Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.3.16 (calcineurin)
 17,112 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
ELP95 10.9
small nuclear ribonucleoprotein polypeptide B 10.9
synaptotagmin-like 2 10.9
N-acetyltransferase 6 10.9
PPP1R11 protein 10.9
Histone H2A type 1-J 10.9
line-1 reverse transcriptase 10.9
transcription factor CP2-like 3 10.9
FLJ23654 10.9
BTF3L4 10.9
protein kinase, cAMP-dependent, regulatory, type II, alpha 10.9
Acetylcholinesterase-associated collagen 10.9
solute carrier family 39 (zinc transporter), member 10 10.9
TMEM225 10.9
Phosphodiesterase 7A 10.9
Alpha-tropomyosin 10.9
vaccinia related kinase 1 10.9
protein phosphatase-1 10.9
A-kinase anchoring protein 18 10.9
OK/SW-CL.16 10.9
Calcineurin catalytic subunit 10.9
ARP mRNA 10.9
FLJ20311 10.9
myotubularin-related protein 1 10.9
membrane metallo-endopeptidase-like 1 10.9
IQWD1 10.9
zinc finger with KRAB and SCAN domains 3 10.9
DIS3 protein 10.9
PPP1R6 10.9
Lst-1 10.9
caspase 9 splice variant 10.9
PAX interacting protein 1 10.9
PPP1R3E 10.9
translocon-associated protein gamma 10.9
HD domain containing 2 10.9
insulin-stimulated protein kinase 1 10.9
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 10.9
Tyrosine-protein kinase 10.9
per1-like domain containing 1 10.9
transmembrane protein 40 10.9
protein phosphatase type 2A catalytic subunit 10.9
protein phosphatase 10.9
SYT16 10.9
Down syndrome critical region gene 1-like 2 10.9
CALNB 10.9
3-oxoacid CoA transferase 2 10.9
PP2A-beta 10.9
calcineurin 10.8
calcineurin A beta 10.7
scapinin 10.6
protein phosphatase methylesterase 1 10.5
leucine carboxyl methyltransferase 10.5
PPP1R8 10.5
LCMT1 10.5
LCMT 10.5
PP-1G 10.5
PPP1R3G 10.4
Regulator of calcineurin 3 10.4
sds22 10.4
PR55 beta 10.4
PPP1R5 10.4
PPP1R2 10.4
protein phosphatase 2B 10.3
Down syndrome candidate region 1 10.3
NIPP1 10.3
PPTC7 10.3
PPP3R2 10.3
PP2C gamma 10.3
GBPI-1 10.3
Myo16b 10.3
PPP3CB 10.2
PR72 10.2
RCAN3 10.2
ZAKI-4 10.2
CNA1 10.1
DSCR1L2 10.1
PPP1R3 10.1
protein phosphatase 3 10.1
CAIN 10.1
RCAN2 10.1
more...
Disease
Normal anion gap metabolic acidosis 10.9
HMN1 10.9
Deficiency of protein phosphatase 10.9
Kaposi's sarcoma, lung 10.9
Autoimmune skin disease 10.9
Renal tubulitis 10.9
CNA1 10.1
CNA2 10.0
Facial psoriasis 9.9
Azotemic osteodystrophy 9.9
Circinate balanitis 9.9
DSCR 9.9
Facial seborrheic dermatitis 9.9
Advanced Sleep Phase Syndrome 9.3
Plasma cell balanitis 9.1
FBH3 8.9
NEM1 8.3
APBD 8.3
Atopic keratoconjunctivitis 8.2
Erosive pustular dermatosis 8.1
HHT3 8.1
precancerous dermatosis 8.1
Actinic reticuloid 8.1
Granuloma gluteale infantum 8.1
Renal magnesium wasting 8.1
Drug-induced hyperkalemia 7.9
Inverse psoriasis 7.8
Scalp psoriasis 7.6
Plasma cell cheilitis 7.5
Idiopathic guttate hypomelanosis 7.5
Chronic hyperkalemia 7.5
FWT2 7.5
Exfoliative cheilitis 7.5
Frontal fibrosing alopecia 7.5
KCS2 7.4
oculocerebrofacial syndrome 7.4
streptoccocal 7.3
EPM2B 7.1
Cutaneous lupus erythematosus 7.1
Chronic paronychia 7.1
Acute renal insufficiency 7.1
Increased drug resistance 7.1
Vitritis 7.1
Autoimmune myocarditis 7.0
Segmental vitiligo 6.8
Prurigo nodularis 6.8
Zoon's balanitis 6.6
PanIN-1B 6.6
Cholestatic hepatitis 6.5
RP23 6.5
Critical illness myopathy 6.5
PPR2 6.4
Erosive pustular dermatosis of the scalp 6.3
BK virus nephropathy 6.3
Opitz 6.2
viral leukemogenesis 6.2
Chronic actinic dermatitis 6.2
Akinetic mutism 6.2
ASM 6.0
Gingival hyperplasia 6.0
PPP 5.9
Myometrium 5.9
Ruvalcaba syndrome 5.9
refractory CML 5.9
pityriasis alba 5.8
Acrodermatitis continua of Hallopeau 5.8
Lichen striatus 5.8
Reversible posterior leukoencephalopathy syndrome 5.8
Canarypox 5.8
Dandruff 5.7
Focal segmental glomerulosclerosis 5.7
OSX 5.7
Hand eczema 5.7
NINA 5.6
BSND 5.6
balanitis 5.6
LBD 5.5
SCA12 5.5
EVR 5.5
LTD 5.5
more...
