Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.9 (
glucose-6-phosphatase
)
3,081
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
glucose-6-phosphatase
3059
insulin
721
phosphoenolpyruvate carboxykinase
479
microsomal
421
endoplasmic reticulum
325
glucokinase
272
hexokinase
254
alkaline phosphatase
218
Sep
204
glucose-6-phosphate dehydrogenase
199
acid phosphatase
190
Mol
172
G6Pase
166
pyruvate kinase
138
glycogen phosphorylase
134
glucagon
131
fructose-1,6-bisphosphatase
127
lactate dehydrogenase
121
ATPase
121
GSD
117
5'-nucleotidase
111
phosphatase
111
glycogen synthase
98
adenosine triphosphatase
97
catalase
93
ATP
87
cytochrome P-450
83
albumin
80
Glucose-6-phosphatase
79
NADPH
79
pyruvate carboxylase
76
phosphofructokinase
69
hemoglobin
67
glucose transporter
67
superoxide dismutase
65
fatty acid synthase
65
glucose-6-phosphate transporter
62
gamma-glutamyl transpeptidase
61
AMP-activated protein kinase
60
aspartate aminotransferase
58
more...
Disease
diabetes
383
hyperglycemia
205
glycogen storage disease
192
type 2 diabetes
148
hypoglycemia
148
hepatocellular carcinoma
143
GSD
117
GSD
117
cancer
114
GSD I
109
tumor
103
obesity
91
carcinogenesis
68
hyperinsulinemia
54
hyperlipidemia
53
glucose intolerance
52
neutropenia
47
fatty liver
37
GSH
36
hyperuricemia
31
metabolic disorder
31
cirrhosis
31
metabolic syndrome
22
lactic acidosis
22
adenoma
22
carcinoma
21
depression
19
type 1 diabetes
17
liver cancer
17
cold
17
dyslipidemia
15
hypertension
15
liver disease
15
HCC
14
tumorigenesis
14
malnutrition
14
hepatitis
13
renal disease
11
hypercholesterolemia
10
AIN
10
more...
Symptom
hepatomegaly
57
starvation
38
anesthesia
6
diarrhea
5
polyuria
5
weakness
4
polydipsia
4
anorexia
4
splenomegaly
3
exhaustion
3
lethargy
3
hypothermia
3
seizures
2
Decreased activity
2
hypotonia
2
acute stress
2
acidity
2
cachexia
1
Ill
1
hunger
1
Cushingoid
1
constipation
1
collapse
1
bradypnea
1
respiratory distress
1
overweight
1
ataxia
1
Cushingoid
1
ketonuria
1
pain
1
hepatosplenomegaly
1
autodigestion
1
vomiting
1
menopausal symptoms
1
abdominal pain
1
emaciation
1
Drug
NADH
61
Glucagon
20
ascorbate
19
vitamin E
18
Fructose
17
lysine
13
Fraction
9
lactose
9
Ethanol
6
Glycerol
5
Portal
5
ROS
5
Leaf
5
PCB
4
Vitamin E
4
Albumin
4
Rosiglitazone
3
CaCl2
3
Gel
3
Growth hormone
3
CaCl2
3
Growth hormone
3
Glutathione
3
MRC
3
CaCl2
3
Nephron
3
EE2
2
Vitamin B
2
CSF
2
NAG
2
CTX
2
IFN-gamma
2
Pronase
2
EPA
2
Troglitazone
2
citric acid
2
niacin
2
G-CSF
2
Dasatinib
1
Alanine
1
more...
Enzyme
glucose-6-phosphatase
3081
phosphoenolpyruvate carboxykinase
507
phosphoenolpyruvate carboxykinase
485
phosphoenolpyruvate carboxykinase
482
glucokinase
272
hexokinase
255
ATPase
231
alkaline phosphatase
220
glucose-6-phosphate dehydrogenase
207
phosphorylase
199
acid phosphatase
191
succinate dehydrogenase
146
pyruvate kinase
142
lactate dehydrogenase
138
gamma-glutamyl transpeptidase
122
5'-nucleotidase
116
catalase
97
protein kinase
94
pyruvate carboxylase
81
CPR
80
alanine aminotransferase
76
AMP-activated protein kinase
76
phosphofructokinase
75
aspartate aminotransferase
73
superoxide dismutase
73
diaphorase
68
succinic dehydrogenase
52
aldolase
47
fructose 1,6-bisphosphatase
45
glutamate dehydrogenase
41
glutamate dehydrogenase
41
glutamate dehydrogenase
41
tyrosine aminotransferase
39
cytochrome oxidase
38
malate dehydrogenase
38
demethylase
36
phosphoglucose isomerase
31
adenylate cyclase
31
glutathione peroxidase
30
lipase
28
more...
Compound
glucose
1434
phosphate
326
glucose-6-phosphate
216
Dec
199
DNA
144
water
120
sodium
115
Clin
114
galactose
101
ATP
87
NADPH
81
NADPH
79
urea
78
Insulin
76
calcium
73
glycerol
64
cAMP
63
NADH
61
Glycogen
58
CCl4
57
alloxan
53
oxygen
52
AMP
49
alanine
49
creatinine
42
nitrogen
39
hexose
39
ethanol
39
GSH
38
GSH
38
nicotinamide
36
hexose
35
hexose
35
hexose
35
pentose
34
pentose
34
STZ
34
pentose
34
pentose
34
CoA
32
more...