Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.30.1 (
S1 nuclease
)
3,660
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
An
S1 nuclease
protection assay was designed to study the splicing pattern of the alternatively spliced beta A4 amyloid gene (
APP
gene) of Alzheimer's disease (AD). We determined the splicing pattern of the
APP
gene in fetal, adult, aged adult and AD human cortex. The results suggest that alternative splicing of the
APP
gene in AD is not significantly different from age-matched controls, but distinct from the developing fetal brain.
...
PMID:Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients. 185 28