Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.30.2 (endonuclease)
 18,621 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
endonuclease 18601
Mol 2039
Sep 1233
Gen 474
ATP 399
DNA polymerase 376
tRNA 338
polypeptide 323
methyltransferase 287
deoxyribonuclease 281
APE1 228
helicase 224
DNase I 213
ATPase 193
DNase 182
p53 181
SDS 178
Pseudomonas 173
histone 172
XPF 172
DNA ligase 168
fused 167
RNase 160
ERCC1 150
thymus 142
DNA methyltransferase 137
pol 115
telomeric 112
RNase III 109
proliferating cell nuclear antigen 106
dimeric 105
ribonucleoprotein 102
beta-globin 99
mer 99
caspase-3 95
NMR 95
Dicer 94
endonuclease III 94
Pol 94
zinc finger 93
RNase H 92
thymidine kinase 91
glycoprotein 90
phosphodiesterase 87
DNA polymerase beta 84
interferon 82
IIS 79
endoplasmic reticulum 79
ADP 77
integrase 75
Polymerase 75
lymphoid 74
phosphatase 73
GATC 69
SWI 68
XPG 68
FEN1 67
cryptic 67
insulin 67
RNase E 67
MF1 66
RNA polymerase II 65
flap endonuclease 1 65
Rad51 64
gag 64
Rad50 63
ORF 62
phosphorylating 61
uracil-DNA glycosylase 61
K12 60
A-T 59
c-myc 58
DNA-dependent protein kinase 58
DNA repair enzyme 58
DNA helicase 57
Boc 57
membrane protein 57
ATM 57
MUS81 56
SOD 55
E.coli 54
env 54
nucleotide pyrophosphatase 52
DNA-binding domain 52
GTP 52
cytokine 52
alkaline phosphatase 51
Chlamydomonas 51
DNase II 50
APE 50
3'-5' exonuclease 48
AP lyase 48
MAT 47
ACS 46
Msp 46
PARP 46
hemoglobin 45
unknown function 45
AMP 45
hOGG1 45
poly(ADP-ribose) polymerase 45
H2AX 44
HLA 43
PB1 42
catalase 42
ras 42
OGG1 41
RAD52 41
UTR 41
X-linked 40
superoxide dismutase 40
HAP1 38
threonine 38
pseudogene 37
MRE11 36
Bcl-2 35
RNA polymerase I 35
DNA-binding protein 35
proteasome 34
lipopolysaccharide 34
ubiquitin 34
cytochrome c 34
RAD51 33
growth hormone 33
ATR 33
peroxidase 33
C-C 33
BRCA1 33
RNase L 32
p21 32
erythroid 32
XPA 32
nuclear protein 32
topoisomerase I 32
ribosomal protein 31
neuraminidase 31
beta globin 31
EME1 31
CCA 31
vitamin D receptor 31
NAD 30
VIII 29
BLM 29
Poly 29
tRNase Z 29
REA 29
H. influenzae 29
D. melanogaster 29
RNase A 29
XRCC1 29
albumin 29
Chk1 29
TdT 28
RAD1 28
DNA polymerase delta 28
collagen 28
CtIP 28
major histocompatibility complex 28
IFN 28
DNA ligase I 27
more...
