Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.5 (
5'-nucleotidase
)
3,167
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effect on protein localisation of a carboxy-terminal deletion of periplasmic UDP-glucose hydrolase (
5'-nucleotidase
) has been determined in vivo using immunoprecipitation. The
processed form
of the truncated protein was found in the periplasm; however, in contrast to the situation with the normal protein, the preprotein form of the truncated protein was also found in the periplasm. This result confirms previous semi-in vitro data and supports the suggestion that a conformational change in a membrane-bound intermediate is a normal part of the secretory pathway.
...
PMID:Altered localisation of the precursor of a secreted protein in E. coli by a carboxyl-deletion. 283 84
