Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.3.8 (phytase)
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Human Gene/Protein
inositol polyphosphate-1-phosphatase 12.0
multiple inositol polyphosphate phosphatase 11.7
LRP3 11.6
zinc finger protein 165 11.4
nuclear pore protein 11.2
IP6K3 10.5
Myo-inositol monophosphatase 10.3
CALB1 10.2
parotid secretory protein 9.9
SMIT2 9.8
inositol hexakisphosphate kinase 1 9.8
50kD 9.6
HMIT 9.4
IP6K2 9.4
phosphomonoesterase 9.3
NC2 9.3
PKE 9.3
IPK1 9.3
SmF 9.2
ASP1 9.0
BPGM 9.0
UBR1 8.8
TBCC 8.7
AC40 8.7
PRIM1 8.7
PSMB1 8.7
IP6K1 8.6
AOX1 8.6
BPP 8.6
putative G protein-coupled receptor 8.5
Napsin-A 8.5
PRH 8.4
putative G-protein 8.4
inositol polyphosphate multikinase 8.4
Ins 8.4
REQ 8.3
inositol phosphatase 8.3
NRC 8.3
APPL1 8.2
ST13 8.2
TAGLN 8.1
ash 8.1
K74 8.0
Inositol monophosphatase 8.0
AO7 8.0
GE1 7.9
SLC5A1 7.9
SLC15A1 7.9
T3E 7.9
HARS 7.8
SLY1 7.8
NSP 7.8
PTCH2 7.8
POPX2 7.8
N-acetylneuraminate lyase 7.8
HSD2 7.8
bisphosphoglycerate mutase 7.7
G24 7.6
LN1 7.6
PHT1 7.6
alkaline phosphomonoesterase 7.5
GMD 7.5
PPB 7.4
PSM 7.4
CSE1L 7.4
SLC2A2 7.4
TNX 7.3
TPT 7.2
SPCA 7.2
TUB 7.1
mannanase 7.0
KH2 7.0
peptide transporter 1 7.0
Cav1.4 6.9
alternative protein 6.9
myo-inositol oxygenase 6.8
K80 6.8
HAP 6.8
PGP 6.8
acid phosphatase 6.8
Maltase 6.8
Diamine oxidase 6.7
claudin 3 6.7
TRPV6 6.7
DRP 6.6
PROC 6.6
RGS1 6.6
intestinal alkaline phosphatase 6.6
TR4 6.5
MGA 6.5
Calnexin 6.4
PFB 6.4
MN1 6.4
NDR 6.4
Acid phosphatase 6.3
UDPG 6.2
STF 6.2
C48 6.2
beta-mannosidase 6.2
MCP 6.2
PTC3 6.1
HBD-3 6.1
phosphoglycerate mutase 6.0
aminoacylase 6.0
EPHX1 6.0
FCE 6.0
MM2 6.0
MD-2 5.9
S11 5.9
ADF 5.9
amylase 5.9
NDF 5.9
protamine 1 5.9
DMR 5.9
NTG 5.9
TEF1 5.9
DMB 5.8
SSF 5.8
GPR 5.8
BC2 5.8
PEPT1 5.7
LPA1 5.7
alpha-galactosidase 5.7
Sta 5.7
XPO1 5.6
DEAD-box RNA helicase 5.6
intestinal mucin 5.6
ENL 5.6
proline-rich protein 5.5
P42 5.5
IP1 5.5
IPP 5.5
ADPase 5.5
GPX2 5.4
RS1 5.4
RIL 5.4
AMR 5.4
BD1 5.4
TSK 5.4
PROT 5.4
Protein tyrosine phosphatase 5.4
K17 5.3
MUC2 5.3
alpha-amylase 5.2
40 kDa) 5.2
dual-specificity phosphatase 5.2
LAL 5.2
MES 5.2
AOX 5.2
myosin regulatory light chain 5.2
SCP 5.1
GLUT2 5.1
prostatic acid phosphatase 5.1
phosphatase 5.1
I-1 5.1
HCN 5.0
arylalkylamine N-acetyltransferase 5.0
divalent metal transporter 1 5.0
IGF I 5.0
CC1 5.0
more...
