Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.3.9 (glucose-6-phosphatase)
 3,081 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
glucose-6-phosphatase 3059
insulin 721
phosphoenolpyruvate carboxykinase 479
microsomal 421
endoplasmic reticulum 325
glucokinase 272
hexokinase 254
alkaline phosphatase 218
Sep 204
glucose-6-phosphate dehydrogenase 199
acid phosphatase 190
Mol 172
G6Pase 166
pyruvate kinase 138
glycogen phosphorylase 134
glucagon 131
fructose-1,6-bisphosphatase 127
lactate dehydrogenase 121
ATPase 121
GSD 117
phosphatase 111
5'-nucleotidase 111
glycogen synthase 98
adenosine triphosphatase 97
catalase 93
ATP 87
cytochrome P-450 83
albumin 80
Glucose-6-phosphatase 79
NADPH 79
pyruvate carboxylase 76
phosphofructokinase 69
glucose transporter 67
hemoglobin 67
superoxide dismutase 65
fatty acid synthase 65
glucose-6-phosphate transporter 62
gamma-glutamyl transpeptidase 61
AMP-activated protein kinase 60
aspartate aminotransferase 58
NADH 57
reductase 53
PEPCK 51
peroxisome proliferator-activated receptor 50
protein kinase B 50
insulin receptor 48
leptin 46
AMP 44
pyrophosphatase 43
IRS-1 42
membrane-bound 41
esterase 40
glutamate dehydrogenase 40
rhabdomyosarcoma 39
PGC 37
alanine aminotransferase 37
TAT 37
GSH 35
alpha-fetoprotein 34
cytochrome 33
malate dehydrogenase 32
cytochrome P450 32
glutathione peroxidase 30
gamma-glutamyltranspeptidase 29
glucocorticoid receptor 29
AKT 28
lipase 27
beta-glucuronidase 27
G6PC3 26
glycolytic enzyme 26
adenylate cyclase 26
acetyl-CoA carboxylase 25
NAD 25
STZ 24
adiponectin 24
glucose transporter 4 24
amylase 24
6-phosphogluconate dehydrogenase 24
isocitrate dehydrogenase 23
peroxisome proliferator-activated receptor gamma 22
more...
Disease
diabetes 383
hyperglycemia 205
glycogen storage disease 192
hypoglycemia 148
type 2 diabetes 148
hepatocellular carcinoma 143
GSD 117
GSD 117
cancer 114
GSD I 109
tumor 103
obesity 91
carcinogenesis 68
hyperinsulinemia 54
hyperlipidemia 53
glucose intolerance 52
neutropenia 47
fatty liver 37
GSH 36
hyperuricemia 31
metabolic disorder 31
cirrhosis 31
adenoma 22
lactic acidosis 22
metabolic syndrome 22
carcinoma 21
depression 19
liver cancer 17
type 1 diabetes 17
cold 17
dyslipidemia 15
hypertension 15
liver disease 15
malnutrition 14
tumorigenesis 14
HCC 14
hepatitis 13
renal disease 11
hypercholesterolemia 10
AIN 10
ischemia 9
Alzheimer's disease 8
Farber 8
inflammatory bowel disease 8
acute renal failure 8
uterus 8
enzyme deficiency 8
Glycogen storage disease type Ib 8
renal failure 8
neoplastic transformation 7
atherosclerosis 7
severe congenital neutropenia 7
sepsis 7
FAS 7
hyperphagia 7
gout 7
proteinuria 7
West 6
adenocarcinoma 6
sepsis 6
Schistosoma mansoni 6
SDS 6
hypothyroidism 6
alcoholic fatty liver 6
hepatitis B 6
cholestasis 6
hyperthyroidism 6
failure to thrive 6
Placenta 6
NOD 6
HCA 6
Hers 5
ketosis 5
Adenovirus 5
hepatic adenoma 5
epididymis 5
fits 5
malaria 5
lymphoma 5
pulmonary hypertension 5
more...
