Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.30.2 (
endonuclease
)
18,621
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
endonuclease
18601
Mol
2039
Sep
1233
Gen
474
ATP
399
DNA polymerase
376
tRNA
338
polypeptide
323
methyltransferase
287
deoxyribonuclease
281
APE1
228
helicase
224
DNase I
213
ATPase
193
DNase
182
p53
181
SDS
178
Pseudomonas
173
XPF
172
histone
172
DNA ligase
168
fused
167
RNase
160
ERCC1
150
thymus
142
DNA methyltransferase
137
pol
115
telomeric
112
RNase III
109
proliferating cell nuclear antigen
106
dimeric
105
ribonucleoprotein
102
mer
99
beta-globin
99
NMR
95
caspase-3
95
Dicer
94
Pol
94
endonuclease III
94
zinc finger
93
RNase H
92
thymidine kinase
91
glycoprotein
90
phosphodiesterase
87
DNA polymerase beta
84
interferon
82
IIS
79
endoplasmic reticulum
79
ADP
77
integrase
75
Polymerase
75
lymphoid
74
phosphatase
73
GATC
69
SWI
68
XPG
68
insulin
67
cryptic
67
RNase E
67
FEN1
67
MF1
66
RNA polymerase II
65
flap endonuclease 1
65
Rad51
64
gag
64
Rad50
63
ORF
62
uracil-DNA glycosylase
61
phosphorylating
61
K12
60
A-T
59
c-myc
58
DNA repair enzyme
58
DNA-dependent protein kinase
58
Boc
57
DNA helicase
57
membrane protein
57
ATM
57
MUS81
56
SOD
55
more...
Disease
cancer
734
tumor
422
herpes simplex
221
influenza
219
leukemia
179
SDS
178
XPF
175
plaque
152
Mycobacterium
145
Haemophilus
144
carcinogenesis
141
thalassemia
134
xeroderma pigmentosum
131
HIV
113
tuberculosis
93
immunodeficiency
92
cytomegalovirus
87
ATM
87
hepatocellular carcinoma
76
Mycoplasma
75
AIDS
73
carcinoma
73
virus infection
72
anemia
71
infectious diseases
68
tumorigenesis
68
XPG
68
diabetes
66
Klebsiella
62
cholera
61
breast cancer
60
cold
60
vaccinia
58
pneumonia
51
Infection
51
lung cancer
50
Epstein
47
Chlamydia
47
parvovirus
45
varicella
43
adenocarcinoma
43
BLM
43
Fanconi
42
suicide
40
lymphoma
40
Yersinia
39
myeloblastosis
39
coronary artery disease
38
sarcoma
38
malaria
38
sickle cell disease
37
Cockayne syndrome
36
hepatitis B
36
ischemia
35
abortion
35
atherosclerosis
33
Adenovirus
33
systemic lupus erythematosus
32
multiple myeloma
32
melanoma
32
West
32
Legionella
30
herpes
29
cystic fibrosis
29
gastroenteritis
29
Alzheimer's disease
29
tumor progression
28
hepatitis C
28
meningitis
27
TEM
27
TEM
26
MCF
26
skin cancer
26
HML
26
hypertension
25
ovarian cancer
25
glioma
24
colorectal cancer
24
colon cancer
24
pheochromocytoma
24
more...
Symptom
diarrhea
57
collapse
40
starvation
23
DNA marker
11
autodigestion
11
weakness
10
erythema
8
ataxia
8
pain
6
acidity
5
splenomegaly
5
seizures
4
headache
4
respiratory distress
3
nausea
3
fatigue
3
skin damage
3
hyperoxia
3
pallor
3
dyspnea
3
hypothermia
3
hepatosplenomegaly
3
functional recovery
2
abdominal pain
2
masculinization
2
dry eye
2
vomiting
2
Spots
2
anorexia
2
cerebellar ataxia
2
myalgia
2
angina
2
memory loss
2
stigma
2
syncope
2
polyuria
1
discomfort
1
Ill
1
rhinorrhea
1
pleuritic chest pain
1
microbial colonization
1
chorea
1
adenitis
1
exhaustion
1
ACHE
1
astasia
1
eds
1
paraparesis
1
agitation
1
constipation
1
ophthalmoplegia
1
hepatomegaly
1
lethargy
1
Inflammatory pain
1
sore throat
1
incoordination
1
discomfort
1
Involuntary Movement
1
acute stress
1
dysarthria
1
hypotonia
1
arthralgia
1
nasal discharge