Disease
MHAC 12.0
Zar 9.7
hypophosphaturia 9.6
Johanson-Blizzard syndrome 9.4
BPP 8.8
Jacobsen syndrome 8.4
OA2 8.2
ash 8.0
dyschondroplasia 8.0
Shaver 7.6
MG infection 7.5
PPB 7.1
mineral deficiency 6.8
Hodgson 6.5
PIC 6.5
coprophagy 6.4
CHH 5.6
rickets 5.2
coccidiosis 5.2
SCP 5.1
MPE 5.1
SM1 5.0
SLS 5.0
Yersinia 5.0
protein deficiency 4.9
SLS 4.9
Stomach 4.6
Stomach 4.6
Stomach 4.6
EPS 4.6
enteritis 4.5
Stomach 4.5
PCS 4.5
EPS 4.4
OHD 4.4
PDR 4.4
Weaver 4.3
FMD 4.3
AAS 4.3
Lymph nodes 4.3
hypercalciuria 4.3
SDS 4.1
ACP 4.0
PTP 4.0
SSM 4.0
Brown 3.9
sporotrichosis 3.9
Shigella dysenteriae 3.9
fungemia 3.8
PER 3.8
pH increased 3.8
Meckel's diverticulum 3.7
TCP 3.7
LTD 3.7
iron deficiency anemia 3.7
RCM 3.6
Meckel's diverticulum 3.6
iron deficiency 3.5
FMD 3.5
Klebsiella 3.4
MRS 3.3
AIN 3.3
Tag 3.3
SAD 3.3
AGA 3.1
hypersensitivity pneumonitis 3.1
papillary thyroid cancer 3.0
Shigella 2.9
proliferative diabetic retinopathy 2.8
PCA 2.8
CCD 2.7
Mycoplasma 2.7
pseudotuberculosis 2.7
ICP 2.7
idiopathic dilated cardiomyopathy 2.7
CCD 2.7
PAA 2.6
hypercalcemia 2.6
Proteus 2.5
Shigella flexneri 2.4
PLS 2.4
PDB 2.2
lichen 2.2
lymphocytosis 2.2
malnutrition 2.1
agranulocytosis 2.0
sudden infant death syndrome 2.0
candidiasis 2.0
enteropathy 1.9
mole 1.8
glioblastoma multiforme 1.8
Newcastle disease 1.7
dyspepsia 1.7
Shiga 1.6
mole 1.6
myopathy 1.4
Bordetella 1.4
basal cell carcinoma 1.2
malabsorption 1.1
bone disease 1.1
Echinococcus 0.9
DBA 0.6
cleft palate 0.6
NHS 0.6
gastroesophageal reflux disease 0.4
SEM 0.4
ATM 0.3
Poland 0.3
dermatitis 0.2
STD 0.2
cold 0.1
Haemophilus 0.1
endocarditis 0.0
anemia -0.1
Best -0.2
chronic disease -0.2
cholera -0.4
TEM -0.4
TEM -0.5
inflammatory bowel disease -0.5
dehydration -0.6
cystic fibrosis -0.7
infertility -0.7
Mycobacterium -0.7
colorectal cancer -0.7
MCF -0.8
cytomegalovirus -0.8
tumorigenesis -0.8
colon cancer -0.9
fits -1.0
carcinogenesis -1.0
depression -1.1
GSH -1.3
Infection -1.3
osteoporosis -1.3
infectious diseases -1.4
malaria -1.5
renal disease -1.5
plaque -1.8
tumor growth -1.9
hepatocellular carcinoma -2.2
carcinoma -2.3
tuberculosis -2.3
atherosclerosis -2.3
breast cancer -2.3
HIV -2.4
Alzheimer's disease -2.8
AIDS -2.9
obesity -3.0
hypertension -3.4
cancer -4.1
diabetes -4.1
tumor -5.4
Symptom
skin irritant 8.0
No adverse effect 5.6
blackout 5.1
abnormal gait 3.8
Wind 3.6
starvation 3.3
acidity 2.4
tremor 2.1
shortness of breath 1.6
agitation 1.4
thinning 0.5
stigma 0.3
anorexia 0.2
collapse 0.2
diarrhea -0.3
cough -0.6
dyspnea -0.8
abdominal pain -1.0
pain -4.0
Drug
Pancreatin 9.2
RPH 8.2
Aluminum chloride 8.2
Carbadox 8.0
Sesame oil 7.9
Carbadox 7.8
Calan 7.7
Sodium citrate 7.1
Sodium citrate 7.1
dibasic calcium phosphate 7.0
Malachite Green 6.5
Calcium chloride 6.1
Isoptin 5.9
DMI 5.7
Bifidobacterium 5.6
RSM 5.5
SMP 5.4
Cellulase 5.0
citric acid 4.9
Irinotecan 4.3
PTC 4.2
APD 4.1
TTC 4.1
Galactose 3.9
NAG 3.9
DMAP 3.8
FeCl3 3.5
TiO2 3.5
Glycyrrhiza 3.5
ZnO 3.4
MgSO4 3.4
CaCl2 3.3
Amiloride 3.1
lysine 3.1
Itraconazole 3.0
-deoxyadenosine 2.9
CaCl2 2.9
CaCl2 2.9
Capsicum 2.8
NH3 2.8
L-tyrosine 2.7
Fraction 2.6
lactose 2.5
Gel 2.4
HCH 2.2
niacin 2.1
DNase I 1.9
nitroglycerin 1.8
Leaf 1.6
FAD 1.5
Asn 1.4
