Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.4.1 (
phosphodiesterase
)
18,767
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
phosphodiesterase
0.956
nucleotide pyrophosphatase
0.026
PDE4
0.018
PDE
0.017
cyclic nucleotide phosphodiesterase
0.013
AMP
0.010
exonuclease I
0.009
PDE5
0.009
adenylate cyclase
0.008
cyclic AMP phosphodiesterase
0.008
PDE2
0.006
cGMP phosphodiesterase
0.005
PDE4B
0.003
PDE4A
0.003
guanylate cyclase
0.003
Phosphodiesterase
0.003
cGMP-PDE
0.003
calmodulin
0.002
adenylyl cyclase
0.002
GMP
0.002
more...
Disease
PDE
0.016
erectile dysfunction
0.008
pulmonary hypertension
0.001
Pulmonary arterial hypertension
0.001
SCAN1
0.001
cholera
0.000
chronic obstructive pulmonary disease
0.000
heart failure
0.000
premature ejaculation
0.000
pertussis
0.000
asthma
0.000
sexual dysfunction
0.000
right heart failure
0.000
hypertension
0.000
NAME
0.000
acrodysostosis
0.000
congestive heart failure
0.000
persistent pulmonary hypertension of the newborn
0.000
atopic dermatitis
0.000
Hyperdynamic septic shock
0.000
more...
Symptom
Lower urinary tract symptoms
0.000
Ureteric colic
0.000
flushing
0.000
Central cyanosis
0.000
nasal congestion
0.000
Muscle fibrosis
0.000
headache
0.000
starvation
0.000
nausea
0.000
vomiting
0.000
hyperoxia
0.000
dyspnea
0.000
diarrhea
0.000
Hangover
0.000
astasia
0.000
memory loss
0.000
spasm
0.000
bitter taste
0.000
pain
0.000
ataxia
0.000
more...
Drug
Rolipram
0.011
Cilostazol
0.004
Vardenafil
0.003
Viagra
0.003
Roflumilast
0.003
Roflumilast
0.003
Enoximone
0.002
CIA
0.002
Viagra
0.002
Forskolin
0.001
Cilomilast
0.001
Amrinone
0.001
Levitra
0.001
Theophylline
0.001
Levitra
0.001
Pimobendan
0.001
Ibudilast
0.001
Papaverine
0.001
Avanafil
0.000
Piclamilast
0.000
more...
Enzyme
phosphodiesterase
1.000
PDE
0.033
exonuclease I
0.011
cGMP phosphodiesterase
0.009
adenylate cyclase
0.009
nucleotide pyrophosphatase
0.005
guanylate cyclase
0.004
protein kinase
0.002
PKG
0.001
3'-exonuclease
0.001
5'-nucleotidase
0.001
lysophospholipase D
0.001
AMPK
0.001
3'-phosphatase
0.000
glycerophosphocholine cholinephosphodiesterase
0.000
venom phosphodiesterase
0.000
glycerophosphocholine phosphodiesterase
0.000
AcpH
0.000
protein kinase C
0.000
rhodopsin kinase
0.000
more...
Compound
cAMP
0.021
cGMP
0.021
Sildenafil
0.011
AMP
0.010
GMP
0.005
Milrinone
0.003
Theophylline
0.001
Forskolin
0.001
calcium
0.001
nitric oxide
0.001
2-imidazolidinone
0.001
Pentoxifylline
0.001
prostaglandin E1
0.001
prostacyclin
0.001
adenylate
0.001
Papaverine
0.001
8-Br-cGMP
0.001
SQ 20009
0.000
4-methoxybenzyl
0.000
caffeine
0.000
more...