
mitogen-activated protein kinase 223
exonuclease I 211
NO synthase 203
5'-nucleotidase 196
nucleotide pyrophosphatase 193
phospholipase C 178
acid phosphatase 163
DNA polymerase 159
calcineurin 155
thrombin 150
endonuclease 149
trypsin 132
phospholipase A2 114
adenosine deaminase 109
adenosine deaminase 106
RNase 96
renin 94
peroxidase 94
RNase 92
superoxide dismutase 87
ERK 85
acetylcholinesterase 73
3'-exonuclease 71
topoisomerase 71
DNase 68
topoisomerase 66
myosin light chain kinase 65
NOS 64
luciferase 63
phosphorylase 61
caspase-3 58
lactate dehydrogenase 55
collagenase 54
ACE 53
DNA ligase 50
tyrosine hydroxylase 50
DNA ligase 50
focal adhesion kinase 48
catalase 48
lysophospholipase D 47
ribonuclease 46
phospholipase D 46
ribonuclease 46
beta-galactosidase 46
reverse transcriptase 46
CPT 45
CPT 44
CPT 44
venom phosphodiesterase 43
nucleotidase 42
lipase 40
PARP 38
MEK 38
CaMKII 37
NADPH oxidase 37
hyaluronidase 36
NADPH oxidase 35
polynucleotide kinase 35
rhodopsin kinase 33
elastase 33
hyaluronidase 33
phosphatidylinositol 3-kinase 33
ornithine decarboxylase 32
ACS 32
hormone-sensitive lipase 31
beta-glucuronidase 31
3'-phosphatase 30
lipoxygenase 30
CD10 29
arginase 29
monoamine oxidase 29
RNA polymerase 28
GSK 27
AMP-activated protein kinase 27
proteasome 26
apyrase 26
RNA ligase 26
chymotrypsin 25
MAP 24
CYP3A4 24
sulfatase 24
PAH 23
phosphoinositide 3-kinase 23
Mg2+-ATPase 23
aequorin 23
deaminase 22
CNPase 22
adenylate kinase 22
deoxyribonuclease 22
xanthine oxidase 22
glutathione S-transferase 21
histidine kinase 20
deoxyribonuclease 20
glutamine synthetase 20
neuropathy target esterase 20
gamma-glutamyl transpeptidase 19
N-acetyltransferase 19
carbonic anhydrase 18
tissue plasminogen activator 18
alanine aminotransferase 18
phosphoenolpyruvate carboxykinase 18
diacylglycerol kinase 18
phosphoenolpyruvate carboxykinase 17
phosphoenolpyruvate carboxykinase 17
thymidine kinase 17
P-glycoprotein 17
pyruvate kinase 17
cholinesterase 17
beta-lactamase 17
micrococcal nuclease 17
NADPH-diaphorase 16
arylalkylamine N-acetyltransferase 16
tyrosinase 16
creatine kinase 16
alpha-mannosidase 16
lipoprotein lipase 16
ADPase 16
alcohol dehydrogenase 16
protein phosphatase 2A 16
diaphorase 15
glucose-6-phosphatase 15
leucine aminopeptidase 15
p-nitrophenylphosphatase 15
prostaglandin synthetase 14
DNase II 14
alpha-glucosidase 14
glutathione peroxidase 14
phosphorylase kinase 14
triphosphatase 14
NAD glycohydrolase 14
glucose-6-phosphate dehydrogenase 14
exonuclease VII 13
paraoxonase 13
ADP-ribosyltransferase 13
CPR 13
transcriptase 13
aldehyde dehydrogenase 13
cdc2 13
ADP-ribosyltransferase 13
neutrophil elastase 12
succinate dehydrogenase 12
aspartate aminotransferase 12
adenosine kinase 12
thromboplastin 12
PI-PLC 11
chloramphenicol acetyltransferase 11
hexosaminidase 11
RNase H 11
kallikrein 10
arylsulfatase 10
NQO1 10
AMPK 10
choline acetyltransferase 10
glycerophosphocholine phosphodiesterase 9
5alpha-reductase 9