ascorbate 1.1
ampicillin 0.9
Biopolymers 0.9
IL-2 0.7
Ethanol 0.7
vitamin E -0.1
Enzyme
phytase 14.0
phytase 14.0
glucose-1-phosphatase 11.2
MIPP 10.9
phosphonatase 9.1
inositol polyphosphate kinase 8.5
tannase 8.5
xylanase 8.5
xylanase 8.4
RPH 8.3
oxalate decarboxylase 8.2
fructose-6-phosphate phosphoketolase 8.1
nicotianamine synthase 8.1
PepX 8.0
bile salt hydrolase 8.0
myo-inositol oxygenase 7.7
alcohol oxidase 7.2
inositol phosphatase 7.2
hydroxynitrile lyase 7.0
myo-inositol-1-phosphate synthase 6.9
acid phosphatase 6.9
threonine dehydrogenase 6.9
hydroxynitrile lyase 6.9
galactanase 6.9
hydroxynitrile lyase 6.7
mannanase 6.7
pectinase 6.6
inulinase 6.6
inulinase 6.5
pepsin 6.5
glucoamylase 6.4
phosphoglyceromutase 6.4
nitrilase 6.3
cellulase 6.3
chloroperoxidase 6.3
feruloyl esterase 6.2
CO dehydrogenase 6.1
oxalate oxidase 6.1
NCP 6.0
proteinase A 5.9
pyruvate oxidase 5.9
pyruvate oxidase 5.9
sortase A 5.7
p-nitrophenylphosphatase 5.7
isocitrate lyase 5.6
nucleotide pyrophosphatase 5.4
alginate lyase 5.4
beta-xylosidase 5.3
3'-exonuclease 5.3
aminopeptidase A 5.2
alpha-galactosidase 5.2
alpha-amylase 5.2
sucrase-isomaltase 5.2
beta-amylase 5.2
SCP 5.1
Pla 5.1
NPL 5.1
deaminase 5.1
chymosin 5.1
beta-glucosidase 5.1
glucose dehydrogenase 5.0
malate synthase 4.9
arginine decarboxylase 4.9
chitinase 4.9
beta-glucosidase 4.9
invertase 4.9
ADPase 4.9
alkaline phosphatase 4.8
lipase 4.7
sucrase 4.7
HDR 4.7
arginine decarboxylase 4.7
SMP 4.5
fatty acid desaturase 4.5
PGM 4.5
transhydrogenase 4.5
pullulanase 4.4
cytosine deaminase 4.4
triphosphatase 4.4
alpha-glucosidase 4.2
beta-secretase 4.2
lignin peroxidase 4.1
acylase 4.1
glyceraldehyde-3-phosphate dehydrogenase 4.1
carboxypeptidase A 4.0
PTPase 4.0
sulfatase 3.9
trypsin 3.9
glyceraldehyde-3-phosphate dehydrogenase 3.8
CD13 3.7
arylsulfatase 3.7
PCE 3.6
cellobiohydrolase 3.6
purine nucleoside phosphorylase 3.5
glyceraldehyde-3-phosphate dehydrogenase 3.5
glyceraldehyde-3-phosphate dehydrogenase 3.4
TOR 3.4
apyrase 3.4
laccase 3.4
leucine aminopeptidase 3.3
PTA 3.2
phosphoglucose isomerase 3.2
glucose oxidase 3.1
nitrogenase 3.1
endoglycosidase H 3.1
nitrite reductase 3.1
nitrite reductase 3.1
nitrite reductase 3.1
hormone-sensitive lipase 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.9
phosphoglycerate kinase 2.9
chymotrypsin 2.9
papain 2.9
PAH 2.9
histidine kinase 2.7
urease 2.7
urease 2.7
SPC 2.6
MDP 2.6
sialidase 2.6
asparaginase 2.6
tyrosinase 2.4
lysozyme 2.4
isocitrate dehydrogenase 2.4
phosphodiesterase 2.4
ricin 2.3
isocitrate dehydrogenase 2.2
aldolase 2.2
HSD 2.2
proteasome 2.1
beta-galactosidase 2.1
nitrate reductase 2.1
nitrate reductase 2.1
nitrate reductase 2.1
nitrate reductase 2.1
nitrate reductase 2.1
phospholipase D 2.1
phosphofructokinase 2.1
nitrate reductase 2.0
catalase 2.0
glutamate dehydrogenase 1.9
glutamate dehydrogenase 1.9
glutamate dehydrogenase 1.8
elastase 1.8
phospholipase C 1.8
alcohol dehydrogenase 1.8
ceruloplasmin 1.7
ATPase 1.5
phosphorylase 1.5
AST 1.4
ACE 1.4
caspase-1 1.3
alanine aminotransferase 1.3
lipoprotein lipase 1.2
aspartate aminotransferase 1.1
superoxide dismutase 1.1
MAP 1.1
carbonic anhydrase 1.1
DNase 1.1
beta-glucuronidase 1.1
more...
