Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.8 (
phytase
)
1,997
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The activity and basic kinetic constants of
phytase
were studied in chicken erythrocytes during animal development. The regulatory inhibition of
phytase
by IHP and
2,3-BPG
takes place at key stages of the development. As in mammals, there is a specific control of the levels of organic phosphate involved in the oxygenation process of haemoglobin, during animal development.
...
PMID:Phytase activity in chicken erythrocytes and its control by organic phosphates (glycerate-2,3-P2 and inositol-P5) during avian development. 298 56
In mammals, bisphosphoglycerate-synthase activity, whose assay methods are previously discussed, increases gradually along erythropoiesis, leading to a consequent enhancement of 2,3-bisphosphoglycerate formation. Avian erythrocytes, on the other hand, contain inositol-pentaphosphate as major organic phosphate starting from egg eclosion, which substitutes embrionary ATP and
2,3-BPG
in the regulatory function. The IHP of
phytase
and the disappearance of
2,3-BPG
synthesis, also inhibitor of enzyme activity, should be considered responsible for IPP accumulation.
...
PMID:[Metabolism of the organic phosphate regulators of oxygenation in cells of the erythrocyte series in birds and mammals]. 629 20