Symptom
hepatomegaly 57
starvation 38
anesthesia 6
diarrhea 5
polyuria 5
weakness 4
polydipsia 4
anorexia 4
splenomegaly 3
exhaustion 3
lethargy 3
hypothermia 3
seizures 2
Decreased activity 2
hypotonia 2
acute stress 2
acidity 2
cachexia 1
Ill 1
hunger 1
Cushingoid 1
constipation 1
collapse 1
bradypnea 1
respiratory distress 1
overweight 1
ataxia 1
Cushingoid 1
ketonuria 1
pain 1
hepatosplenomegaly 1
autodigestion 1
vomiting 1
menopausal symptoms 1
abdominal pain 1
emaciation 1
Drug
NADH 61
Glucagon 20
ascorbate 19
vitamin E 18
Fructose 17
lysine 13
lactose 9
Fraction 9
Ethanol 6
Glycerol 5
ROS 5
Leaf 5
Portal 5
Albumin 4
PCB 4
Vitamin E 4
Rosiglitazone 3
CaCl2 3
CaCl2 3
Glutathione 3
MRC 3
Growth hormone 3
Gel 3
CaCl2 3
Growth hormone 3
Nephron 3
EE2 2
IFN-gamma 2
NAG 2
Troglitazone 2
CTX 2
niacin 2
Vitamin B 2
EPA 2
citric acid 2
Pronase 2
CSF 2
G-CSF 2
1-Deoxynojirimycin 1
Hetrazan 1
Sodium nitroprusside 1
CrCl3 1
Kenyan 1
DNase I 1
Asparaginase 1
ADR 1
Liraglutide 1
Orphan 1
Nitazoxanide 1
Ringer's solution 1
Cellulase 1
ADM 1
Ranitidine 1
Itraconazole 1
Amiloride 1
Emodin 1
Pegaspargase 1
Adriamycin 1
Glycyrrhiza 1
Acacia 1
L-tyrosine 1
Dasatinib 1
balanced salt solution 1
Alanine 1
TAT 1
Pentostam 1
Monosodium glutamate 1
Fenbendazole 1
ABC 1
ISP 1
Ginseng 1
Corn oil 1
Galactose 1
Metrizamide 1
Honey 1
Mutagen 1
Adenosine triphosphate 1
Indomethacin 1
pyridoxal phosphate 1
Bezafibrate 1
more...
Enzyme
glucose-6-phosphatase 3081
phosphoenolpyruvate carboxykinase 507
phosphoenolpyruvate carboxykinase 485
phosphoenolpyruvate carboxykinase 482
glucokinase 272
hexokinase 255
ATPase 231
alkaline phosphatase 220
glucose-6-phosphate dehydrogenase 207
phosphorylase 199
acid phosphatase 191
succinate dehydrogenase 146
pyruvate kinase 142
lactate dehydrogenase 138
gamma-glutamyl transpeptidase 122
5'-nucleotidase 116
catalase 97
protein kinase 94
pyruvate carboxylase 81
CPR 80
alanine aminotransferase 76
AMP-activated protein kinase 76
phosphofructokinase 75
aspartate aminotransferase 73
superoxide dismutase 73
diaphorase 68
succinic dehydrogenase 52
aldolase 47
fructose 1,6-bisphosphatase 45
glutamate dehydrogenase 41
glutamate dehydrogenase 41
glutamate dehydrogenase 41
tyrosine aminotransferase 39
cytochrome oxidase 38
malate dehydrogenase 38
demethylase 36
adenylate cyclase 31
phosphoglucose isomerase 31
glutathione peroxidase 30
nucleotidase 28
lipase 28
acetylcholinesterase 27
peroxidase 27
acetyl-CoA carboxylase 26
AMPK 25
beta-glucuronidase 25
phosphoglucomutase 25
isocitrate dehydrogenase 25
isocitrate dehydrogenase 25
CPT 24
6-phosphogluconate dehydrogenase 24
6-phosphogluconate dehydrogenase 24
glyceraldehyde-3-phosphate dehydrogenase 24
glyceraldehyde-3-phosphate dehydrogenase 22
AMPK 21
glyceraldehyde-3-phosphate dehydrogenase 21
NADPH-diaphorase 21
glyceraldehyde-3-phosphate dehydrogenase 21
glyceraldehyde-3-phosphate dehydrogenase 21
sorbitol dehydrogenase 20
alpha-glucosidase 20
UDP-glucuronosyltransferase 20
glutathione S-transferase 18
mitogen-activated protein kinase 18
monoamine oxidase 18
collagenase 17
NQO1 17
phosphatidylinositol 3-kinase 16
arginase 16
GSK 16
RNase 15
trypsin 15
focal adhesion kinase 15
pyruvate dehydrogenase 15
phosphodiesterase 15
triphosphatase 15
diaphorase 15
ornithine transcarbamylase 14
cholinesterase 14
NADPH oxidase 13
more...
Compound
glucose 1434
phosphate 326
glucose-6-phosphate 216
Dec 199
DNA 144
water 120
sodium 115
Clin 114
galactose 101
ATP 87
NADPH 81
NADPH 79
urea 78
Insulin 76
calcium 73
glycerol 64
cAMP 63
NADH 61
Glycogen 58
CCl4 57
alloxan 53
oxygen 52
AMP 49
alanine 49
creatinine 42
hexose 39
ethanol 39
nitrogen 39
GSH 38
GSH 38
nicotinamide 36
hexose 35
hexose 35
hexose 35
pentose 34
pentose 34
STZ 34
pentose 34
pentose 34
NAD 32
CoA 32
iron 29
aniline 28
glutamate 26
arginine 26
NAD 25
leucine 25
tyrosine 25
acetate 24
serine 24
sulfate 24
Triton X-100 24
glutamine 22
EDTA 22
EDTA 22
TNF 21
zinc 21
Glucagon 20
carbamyl phosphate 20
NADP 19
hydrogen 19
potassium 19
methionine 18
Fructose 17
lysine 17
PPi 17
His 17
Mg2+ 17
ADP 17
cadmium 16
UDP 15
salt 15
ADP 15
ADP 15
pyrene 14
vanadium 14
uridine 14
GlcNAc 14
ammonia 13
ammonium 13
more...