Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.30.2 (
endonuclease
)
18,621
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Using a DNA probe for the switch region of immunoglobulin heavy chain genes, together with the restriction
endonuclease
Sst I, we detected a particular polymorphic DNA pattern in 17 of 28 patients (60.7%) with
psoriatic arthropathy
but in only 5 of 41 patients (12.2%) with psoriasis alone. Our findings suggest that genes in the immunoglobulin region confer susceptibility to the development of arthropathy in patients with psoriasis.
...
PMID:Arthritis in patients with psoriasis is associated with an immunoglobulin gene polymorphism. 283 8
