Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.1.3.5 (5'-nucleotidase)
 3,167 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Venoms of Heloderma horridum and Heloderma suspectum were analyzed for the possible presence of purine and pyrimidine nucleosides. Adenosine, cytidine, guanosine, hypoxanthine, inosine, and uridine were found in mug quantities. These amounts are much smaller than those seen in many elapid or viperine venoms, but greater and more varied than those found in crotaline venoms. While their contribution to the hypotension induced by Heloderma venoms may be minor, venom nucleosides nonetheless act in concert with kallikreins/hemorrhagins, alkaline phosphomonoesterase, 5'-nucleotidase, helodermin, helospectins, helothermine, and serotonin. The use of nucleosides as toxins is therefore a generalized squamate strategy, rather than the exclusive province of snakes. Both Heloderma venoms were found to be devoid of NADase and phosphodiesterase activities. Enzymes to release endogenous purines in the prey, are not significant components of Heloderma venoms.
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PMID:Nucleoside composition of Heloderma venoms. 1843 May 99

In a study with the light microscope, we investigated the tissular localization of glycogen, R.N.A., and 4 phosphohydrolases in the pelvic fin bud of two species of Trout,Salmo fario andSalmo gairdneri, Pisces, Teleostei. In both, the epiderm bud, including the "pseudo-apical cap", is devoid of glycogen and the amount of R.N.A. histochemically demonstrable is not greater than in epidermal regions outside the bud. InSalmo gairdneri but not inSalmo fario, we observed four phosphatases, only in the inner layer of the epiderm of the fin bud: alkaline phosphomonoesterases, naphthol AS-BI acid phosphatase, nonspecific ATPase and AMPase. The "initial mesenchyme", from the somatopleura's proliferation, contains a great quantity of R.N.A. In both species we found there the four enzymes. The "secondary mesenchyme", obtained from the dispersion of four ventral somitic processes, has a metabolism that is similar inSalmo fario andSalmo gairdneri; alkaline phosphomonoesterase is found only inSalmo gairdneri.
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PMID:[The first stades of genesis of the pelvic fin anlage in the Trout (Salmo fario andSalmo gairdneri) : II. Comparative histochemical data]. 2830 45


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