Disease
cancer 734
tumor 422
herpes simplex 221
influenza 219
leukemia 179
SDS 178
XPF 175
plaque 152
Mycobacterium 145
Haemophilus 144
carcinogenesis 141
thalassemia 134
xeroderma pigmentosum 131
HIV 113
tuberculosis 93
immunodeficiency 92
ATM 87
cytomegalovirus 87
hepatocellular carcinoma 76
Mycoplasma 75
carcinoma 73
AIDS 73
virus infection 72
anemia 71
XPG 68
tumorigenesis 68
infectious diseases 68
diabetes 66
Klebsiella 62
cholera 61
breast cancer 60
cold 60
vaccinia 58
pneumonia 51
Infection 51
lung cancer 50
Epstein 47
Chlamydia 47
parvovirus 45
varicella 43
BLM 43
adenocarcinoma 43
Fanconi 42
suicide 40
lymphoma 40
Yersinia 39
myeloblastosis 39
malaria 38
coronary artery disease 38
sarcoma 38
sickle cell disease 37
Cockayne syndrome 36
hepatitis B 36
ischemia 35
abortion 35
atherosclerosis 33
Adenovirus 33
melanoma 32
systemic lupus erythematosus 32
West 32
multiple myeloma 32
Legionella 30
Alzheimer's disease 29
herpes 29
gastroenteritis 29
cystic fibrosis 29
hepatitis C 28
tumor progression 28
meningitis 27
TEM 27
HML 26
TEM 26
skin cancer 26
MCF 26
ovarian cancer 25
hypertension 25
glioma 24
colon cancer 24
pheochromocytoma 24
colorectal cancer 24
hepatitis 23
RP4 22
erythroleukemia 22
mammary tumor 22
Proteus 21
CEM 21
mastitis 21
Shigella sonnei 21
pseudotuberculosis 20
PIN 20
encephalitis 20
Rous sarcoma 20
prostate cancer 20
Gilbert 20
leishmaniasis 20
PCC 20
HMR 19
cardiovascular disease 19
Huntington's disease 19
WRN 19
conjunctivitis 19
tumor growth 19
acute myeloid leukemia 18
glioblastoma 18
periodontitis 18
PIN 18
respiratory disease 18
laryngotracheitis 18
orf 17
stroke 17
avian sarcoma 17
acute lymphoblastic leukemia 17
Leukemia 17
warts 17
Shiga 17
Marek's disease 17
enteritis 17
plasmacytoma 16
genetic disorder 16
Shigella 16
osteoporosis 16
Bordetella 16
avian influenza 16
rheumatoid arthritis 16
worms 16
PAM 15
Burkitt's lymphoma 15
osteosarcoma 15
squamous cell carcinoma 15
gastric cancer 15
endocarditis 15
IS1 15
Aujeszky's disease 15
SCID 15
arthritis 15
Parkinson's disease 15
retinoblastoma 15
acute promyelocytic leukemia 15
sepsis 14
neuroblastoma 14
stomatitis 14
spotted fever 14
typhoid 14
African swine fever 14
papilloma 14
acute leukemia 14
congenital adrenal hyperplasia 14
malnutrition 14
Brown 14
myocardial infarction 13
bends 13
renal disease 13
chronic myeloid leukemia 13
type 2 diabetes 13
Shigella dysenteriae 13
XPD 13
nosocomial infection 12
abdominal aortic aneurysm 12
avian leukosis 12
growth hormone deficiency 12
more...
Symptom
diarrhea 57
collapse 40
starvation 23
DNA marker 11
autodigestion 11
weakness 10
erythema 8
ataxia 8
pain 6
acidity 5
splenomegaly 5
seizures 4
headache 4
respiratory distress 3
nausea 3
fatigue 3
skin damage 3
hyperoxia 3
pallor 3
dyspnea 3
hypothermia 3
hepatosplenomegaly 3
functional recovery 2
abdominal pain 2
masculinization 2
dry eye 2
vomiting 2
Spots 2
anorexia 2
cerebellar ataxia 2
myalgia 2
angina 2
memory loss 2
stigma 2
syncope 2
polyuria 1
discomfort 1
Ill 1
rhinorrhea 1
pleuritic chest pain 1
microbial colonization 1
chorea 1
adenitis 1
exhaustion 1
ACHE 1
astasia 1
eds 1
paraparesis 1
agitation 1
constipation 1
ophthalmoplegia 1
hepatomegaly 1
lethargy 1
Inflammatory pain 1
sore throat 1
incoordination 1
discomfort 1
