Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.8 (
phytase
)
1,997
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Feeding pharmacological zinc (Zn) to weaned pigs improves growth, and dietary
phytase
improves P and Zn availability.
Metallothionein
(MT) increases in the duodenum, kidney, and liver of pigs fed 1000 mg Zn/kg with
phytase
or 2000 mg Zn/kg with or without
phytase
when fed for 14 d postweaning. The goal of this study was to determine the effects of feeding pharmacological Zn and
phytase
on tissue minerals, MT, mineral excretion, and apparent retention. Twenty-four newly weaned pigs (20 d; 7.2 kg) were individually fed twice daily, a basal diet supplemented with 0, 1000, or 4000 mg Zn/kg as Zn oxide, without or with
phytase
(500
phytase
units [FTU]/kg) for 14 d, followed by a basal diet (100 mg Zn/kg) without
phytase
for 7 d. Pigs fed 4000 mg Zn/kg without
phytase
had higher (p=0.01) plasma, hepatic, renal Zn, renal Cu, and hepatic, renal, and jejunal MT than pigs fed the basal diet or 1000 mg Zn/kg. Duodenal MT was higher (p=0.0001) in pigs fed 1000 and 4000 mg Zn/kg than in pigs fed the basal diet. In pigs fed 1000 and 4000 mg Zn/kg, Zn loading occurred during the first 11 d of supplementation; by d 14, excess Zn was being excreted in the feces.
...
PMID:Dietary pharmacological or excess zinc and phytase effects on tissue mineral concentrations, metallothionein, and apparent mineral retention in the newly weaned pig. 1603 57
