Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.9 (
glucose-6-phosphatase
)
3,081
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Antibodies raised against purified components of
glucose-6-phosphatase
were used to study the transmembrane orientation of the complex. Measurements of
glucose-6-phosphatase
activities and immunoblot analysis of sealed microsomes and detergent-solubilized microsomes after treatment with proteases suggested that most of the catalytic subunit resides within the lumen of the endoplasmic reticulum. In contrast, other components of
glucose-6-phosphatase
are accessible to the cytoplasm. Treatment of the partially purified
glucose-6-phosphatase
enzyme with
glycopeptide N-glycosidase
indicated that the catalytic subunit of the enzyme was a glycoprotein.
...
PMID:Transverse topology of glucose-6-phosphatase in rat hepatic endoplasmic reticulum. 185 Feb 36
