Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.31.1 (micrococcal nuclease)
 2,818 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Immunoblot analysis using antibody specific to yeast ras-related protein Yp20 revealed a 21kDa protein associated with HeLa cell chromatin which immunologically cross-reacted with this ras-related protein. The 21kDa protein can be rapidly released from the HeLa nuclei by micrococcal nuclease digestion. It seems to be associated with long mononucleosomes as determined by separation of chromatin subunits on sucrose gradients. We suggest that the 21kDa HeLa protein may be the human homologue of yeast Yp20.
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PMID:Nuclear proteins from HeLa cells are immunoreactive with anti-yeast Yp20 ras related antibodies. 233 23