Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.31.1 (micrococcal nuclease)
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Human Gene/Protein
zinc finger protein 292 13.5
FLJ35220 protein 13.5
HP1-BP74 13.5
Non-histone chromosomal protein 12.5
putative ubiquitin-protein ligase 12.5
ETL1 11.9
H2A-Bbd 11.9
NOP5 11.5
RRP2 11.1
G3BP protein 10.9
TSN 10.7
PSMD6 10.7
Tudor domain-containing protein 3 10.5
Exp4 10.3
H2B.2 10.3
Phospholipase D4 10.3
HILS1 10.1
RRP1 10.1
DNase II 10.1
H2A.Bbd 10.1
HSS1 10.0
CRYBP1 10.0
WHSC2 10.0
E1A-F 10.0
H2B.1 9.8
phospholipase D3 9.7
CREB3L3 9.7
HMG14 9.7
heat shock factor binding protein 1 9.5
HMG-17 9.4
SND1 9.4
UBTF 9.4
NHCP2 9.4
deoxyribonuclease I 9.3
NELF-A 9.3
Proline-, glutamic acid- and leucine-rich protein 1 9.3
H-l 9.1
PE-1 9.0
ATP synthase subunit 9 8.9
MN1 8.9
CEP1 8.9
Micrococcus luteus UV endonuclease 8.9
FIST 8.8
KMT1A 8.8
SRp38 8.8
HMG2 8.8
histone H1 8.8
linker histone 8.7
SPOC1 8.7
deoxyribonuclease II 8.7
Ribonuclease P 8.7
DNaseI 8.7
DNase I 8.6
H2A.2 8.6
DNA topoisomerase 1 8.6
SMARCD1 8.6
DBR1 8.6
GRF2 8.6
HELLS 8.5
histone protein 8.5
H2A 8.4
H2B 8.4
parathymosin 8.4
Exonuclease III 8.3
C4A4 8.3
mutant beta-globin 8.3
cyclophilin C 8.3
UBC2 8.3
SLBP 8.3
CEN3 8.3
hepatocyte nuclear factor 1 alpha 8.2
TTF-I 8.2
ACCA 8.2
2'-phosphodiesterase 8.1
UBAP1 8.1
glucocorticoid-induced TNFR-related protein 8.1
epsilon globin 8.1
non-histone chromosomal protein 8.1
HMGB3 8.1
nuclear pore complex protein 8.1
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Disease
ADLTE 9.8
TNH 9.8
Flavivirus infection 8.9
Camelpox 8.3
Takahara 8.0
Staphylococcal food poisoning 7.8
MPE 7.6
CMCT 7.6
DBM 7.2
Other variants 7.1
IgA myeloma 6.7
Dressler 6.6
GDD 6.4
Photosensitization 6.3
CCA1 6.1
Friend leukemia 6.1
HS3 6.0
sclerodactyly 6.0
PHS 5.8
RPC 5.8
erythroleukemia 5.7
CREST 5.6
HML 5.5
EMC 5.4
Fox 5.3
CLN1 5.2
myeloblastosis 5.1
presenile dementia 5.1
ST8 5.1
Superinfection 5.0
CLN2 4.9
Wolf-Hirschhorn syndrome 4.9
Pick's disease 4.8
xeroderma pigmentosum 4.8
esophageal dysmotility 4.7
Staphylococcus aureus bacteremia 4.7
Leydig cell tumor 4.7
SCP 4.6
CP1 4.6
HP1 4.5
CAA 4.5
immune disorder 4.4
Classical swine fever 4.4
CJD 4.4
Cockayne syndrome 4.3
LIS1 4.3
MRSA 4.2
GCT 4.2
Farber 4.1
CAA 4.1
Goldblatt 4.1
mammary tumor 4.1
mastitis 4.0
Haas 4.0
RP4 4.0
HMR 4.0
TTP 3.9
scrapie 3.9
Plasmodium falciparum infection 3.9
Dissociation 3.9
CAN 3.8
lymphosarcoma 3.8
pyoderma 3.7
PDE 3.7
MSD 3.7
XPD 3.7
Mastitis 3.7
acute monocytic leukemia 3.7
staphylococcal infection 3.7
hidradenitis 3.7
calcinosis 3.7
MAR 3.7
Raynaud's phenomenon 3.6
African swine fever 3.6
vaccinia 3.6
staphylococcus 3.5
DMS 3.5
hepatitis D 3.5
BLM 3.5
toxic shock syndrome 3.4
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Symptom
autodigestion 6.7
general problem 3.7
starvation 2.3
collapse 2.2
splenomegaly 1.2
acidity -0.4
hypothermia -0.6
diarrhea -2.3
Drug
DNase I 8.6
Crotonaldehyde 7.8
Neocarzinostatin 7.7
Potassium sorbate 7.5
ROX 7.2
Guanidine 7.1
Guanidine 7.1
Lysostaphin 7.1
RBT 6.3
CrCl3 5.9
Pronase 5.1
Cibacron Blue 4.6
Papain 4.3
ZnCl2 4.1
ZnCl2 4.1
PDL 4.1
Phosphatidylserine 4.1
-deoxyadenosine 4.0
Riboflavin 3.9
lysine 3.6
CTC 3.4
G418 3.3
Gel 3.3
Fraction 3.1
CTC 3.1
ETS 3.1
CTA 3.0
Amiloride 2.9
MIL 2.8
Biopolymers 2.7
Amiloride 2.6