Compound
Glycerol-2-phosphate 13.0
Phytic acid 11.9
Monocalcium phosphate 10.1
D-ribose-1-phosphate 9.6
Nitrophenylphosphate 9.6
AME 9.3
C6H12O6 9.3
trimethylsilanol 8.8
dITP 8.0
epi-inositol 7.7
TME 7.7
25-hydroxycholecalciferol 7.7
phosphorus 7.7
NPP 7.3
Inositol phosphate 7.2
Inositol 7.1
dihydrogen phosphate 6.8
HAP 6.8
dihydrogen phosphate 6.8
tetraphosphate 6.7
Raffinose 6.7
Palmitoleic acid 6.7
1,2-cyclohexanedione 6.5
Titanium dioxide 6.4
MGA 6.3
D-gluconate 6.3
25-dihydroxycholecalciferol 6.1
Ins(1,4,5)P3 6.0
IAA 6.0
MPE 6.0
Alum 5.9
HfO2 5.8
DMB 5.8
MCP 5.8
IAA 5.8
PCMB 5.8
PCMB 5.8
PCMB 5.8
Lactic acid 5.7
PCMB 5.7
DMI 5.7
DMI 5.7
DMB 5.5
PMSF 5.5
ANI 5.5
phosphate 5.4
Kanamycin 5.2
MES 5.2
phosphoric acid 5.2
MES 5.2
Vitamin D3 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-nitrophenyl 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
Mannose 5.2
Malachite Green 5.1
Pectin 5.1
BDS 5.0
Starch 5.0
Arsenate 4.9
Malate 4.8
DCP 4.7
butanal 4.7
Flavonoid 4.7
2,3-diphosphoglycerate 4.6
GAP 4.5
glucose-6-phosphate 4.5
Tunicamycin 4.5
succinic acid 4.4
succinic acid 4.4
succinic acid 4.4
succinic acid 4.4
PTS 4.4
Inulin 4.4
Lactate 4.4
Tween 80 4.4
MIA 4.4
TPD 4.4
malic acid 4.4
2,3-butanediol 4.3
2,3-butanediol 4.3
2,3-butanediol 4.3
GA3 4.3
Vitamin D3 4.3
Trypsin 4.3
isobutyric acid 4.3
IPA 4.3
zinc 4.3
IPA 4.3
IPA 4.2
Ether 4.2
NTA 4.2
IPA 4.2
Ether 4.2
ITC 4.2
Casein 4.2
DEAE 4.2
EDTA 4.2
EDTA 4.2
SDS 4.2
BAA 4.1
2-butanone 4.1
DCM 4.1
malic acid 4.1
malic acid 4.1
DCP 4.1
Bordeaux 4.1
SAD 4.1
malic acid 4.0
TDP 4.0
SSM 4.0
T 1 4.0
His 3.9
Galactose 3.9
Phenylalanine 3.9
CdCl2 3.9
Hydroxyproline 3.8
oxalic acid 3.8
succinic acid 3.8
Ile 3.8
Gly 3.8
Coenzyme Q10 3.7
p-xylene 3.7
PPO 3.7
TCP 3.7
TCP 3.7
LTD 3.7
XTT 3.7
A 3 3.6
TCP 3.6
TCP 3.6
PCE 3.6
isopentenyl diphosphate 3.6
GGG 3.6
threonine 3.6
Lignin 3.6
lysine 3.6
MCH 3.5
methionine 3.5
oxalic acid 3.5
oxalic acid 3.5
Chlorophyll 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
oxalic acid 3.5
more...