Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.30.2 (
endonuclease
)
18,621
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We found a novel G-->A change at nucleotide -25 within the promoter of the CTSS gene encoding the elastase
cathepsin S
. The CTSS -25G/A polymorphism could be detected by digestion with
endonuclease
BfmI. The frequency of the CTSS -25A allele was 0.457 in Caucasians and 0.431 in Canadian Inuit. Because of the importance of the CTSS gene product in vascular matrix remodeling, this polymorphism may be useful in the study of associations with atherosclerosis and related phenotypes.
...
PMID:Human cathepsin S gene (CTSS) promoter -25G/A polymorphism. 1072 71