beta-glucosidase 9
exoribonuclease 9
carboxylesterase 9
calcium pump 9
beta-glucosidase 9
lysozyme 9
5alpha-reductase 9
hexokinase 9
glycerophosphocholine cholinephosphodiesterase 8
tyrosine aminotransferase 8
choline kinase 8
urokinase-type plasminogen activator 8
poly(ADP-ribose) glycohydrolase 8
phosphofructokinase 8
ATP diphosphohydrolase 8
Escherichia coli exonuclease III 8
tryptase 8
IMP dehydrogenase 8
S1 nuclease 8
urease 7
neutral sphingomyelinase 7
GMP synthetase 7
IKK 7
histidine decarboxylase 7
cathepsin D 7
phosphatidylinositol 4-kinase 7
tryptophan 2,3-dioxygenase 7
lambda exonuclease 7
purine nucleoside phosphorylase 7
exonuclease V 7
prostate-specific antigen 7
pyruvate dehydrogenase 7
urease 7
CD13 7
ADH 7
SPT 7
aldose reductase 7
cellulose synthase 7
diaphorase 6
SPT 6
glycerophosphodiester phosphodiesterase 6
heme oxygenase 6
AMP deaminase 6
alpha-L-fucosidase 6
GRK5 6
alpha-amylase 6
caspase-8 6
caspase-9 6
thermolysin 6
PCP 6
APC 6
phospholipase A1 6
polynucleotide phosphorylase 6
aldolase 6
dihydrofolate reductase 6
glucose oxidase 6
dipeptidyl peptidase IV 6
pepsin 6
phytase 6
phosphoinositide 5-phosphatase 6
PTPase 6
cellulose synthase 6
thromboxane synthase 6
EC 3.6.1.17 6
phytase 6
neuraminidase 6
papain 6
nucleoside hydrolase 5
AcpH 5
glycerol-3-phosphate dehydrogenase 5
PIP kinase 5
phenylethanolamine N-methyltransferase 5
pyruvate dehydrogenase 5
fumarase 5
myosin ATPase 5
glycerol-3-phosphate dehydrogenase 5
glyceraldehyde-3-phosphate dehydrogenase 5
cellulase 5
pyruvate dehydrogenase 5
transglutaminase 5
invertase 5
tRNase Z 5
plasmin 5
proteinase K 5
aldehyde dehydrogenase 5
AP lyase 5
BAL 5
glyceraldehyde-3-phosphate dehydrogenase 5
diamine oxidase 5
cytochrome oxidase 5
MIP 5
PDK1 5
caspase-1 5
glucokinase 5
PGM 4
DOPA decarboxylase 4
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
GRK2 4
GTP cyclohydrolase I 4
isoamylase 4
isocitrate dehydrogenase 4
chondroitinase 4
malate dehydrogenase 4
oligoribonuclease 4
pullulanase 4
Thy1 4
proton-translocating ATPase 4
SPC 4
firefly luciferase 4
demethylase 4
MDP 4
citrate synthase 4
aldehyde dehydrogenase 4
ATP synthase 4
fructose 1,6-bisphosphatase 4
type 1 protein phosphatase 4
subtilisin 4
DNA 3'-phosphatase 4
soluble epoxide hydrolase 4
MDR 4
EC 3.6.1.29 4
sialyltransferase 4
sialyltransferase 4
CDR 4
sialyltransferase 4
polo-like kinase 1 4
glutamate dehydrogenase 4
GMP synthase 4
tryptophan hydroxylase 4
PRA 3
2',3'-cyclic nucleotide phosphohydrolase 3
glutathione reductase 3
nitrate reductase 3
pyruvate carboxylase 3
nitrate reductase 3
cellobiohydrolase 3
glutamate decarboxylase 3
azoreductase 3
nitrate reductase 3
nitrate reductase 3
nitrate reductase 3
chondroitinase 3
acyl carrier protein synthase 3
CPL 3
phosphoamidase 3
tryptophanase 3
glutamate dehydrogenase 3
lactic acid dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
alpha-L-fucosidase 3
carboxypeptidase Y 3
methionyl-tRNA synthetase 3
oxalate oxidase 3
more...
