Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.4.1 (phosphodiesterase)
 18,767 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PDE4C-delta54 10.7
PDE4B5 10.7
sema domain, transmembrane domain 10.7
triphosphoinositide phosphodiesterase 10.7
alanyl-tRNA synthetase domain containing 1 10.7
guanylate cyclase 1, soluble, beta 3 10.7
PDE8A protein 10.7
PDE7B protein 10.7
CGS-PDE 10.7
TRBV6-2 10.7
ADP-ribosylation factor interacting protein 1 10.7
ectonucleotide pyrophosphatase/phosphodiesterase 6 10.7
phospholipase A2, group VII 10.7
inositoltrisphosphohydrolase 10.7
transmembrane channel-like 7 10.7
Hcam3 10.7
PDE1A5 10.7
DPDE2 10.7
TRBV6-3 10.7
PDE4C-delta109 10.7
more...
Disease
Hyperdynamic septic shock 10.7
Primary apnoea 10.7
SCAN1 9.9
organic sexual dysfunction 9.7
PDE 9.2
Mietens' syndrome 8.7
Gastric mucosal lesion 8.7
Drug-induced sexual dysfunction 8.7
LCA4 8.7
Nonarteritic anterior ischemic optic neuropathy (NAION) 8.0
erectile dysfunction 7.9
acrodysostosis 7.9
GACI 7.9
Toxic optic neuropathy 7.9
RP26 7.6
Neuroleptic-induced tardive dyskinesia 7.6
Portopulmonary hypertension 7.5
female sexual arousal disorder 7.4
Pulmonary arterial hypertension 7.3
Radiation esophagitis 7.1
more...
Symptom
Ureteric colic 8.7
Central cyanosis 7.7
Muscle fibrosis 7.4
Lower urinary tract symptoms 7.1
Hangover 5.1
nasal congestion 4.9
astasia 4.8
Urinary symptoms 4.5
skin pain 4.5
Periodic breathing 4.3
Visual symptoms 3.9
flushing 3.8
photopsia 3.7
nocturnal polyuria 3.5
No adverse effect 3.4
bitter taste 3.3
Spastic 3.3
Decreased activity 3.3
pachyonychia 3.2
retching 3.2
more...
Drug
Quazinone 10.7
Piclamilast 10.4
Piclamilast 10.4
Indolidan 10.2
Rolipram 10.2
Cilomilast 10.1
Avanafil 10.1
Roflumilast 10.0
Roflumilast 10.0
Vardenafil 9.8
Levitra 9.8
Enoximone 9.8
2-Fluoroadenosine 9.7
R-Rolipram 9.7
Ibudilast 9.6
Piroximone 9.5
Levitra 9.5
Cilostazol 9.4
Pimobendan 9.4
Warfarin potassium 9.1
more...
Enzyme
phosphodiesterase 10.7
mannosylphosphodolichol phosphodiesterase 10.7
exonuclease I 10.6
yeast ribonuclease 10.1
AcpH 10.1
glycerophosphocholine cholinephosphodiesterase 10.0
nucleotide pyrophosphatase 9.8
exoribonuclease H 9.7
cGMP phosphodiesterase 9.5
PDE 9.4
CMP-sialic acid hydrolase 9.4
glycerophosphocholine phosphodiesterase 9.3
dTMPase 9.1
cytochrome c methyltransferase 9.1
aminopeptidase S 9.1
EC 2.7.7.53 8.9
EC 4.1.1.46 8.7
EC 3.6.1.29 8.6
cytidylate cyclase 8.6
lysophospholipase D 8.5
more...
Compound
N-neopentylacetamide 10.7
C19H16O3 10.7
8-Bromoinosine 10.7
C19H16O3 10.7
1-ethyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione 10.7
C19H16O3 10.7
Linderane 10.7
C22H30N6 10.7
C19H16O3 10.7
Leniquinsin 10.7
Cytosine arabinoside monophosphate 10.7
C19H16O3 10.7
C19H16O3 10.7
Olprinone hydrochloride 10.7
N-(3,4-dimethoxyphenyl)acetamide 10.7
SQ 20009 10.0
Dehydroheliotridine 9.7
C16H16O3 9.7
Atherosperminine 9.7
2-Fluoroadenosine 9.7
more...