Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.5 (
5'-nucleotidase
)
3,167
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Highly sensitive techniques have been used for the assay of a range of marker enzymes including lactase, sucrase, alkaline phosphatase, leucyl-beta-naphthylamidase (brush border), and
5'-nucleotidase
(basolateral membrane) in jejunal biopsy homogenates from patients with adult coeliac disease with and without
steatorrhoea
and from a control group. The absorption of D-xylose and vitamin B12 was compared in the two groups with coeliac disease. All enzymes assayed were equally depressed in both groups of coeliac disease as compared with the controls. The absorption of D-xylose and vitamin B12 were reduced in the patients with
steatorrhoea
compared with those without
steatorrhoea
. The findings suggest that lack of
steatorrhoea
in some patients with coeliac disease is due to better preservation of the ileal function rather than to a less severe jejunal mucosal injury.
...
PMID:Enzyme activities in jejunal biopsy samples from patients with adult coeliac disease with and without steatorrhoea. 632 31