Symptom
KIDNEY 6.9
rundown 6.2
skin pain 4.6
Vulvodynia 4.4
trigeminy 4.3
phosphatemia 4.1
disturbed balance 4.0
dry skin 3.5
scaly skin 3.4
starvation 3.0
Anoxia 2.8
Burning 2.6
No adverse effect 2.5
CSR 2.4
intention tremor 2.4
bladder pain 2.3
memory loss 2.2
erythema 2.2
loss of balance 2.0
Spots 2.0
oliguria 2.0
dysesthesia 2.0
tenesmus 2.0
Catch 1.9
dry eye 1.8
Decreased activity 1.8
catatonia 1.7
Gastrointestinal symptoms 1.7
Fluctuation 1.6
polyuria 1.6
bone pain 1.6
leg edema 1.5
forgetfulness 1.5
myoclonus 1.4
skin irritation 1.4
tense 1.4
functional recovery 1.2
renal colic 1.2
rigors 1.2
consciousness disturbance 1.2
livedo 1.1
neuralgia 1.1
arthralgia 1.1
muscle cramps 1.0
neurological disability 1.0
seizures 1.0
orofacial pain 1.0
Stiffness 0.9
otalgia 0.9
leg pain 0.9
twitching 0.9
blurred vision 0.8
chorea 0.8
microbial colonization 0.8
collapse 0.8
tremor 0.8
abnormal gait 0.7
exhaustion 0.7
acute stress 0.7
ataxia 0.6
dysuria 0.6
tingling 0.5
acute pain 0.5
Sedation 0.5
Neuropathic pain 0.4
lethargy 0.4
anosmia 0.3
diarrhea 0.3
photophobia 0.2
paresthesia 0.2
nausea 0.2
hyperoxia 0.1
cerebellar ataxia 0.0
cachexia -0.0
dysarthria -0.0
fatigue -0.0
hypotonia -0.1
acute abdominal pain -0.1
constipation -0.1
heartburn -0.2
more...
Drug
Pimecrolimus 9.0
Belatacept 9.0
Rapamune 8.4
Fingolimod hydrochloride 8.2
Tacrolimus 7.6
Prograf 7.5
Basiliximab 7.3
Basiliximab 7.3
Cellcept 6.9
Cellcept 6.9
Olvanil 6.7
K-252a 6.5
Neoral 6.5
Everolimus 6.3
Tepoxalin 6.2
Daclizumab 6.1
Maduramicin 6.1
Coal tar 5.9
Tryptophane 5.9
Trifluoperazine 5.7
Efalizumab 5.6
Alefacept 5.6
Efalizumab 5.6
Stelazine 5.5
MT6 5.5
Olomoucine 5.4
Campath 5.3
Campath 5.3
Epoetin beta 5.2
Bethanidine 5.2
Sinefungin 5.1
Aluminum chloride 5.1
Ibudilast 5.0
Antithymocyte globulin 4.9
Radicicol 4.8
Mycophenolic acid 4.8
Caspofungin 4.7
Tolfenamic acid 4.5
Rasburicase 4.4
Etravirine 4.4
Valganciclovir 4.4
Pegasys 4.3
SMP 4.3
Imuran 4.2
Diamminedichloroplatinum 4.2
Perphenazine 4.1
CMX 4.1
Forskolin 4.0
Red ginseng 4.0
Poudre 4.0
Fluphenazine 3.9
Protamine sulfate 3.9
Retinoic Acid 3.9
Anidulafungin 3.9
Parkin 3.8
Parkin 3.8
Hyperforin 3.8
Saha 3.8
Vandetanib 3.8
DPE 3.8
Rolipram 3.7
Rituximab 3.7
IPD 3.6
Clobetasol propionate 3.6
Dithranol 3.6
Budesonide 3.6
ISP 3.6
IL-2 3.5
TAC 3.5
Calcipotriol 3.5
ZnCl2 3.5
ZnCl2 3.5
AC2 3.4
Artesunate 3.4
Fulvestrant 3.4
Navelbine 3.4
Fenoldopam 3.3
Angiotensin II 3.3
Carbenoxolone 3.3
Casodex 3.3
more...