1
spasticity
1
dystonia
1
penile lesion
1
hypocapnia
1
overweight
1
bitter taste
1
emaciation
1
chills
1
paresthesia
1
Drug
DNase I
216
ampicillin
120
lysine
108
Gel
65
Dermatol
60
Mutagen
33
Asn
33
BLM
30
Fragment
26
caffeine
24
ROS
21
-deoxyadenosine
19
CaCl2
19
CaCl2
19
CaCl2
19
G418
18
lactose
18
AGG
15
IL-2
14
ZnCl2
13
ZnCl2
13
TTC
12
FLP
12
NH3
10
Kenyan
10
Nephron
10
NADH
9
Bifidobacterium
9
IFN-gamma
8
nitroglycerin
8
CSF
8
Alanine
8
ABC
7
CTT
6
ETS
6
NAH
5
Leaf
5
AraC
5
Biopolymers
5
ascorbate
5
PMEA
5
Etoposide
5
IFN-beta
5
Growth hormone
5
Fraction
5
TAT
5
NAG
5
Growth hormone
5
Itraconazole
4
PTC
4
Pronase
4
CoCl2
4
CoCl2
4
CTX
4
Ethanol
4
CTC
4
CTC
4
ISP
4
CTA
3
ID2
3
CED
3
RFP
3
Galactose
3
Glycerol
3
MDS
3
Adriamycin
3
Sinefungin
3
TAC
3
ACT
3
VCR
3
MgSO4
2
FAD
2
Deoxyadenosine
2
Fludarabine
2
MOF
2
Moxifloxacin
2
Ranitidine
2
Fluorescein
2
Taxol
2
Cardiovasc
2
more...
Enzyme
endonuclease
18621
DNA polymerase
589
DNase
383
DNA methyltransferase
297
RNA polymerase
294
reverse transcriptase
285
RNase
261
RNase
249
DNA ligase
248
DNA ligase
247
ATPase
201
deoxyribonuclease
158
phosphodiesterase
149
restriction-modification system
134
S1 nuclease
133
topoisomerase
127
topoisomerase
118
RNase H
104
RNase III
97
beta-lactamase
93
micrococcal nuclease
91
ribonuclease
91
thymidine kinase
91
ribonuclease
89
deoxyribonuclease
89
RNase P
84
caspase-3
83
protein kinase
83
AP lyase
78
transcriptase
76
beta-galactosidase
63
PARP
62
alkaline phosphatase
61
polynucleotide kinase
61
3'-exonuclease
59
DNase II
58
catalase
54
endodeoxyribonuclease
48
MAT
48
luciferase
48
MAT
47
superoxide dismutase
47
endonuclease VII
47
ACS
46
peroxidase
45
endonuclease V
41
proteasome
39
trypsin
39
proteinase K
36
neuraminidase
33
Fpg protein
33
Escherichia coli exonuclease III
32
dihydrofolate reductase
31
exoribonuclease
31
ERK
31
protein kinase C
30
PRE
29
venom phosphodiesterase
29
lambda exonuclease
29
tRNase Z
29
splicing endonuclease
28
lactate dehydrogenase
27
chloramphenicol acetyltransferase
26
RNA ligase
25
3'-phosphatase
24
RNase T1
24
thymidylate synthase
23
polynucleotide phosphorylase
23
lysozyme
22
glutathione S-transferase
21
ribonucleotide reductase
21
mitogen-activated protein kinase
21
21-hydroxylase
20
CAD
18
CAD
18
ribonucleotide reductase
18
CAD
18
phosphoglycerate kinase
17
BAL
17
violaxanthin de-epoxidase
16
more...
Compound
DNA
13000
Dec
1363
Clin
564
phosphate
487
Mg2+
446
calcium
426
ATP
399
pyrimidine
369
pyrimidine
368
oxygen
284
sodium
270
zinc
269
water
260
His
202
SDS
201
hydrogen
198
salt
182
sulfate
182
manganese
182
bromide
174
alanine
170
lysine
167
arginine
152
tryptophan
144
cysteine
130
EDTA
123
Asp
122
EDTA
121
methionine
116
tyrosine
109
leucine
108
methyl methanesulfonate
104
DEAE
104
H2O2
87
glucose
87
serine
86
MgCl2
78
ADP
78
ADP
77
ADP
77
ammonium
75
glycerol
73
threonine
69
nitrogen
68
iron
66
GTP
66
silver
63
adenosylmethionine
62
galactose
62
urea
62
Phe
61
copper
56
phenol
55
tryptophan
54
uridine
54
NH2
51
dUTP
51
tryptophan
50
acetate
50
tryptophan
50
NAD
47
ACS
46
ACS
46
cobalt
45
PEG
44
Tris
44
Gly
43
acrylamide
43
Tris
42
ethanol
41
AMP
41
dATP
40
Agarose
39
valine
38
nitric oxide
38
HCl
38
BLM
38
iodine
36
TEM
35
PAM
35
more...