Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.9 (
glucose-6-phosphatase
)
3,081
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A novel class of N,N-
dibenzyl
-N'-benzylidenehydrazines as potent and competitive
glucose-6-phosphatase
catalytic site inhibitors are described. Optimisation of this series identified compounds with IC(50) values as low as 170 nM.
...
PMID:N,N-dibenzyl-N'-benzylidenehydrazines: potent competitive glucose-6-phosphatase catalytic enzyme inhibitors. 1151 61