Asn 2.5
CaCl2 2.4
CaCl2 2.4
ACT 2.4
CaCl2 2.4
Glycerol 2.3
TMS 2.3
NH3 2.3
Forskolin 2.1
IFN-beta 1.9
Vitamin A 1.9
MRC 1.7
HCH 1.7
Glutathione 1.1
Bifidobacterium 0.9
ROC 0.5
EE2 0.5
MAP 0.5
THF 0.5
ABC 0.4
nitroglycerin 0.3
ROS 0.2
NADH 0.0
lactose -0.6
ampicillin -0.6
caffeine -0.9
Leaf -0.9
ascorbate -1.0
IL-2 -1.4
CSF -1.5
Dermatol -3.5
Enzyme
micrococcal nuclease 13.5
3'-exonuclease 11.6
NMN glycohydrolase 10.7
venom phosphodiesterase 10.1
DNase II 9.7
3-methyladenine DNA glycosylase I 9.4
staphopain 9.0
Escherichia coli exonuclease III 8.9
aureolysin 8.9
polynucleotide kinase 8.5
dCMP hydroxymethylase 8.2
DNase 8.1
phosphoribosylanthranilate isomerase 7.7
deoxyribonuclease 7.3
p100 7.2
RNase P 7.2
deoxyribonuclease 7.1
3'-phosphatase 7.1
S1 nuclease 6.8
alpha-sarcin 6.7
lysostaphin 6.6
nicotinamide mononucleotide adenylyltransferase 6.5
signal peptidase II 6.4
RNA ligase 6.4
endodeoxyribonuclease 6.4
endonuclease V 6.3
pseudouridine synthase 6.2
PPDK 6.2
HtrA 6.0
polynucleotide phosphorylase 6.0
carboxypeptidase G2 6.0
RNase H 5.9
proteinase K 5.9
endonuclease 5.8
lambda exonuclease 5.8
poly(ADP-ribose) glycohydrolase 5.8
RNase 5.7
aminopeptidase B 5.7
aspartyl-tRNA synthetase 5.6
AP lyase 5.6
NCP 5.5
histone acetyltransferase 5.5
RNase T1 5.2
RNase 5.1
ribonuclease 5.1
Fpg protein 5.1
ribonuclease 5.0
exoribonuclease 4.9
RNA polymerase 4.9
endoproteinase Glu-C 4.7
NAD glycohydrolase 4.7
topoisomerase 4.7
SCP 4.6
proton-translocating ATPase 4.6
topoisomerase 4.6
DNA polymerase 4.6
MAT 4.5
C3 convertase 4.5
cystathionine gamma-lyase 4.4
DNA ligase 4.4
DNA ligase 4.4
thromboxane synthase 4.3
MAT 4.3
galactokinase 4.2
DNA methyltransferase 4.2
tyrosine aminotransferase 4.1
BAL 4.1
poly(A) polymerase 4.1
enterokinase 4.1
AMP deaminase 4.0
adenine phosphoribosyltransferase 4.0
cytochrome c peroxidase 4.0
deoxycytidine kinase 4.0
dihydrofolate reductase 4.0
pullulanase 3.9
isoamylase 3.9
ClpP 3.9
trypsin 3.9
peptidyl-prolyl cis-trans isomerase 3.9
lysozyme 3.8
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Compound
1,3-dibromo-2-propanol 10.7
593A 10.7
2-Methoxyaniline 10.3
Methyl alpha-D-glucopyranoside 10.1
GANU 10.1
GANU 9.8
Phosphoglycolate 9.6
A 186 9.6
Trimethylpsoralen 9.3
PTMS 8.9
Echinomycin 8.6
MPE 8.5
NMHE 8.3
Methyl green 8.3
chloric acid 8.2
chloric acid 8.1
Novex 8.1
Nafoxidine 7.9
Epichlorohydrin 7.9
Neocarzinostatin 7.7
N6-Methyladenosine 7.5
chloroacetonitrile 7.4
DBM 7.3
DBM 7.2
Cesium chloride 7.2
N-ethylurea 7.1
methyl hydrogen 7.1
methyl hydrogen 7.0
Potassium sorbate 7.0
CHNO 7.0
Phthalocyanine 7.0
trichloroacetonitrile 6.9
TNB 6.8
Psoralen 6.8
Potassium permanganate 6.8
dGMP 6.7
2-butenal 6.6
Aphidicolin 6.6
Aphidicolin 6.6
Sucralose 6.6
HMBA 6.6
DMS 6.5
Pseudouridine 6.3
Trimethylamine N-oxide 6.3
NMN 6.3
dichloroacetonitrile 6.2
Chlorate 6.2
DAMP 6.2
HMBA 6.1
Histone 6.1
CUE 6.0
Aldol 6.0
3-aminobenzamide 5.9
7-methylguanosine 5.8
8-hydroxyguanosine 5.8
Mithramycin 5.8
1,3-dioxane 5.8
MgCl2 5.7
SPD 5.7
F23 5.7
Berenil 5.7
EMC 5.7
guanidine 5.6
MGBG 5.5
MGBG 5.5
ADP-ribose 5.5
O,O-diethyl 5.5
HBC 5.5
40S 5.5
Novobiocin 5.4
S 1 5.4
mercaptoacetic acid 5.4
N-hydroxysuccinimide ester 5.3
Leupeptin 5.3
MnO4 5.3
Carcinogen 5.3
Deoxyribonucleic acid 5.2
DNP 5.2
ACNU 5.1
Puromycin 5.0
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