Compound
cAMP 4820
AMP 2862
cGMP 2848
calcium 2537
Dec 1312
nitric oxide 1177
DNA 1051
GMP 970
sodium 949
phosphate 752
ATP 731
Clin 672
oxygen 576
glucose 490
arginine 462
Sildenafil 457
prostacyclin 403
GTP 403
ADP 397
water 390
caffeine 375
ADP 348
ADP 340
acetate 307
prostaglandin E1 294
Cardiol 278
potassium 273
Theophylline 272
adenylate 264
Forskolin 240
noradrenaline 230
Mg2+ 225
DEAE 212
sulfate 199
tyrosine 187
PGE2 167
glutamate 154
TNF 154
glycerol 153
Isoproterenol 147
hydrogen 143
salt 140
SDS 139
manganese 138
Adenosine 138
Phe 136
serine 128
zinc 128
EDTA 127
EDTA 126
Milrinone 123
leucine 118
His 114
GDP 113
5-HT 112
alanine 108
Insulin 107
ethanol 105
Pentoxifylline 103
nitrate 101
ammonium 98
Triton X-100 98
NAD 97
bromide 96
nitrogen 95
cysteine 92
galactose 91
lysine 85
methionine 85
threonine 84
PGE 82
urea 80
8-Br-cGMP 79
pyrimidine 71
pyrimidine 71
pyridine 70
phosphorus 69
Papaverine 68
iron 68
ICI 68
NAD 67
ACh 66
PEG 62
Adrenal 60
nicotinamide 59
CO2 59
ACTH 59
nonyl 59
ADP-ribose 58
cobalt 56
copper 55
Histamine 55
H2O2 54
GABA 52
aldosterone 52
Dopamine 52
PMA 52
tryptophan 52
GABA 52
4-methoxybenzyl 51
CaCl2 49
PMA 49
HCl 49
uridine 49
TSH 49
tryptophan 48
2-imidazolidinone 48
PEG 48
Norepinephrine 47
tryptophan 47
tryptophan 47
cadmium 46
Indomethacin 45
Asp 45
CPT 44
CPT 44
iodine 43
NMDA 43
Glucagon 43
COS 43
creatinine 42
Carbachol 41
cyclopentyl 41
NH2 41
Dibutyryl cyclic AMP 40
Dibutyryl cyclic AMP 40
methanol 39
PAS 38
Propranolol 38
Propranolol 38
NADH 37
retinoic acid 37
Retinal 37
acetic acid 37
Dipyridamole 36
Aminophylline 36
Dipyridamole 36
Dipyridamole 36
Dipyridamole 36
isoquinoline 35
Phosphatidylinositol 34
glutamine 34
DMSO 33
ACS 33
Guo 33
GSH 33
GSH 33
TMP 33
acetonitrile 33
NPP 32
carbonate 32
ACS 32
H2S 30
1H-imidazole 30
UTP 30
proline 30
NADPH 30
dipropyl 30
NADPH 29
Gly 29
Testosterone 28
TOF 28
hydroxylamine 28
Testosterone 28
Dobutamine 28
MEK 27
PPi 27
THP 26
Tris 26
ammonia 26
acrylamide 25
Nifedipine 25
MTT 25
vitamin D 25
DOS 24
Guo 24
Dexamethasone 24
BRL 24
hydroxylamine 24
CMP 24
PGD2 23
Salbutamol 23
Cycloheximide 23
THP 23
PAH 23
CMP 23
MDA 23
MAP 23
AMPA 23
hexose 22
hexose 22
phosphoric acid 22
CoA 22
cyanide 22
hexose 22
hexose 22
phenol 22
piperazine 21
TPA 21
TPA 21
Tris 21
Ang II 21
Phorbol 21
A 42 21
quinoline 20
Vasopressin 20
Lead 20
Atropine 20
aspartic acid 20
quinoline 20
Optimal 20
Methylene blue 19
tetraphosphate 19
Trifluoperazine 19
Verapamil 19
MgCl2 19
Angiotensin II 19
fluorine 19
Cereb 19
CTX 19
Verapamil 19
ASA 19
alloxan 19
asparagine 18
CTP 18
Progesterone 18
gamma-aminobutyric acid 18
benzoic acid 18
Diabetol 18
FAD 18
NADP 18
octyl 17
aluminum 17
H2S 17
octyl 17
TEA 17
Ouabain 17
octyl 17
DEA 17
silver 17
DEA 17
superoxide radical 17
TEA 17
Thrombin 17
DEA 17
piperidine 17
PPI 17
piperidine 17
butyric acid 16
quinazoline 16
Salt 16
nicotinic acid 16
PAP 16
alcohol dehydrogenase 16
PAP 16
Secretin 16
Triton 16
quinazoline 16
Neuronal 15
dUTP 15
Genistein 15
hydroxide 15
Chlorpromazine 15
TCA 15
2-methylpiperazine 15
Collagen 15
3'-AMP 15
Off 15
nickel 15
trimethyllysine 15
GlcNAc 15
Ile 15
Estradiol 15
Glibenclamide 14
aspartic acid 14
acetamide 14
acetamide 14
Adenine 14
aldehyde 14
acetone 14
pyrazine 14
Prostaglandin 14
Prostaglandin 14
L-DOPA 14
nicotinic acid 14
aspartic acid 14
butyric acid 14
FK506 14
aspartic acid 14
UDP 14
CDP 14
naphthalene 14
benzamide 14
PLA 14
palmitic acid 14
HCO 14
PAP 13
SQ 20009 13
PNP 13
prostaglandin F2alpha 13
guanidine 13
formic acid 13
AEA 13
PAP 13
Phorbol 12-myristate 13-acetate 13
formic acid 13
Okadaic acid 13
formic acid 13
Lithium 13
Bradykinin 13
nicotinic acid 13
formic acid 13
formic acid 13
formic acid 13
formic acid 13
formic acid 13
DETA 13
4-nitrophenyl 13
FMN 13
Trypsin 13
more...