Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.1.30.2 (endonuclease)
 18,621 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three groups of turkeys were inoculated with strains of C. psittaci (B577, VS1, TT3) from different restriction endonuclease groups. Turkeys were necropsied at 15 times through post-inoculation day 70. Birds infected with the TT3 strain were lethargic and had decreased body weight. After forced exercise, dyspnea was seen in VS1-infected turkeys. Pericarditis was the most severe lesion in TT3-infected birds. Airsacculitis and bronchopneumonia were the most severe lesions in VS1-infected turkeys. Lateral nasal adenitis was in both VS1- and TT3-infected birds. Only mild peribronchial pneumonia was in B577-infected turkeys. Chlamydial antigen, identified by light microscopy using an immunoperoxidase technique, was seen from post-inoculation days 9 through 50 in the lateral nasal gland and at earlier times in other tissue from VS1- and TT3-infected turkeys. No chlamydial antigen was detected in tissue from B577-infected birds. These studies showed that chlamydial strains from different restriction endonuclease groups are associated with distinct disease syndromes in turkeys.
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PMID:Respiratory and pericardial lesions in turkeys infected with avian or mammalian strains of Chlamydia psittaci. 268 47

The present study was designed to comparatively investigate 10 Rhodococcus equi isolates from cases of lymphadenitis in cattle. The isolates could be identified by cultural and biochemical properties. By serotyping the R. equi isolates 9 and 1, cultures could be classified as Nakazawa's serotypes 15 and 8, respectively. The isolates did not agglutinate rabbit erythrocytes, were uniformly susceptible to most of the antibiotics tested, did not contain plasmids nor expressed virulence-associated proteins and yielded identical patterns in protein fingerprinting. To further analyze the epidemiological relationships, the isolates were additionally subjected to DNA fingerprinting. This was performed by pulsed-field gel electrophoresis (PFGE) after digestion of the chromosomal DNA with the endonuclease AsnI. PFGE analysis of the chromosomal DNA revealed 4 DNA restriction groups with DNA pattern I with 7 isolates as predominant group and DNA pattern II to IV with one isolate, respectively. The present results indicate that a single R. equi clone belonging to Nakazawa's serotype 15 and according to PFGE to DNA restriction pattern I of the present investigation seems to be responsible for most of the cases of lymphadenitis of cattle described in this study.
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PMID:Identification and epidemiological relationship of Rhodococcus equi isolated from cases of lymphadenitis in cattle. 944 Jan 94