Involuntary Movement 1
acute stress 1
dysarthria 1
hypotonia 1
arthralgia 1
nasal discharge 1
spasticity 1
dystonia 1
penile lesion 1
hypocapnia 1
overweight 1
bitter taste 1
emaciation 1
chills 1
paresthesia 1
Drug
DNase I 216
ampicillin 120
lysine 108
Gel 65
Dermatol 60
Asn 33
Mutagen 33
BLM 30
Fragment 26
caffeine 24
ROS 21
CaCl2 19
-deoxyadenosine 19
CaCl2 19
CaCl2 19
G418 18
lactose 18
AGG 15
IL-2 14
ZnCl2 13
ZnCl2 13
TTC 12
FLP 12
Kenyan 10
Nephron 10
NH3 10
NADH 9
Bifidobacterium 9
CSF 8
nitroglycerin 8
IFN-gamma 8
Alanine 8
ABC 7
CTT 6
ETS 6
IFN-beta 5
PMEA 5
ascorbate 5
NAG 5
NAH 5
Leaf 5
AraC 5
Biopolymers 5
TAT 5
Etoposide 5
Growth hormone 5
Fraction 5
Growth hormone 5
Itraconazole 4
ISP 4
Pronase 4
Ethanol 4
CoCl2 4
CTX 4
CoCl2 4
CTC 4
CTC 4
PTC 4
RFP 3
ACT 3
ID2 3
CTA 3
Sinefungin 3
Adriamycin 3
Galactose 3
Glycerol 3
TAC 3
CED 3
MDS 3
VCR 3
Dihydro 2
Taxol 2
TiO2 2
MOF 2
EPA 2
Fluorescein 2
Deoxyadenosine 2
MgSO4 2
Ranitidine 2
MRC 2
Moxifloxacin 2
Fludarabine 2
Protamine sulfate 2
Methylene blue 2
Cardiovasc 2
CAM 2
GRF 2
Fluorescein 2
APD 2
Albumin 2
L-tyrosine 2
CLS 2
Ceftazidime 2
CTX 2
VCR 2
Bortezomib 2
citric acid 2
DM1 2
DEL 2
Neocarzinostatin 2
PTH 2
PDGF B-chain 2
CTX 2
Vitamin B12 2
ENT 2
TEL 2
Monit 2
FAD 2
Adenosine triphosphate 2
EE2 1
NaI 1
Acyclovir 1
Relenza 1
Glutamic acid 1
Sorafenib 1
Parkin 1
ROX 1
Desferal 1
FeCl3 1
DMAP 1
Mycophenolic acid 1
Doxycycline 1
ADR 1
Dakar 1
Retinoic acid 1
Glucantime 1
Cantor 1
MZM 1
Nephron 1
SPP 1
Cerezyme 1
uPA 1
Digenea 1
KAN 1
Ts-1 1
Rhamnose 1
CPT-11 1
Retinoic Acid 1
Parkin 1
Ouabain 1
Heme 1
ARA-C 1
Parlodel 1
Blenoxane 1
Peridex 1
Arsenic trioxide 1
vitamin E 1
Histamine 1
AKM 1
EPI 1
Spectrum 1
Oseltamivir 1
SF6 1
Alliance 1
PCP 1
Vitamin K 1
Salbutamol 1
Clodronate 1
Imatinib 1
ADM 1
more...
Enzyme
endonuclease 18621
DNA polymerase 589
DNase 383
DNA methyltransferase 297
RNA polymerase 294
reverse transcriptase 285
RNase 261
RNase 249
DNA ligase 248
DNA ligase 247
ATPase 201
deoxyribonuclease 158
phosphodiesterase 149
restriction-modification system 134
S1 nuclease 133
topoisomerase 127
topoisomerase 118
RNase H 104
RNase III 97
beta-lactamase 93
micrococcal nuclease 91
thymidine kinase 91
ribonuclease 91
ribonuclease 89
deoxyribonuclease 89
RNase P 84
caspase-3 83
protein kinase 83
AP lyase 78
transcriptase 76
beta-galactosidase 63
PARP 62
polynucleotide kinase 61
alkaline phosphatase 61
3'-exonuclease 59
DNase II 58
catalase 54
luciferase 48
MAT 48
endodeoxyribonuclease 48
superoxide dismutase 47
endonuclease VII 47
MAT 47
ACS 46
peroxidase 45
endonuclease V 41
proteasome 39
trypsin 39
proteinase K 36
Fpg protein 33
neuraminidase 33
Escherichia coli exonuclease III 32
dihydrofolate reductase 31
exoribonuclease 31
ERK 31
protein kinase C 30
venom phosphodiesterase 29
lambda exonuclease 29
PRE 29
tRNase Z 29
splicing endonuclease 28
lactate dehydrogenase 27
chloramphenicol acetyltransferase 26
RNA ligase 25
RNase T1 24
3'-phosphatase 24
polynucleotide phosphorylase 23
thymidylate synthase 23
lysozyme 22
mitogen-activated protein kinase 21
glutathione S-transferase 21
ribonucleotide reductase 21
21-hydroxylase 20
CAD 18
CAD 18
CAD 18
ribonucleotide reductase 18
phosphoglycerate kinase 17
BAL 17
acid phosphatase 16
