Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.31.1 (
micrococcal nuclease
)
2,818
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The influence of erythrocytes of different blood groups on the intestinal isoenzyme of alkaline phosphatase (
EC 3.1.31.1
) was investigated. Binding of the enzyme to erythrocyte membranes was demonstrated by sedimentation experiments, by enzyme electrophoresis, by gel chromatography and immunologically using a modified Coombs technique. We found that red cells of blood group A bind almost all
intestinal alkaline phosphatase
; erythrocytes of blood group B or O to a much lesser degree. This is in accordance with the fact that
intestinal alkaline phosphatase
is found more frequently in the serum of individuals of blood group O or B than in serum of persons of blood group A. We conclude that underlying the described blood group dependent differences in synthesis of
intestinal alkaline phosphatase
lies a mechanism involved in the regulation of the activity of
intestinal alkaline phosphatase
in human serum.
...
PMID:Intestinal alkaline phosphatase and the ABO blood group system--a new aspect. 744 39