violaxanthin de-epoxidase 16
focal adhesion kinase 16
exonuclease I 16
glucose-6-phosphate dehydrogenase 15
urease 15
complex I 15
hypoxanthine-guanine phosphoribosyltransferase 15
PAM 15
urease 14
phospholipase D 13
glyceraldehyde-3-phosphate dehydrogenase 12
deaminase 12
cytochrome oxidase 12
DNA 3'-phosphatase 11
APC 11
caspase-1 11
TdT 11
collagenase 11
glucocerebrosidase 11
histone acetyltransferase 11
invertase 10
gamma-glutamyl transpeptidase 10
beta-glucuronidase 10
renin 10
caspase-9 10
neutrophil elastase 9
demethylase 9
alanine aminotransferase 9
alpha-amylase 9
type II restriction enzyme 9
thrombin 9
phenylalanine hydroxylase 8
P-glycoprotein 8
enolase 8
CGT 8
alcohol dehydrogenase 8
chitinase 8
exonuclease V 8
adenine phosphoribosyltransferase 8
dUTPase 8
cellulase 8
lipase 8
glyceraldehyde-3-phosphate dehydrogenase 8
adenosine deaminase 8
ricin 8
nitrogenase 8
MEK 7
firefly luciferase 7
catechol 2,3-dioxygenase 7
HDR 7
poly(A) polymerase 7
ornithine decarboxylase 7
calcineurin 7
transglutaminase 7
citrate synthase 7
AlkA 7
lysin 7
hyaluronidase 7
hyaluronidase 7
xanthine oxidase 7
cdc2 7
glyceraldehyde-3-phosphate dehydrogenase 6
TSP-1 6
tyrosine hydroxylase 6
pyruvate kinase 6
ATP synthase 6
diaphorase 6
ACE 6
glyceraldehyde-3-phosphate dehydrogenase 6
UDP-glucuronosyltransferase 6
adenosine deaminase 6
purine nucleoside phosphorylase 6
STR 6
exonuclease VII 6
rubisco 6
caspase-8 6
glyceraldehyde-3-phosphate dehydrogenase 6
N-acetyltransferase 6
elastase 5
tryptophan synthase 5
more...
Compound
DNA 13000
Dec 1363
Clin 564
phosphate 487
Mg2+ 446
calcium 426
ATP 399
pyrimidine 369
pyrimidine 368
oxygen 284
sodium 270
zinc 269
water 260
His 202
SDS 201
hydrogen 198
sulfate 182
manganese 182
salt 182
bromide 174
alanine 170
lysine 167
arginine 152
tryptophan 144
cysteine 130
EDTA 123
Asp 122
EDTA 121
methionine 116
tyrosine 109
leucine 108
DEAE 104
methyl methanesulfonate 104
glucose 87
H2O2 87
serine 86
MgCl2 78
ADP 78
ADP 77
ADP 77
ammonium 75
glycerol 73
threonine 69
nitrogen 68
iron 66
GTP 66
silver 63
adenosylmethionine 62
galactose 62
urea 62
Phe 61
copper 56
phenol 55
tryptophan 54
uridine 54
dUTP 51
NH2 51
tryptophan 50
acetate 50
tryptophan 50
NAD 47
ACS 46
ACS 46
cobalt 45
Tris 44
PEG 44
acrylamide 43
Gly 43
Tris 42
AMP 41
ethanol 41
dATP 40
Agarose 39
BLM 38
valine 38
HCl 38
nitric oxide 38
iodine 36
PAM 35
potassium 35
PAM 35
TEM 35
ADP-ribose 34
pyrene 33
aspartic acid 32
glutamic acid 31
aspartic acid 31
glutamate 31
A 1 31
dCTP 30
proline 30
NAD 30
aspartic acid 30
chloroform 30
glutamine 30
aspartic acid 30
cadmium 29
asparagine 29
nickel 29
Triton X-100 29
TTP 28
Adenine 28
aldehyde 28
formamide 27
aldehyde 27
MTT 27
Guo 25
40S 25
mercury 25
methane 25
MIC 24
caffeine 24
XPA 24
XPA 24
PEG 23
TNF 23
formaldehyde 23
Ile 22
COS 21
acridine 21
THF 21
DMS 20
CTP 20
Hemoglobin 20
CaCl2 19
hydroxide 19
formaldehyde 19
nitrate 19
C-3 18
Uracil 18
TOF 18
Deoxyribonucleic acid 18
3-aminobenzamide 18
PIN 18
ammonia 18
palmitic acid 18
retinoic acid 18
xylose 18
DMSO 18
cAMP 18
VP-16 17
Cyt 17
BAL 17
Histone 17
hydroxylamine 17
dCMP 17
deoxyribose-5-phosphate 17
Pac 17
PMA 17
CAM 17
hydroxylamine 17
nicotinamide 17
benzene 16
dGTP 16
guanidine 16
EMS 16
A 3 16
NTA 15
N-acetylcysteine 15
PAM 15
more...