Enzyme
calcineurin 10.9
EC 1.3.1.16 10.9
SMP-I 10.0
protein phosphatase 2A 9.9
reductase phosphatase 9.7
type 1 protein phosphatase 9.4
glycogen synthase phosphatase 9.0
phosphopantothenoylcysteine decarboxylase 8.7
aspartate beta-hydroxylase 8.5
SuyAB 8.3
phosphorylase kinase 8.0
BCKDH 7.9
glucosamine kinase 7.9
citryl-CoA lyase 7.4
carboxypeptidase 1 7.3
pyruvate dehydrogenase phosphatase 7.2
CaMKII 7.0
yapsin 1 7.0
phosphorylase 6.9
phosphatidate phosphatase 6.7
inositol polyphosphate 4-phosphatase 6.7
K+-transporting ATPase 6.6
phosphoserine phosphatase 6.4
EC 2.6.1.16 6.4
peptidyl-prolyl cis-trans isomerase 6.3
ceramide synthetase 6.2
PTPase 6.2
chymotrypsin C 6.2
separase 6.2
PLP phosphatase 6.1
AMP-activated kinase 6.1
DNA 3'-phosphatase 6.1
phosphoinositide 5-phosphatase 6.0
myosin light chain kinase 6.0
p-nitrophenylphosphatase 5.9
phosphatidylinositol phospholipase C 5.8
TOR 5.8
protein kinase 5.8
AMPK 5.7
12-oxophytodienoate reductase 5.7
phosphoglucosamine mutase 5.7
quinate dehydrogenase 5.7
PAF acetyltransferase 5.6
acetylornithine aminotransferase 5.5
quinate dehydrogenase 5.5
GSK 5.5
PPH 5.5
PAF acetyltransferase 5.5
caffeoyl-CoA O-methyltransferase 5.5
NAD+ kinase 5.5
2',3'-cyclic nucleotide phosphohydrolase 5.5
PKG 5.4
polo-like kinase 1 5.4
lysine-ketoglutarate reductase 5.4
inositol polyphosphate kinase 5.4
chitin synthase 5.3
protein N-myristoyltransferase 5.3
STK2 5.3
CTD kinase 5.3
neutral sphingomyelinase 5.3
EC 2.4.1.11 5.3
branched-chain alpha-keto acid dehydrogenase 5.3
dihydroneopterin aldolase 5.2
protein kinase C 5.2
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.2
IMP dehydrogenase 5.1
beta-glycerophosphatase 5.1
6-phosphofructo-2-kinase 5.1
cellulose synthase 5.0
diacetyl reductase 5.0
eEF2 kinase 5.0
calcium pump 5.0
protein methylase II 4.9
nucleoside triphosphate phosphohydrolase 4.9
MEKK1 4.8
thiopurine methyltransferase 4.8
10-formyltetrahydrofolate dehydrogenase 4.8
acetyl-CoA carboxylase 4.7
cytochrome b6/f complex 4.7
cdc2 4.7
more...
Compound
2-(2,5-dimethoxyphenyl)acetamide 10.9
S 46 10.9
Agrimophol 10.9
Acanthifolicin 10.9
N-(4-oxo-1(4H)-naphthalenylidene)benzenesulfonamide 10.9
Tautomycin 10.0
C10H13NO2 9.9
Chaulmoogric acid 9.9
Fostriecin 9.7
C8H8O5 9.5
C8H8O5 9.5
C8H8O5 9.5
C8H8O5 9.5
C8H8O5 9.5
C8H8O5 9.5
C8H8O5 9.5
Calyculin A 9.5
Okadaic acid 9.4
C8H8O5 9.3
7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid 9.3
bicyclo[2.2.1]heptane-2-carboxylic acid 9.3
C8H8O5 9.3
bicyclo[2.2.1]heptane-2-carboxylic acid 9.3
Endothall 9.1
C8H8O5 9.1
C8H8O5 9.1
methyl 3,4,5-trihydroxybenzoate 8.9
Sanggenon C 8.9
FK520 8.7
C8H8O5 8.7
C15H10O5 8.5
FK506 8.5
C8H8O5 8.4
Aldophosphamide 8.3
F acid 8.3
Colistimethate sodium 8.1
Microcystin-LR 8.0
CL 72 7.9
Tetrachlorobisphenol A 7.9
Tetrachlorobisphenol A 7.9
2',4'-Dihydroxychalcone 7.9
2-hydroxydecanoic acid 7.9
Tellimagrandin I 7.9
7-oxabicyclo[2.2.1]heptane 7.7
Sugiol 7.7
5-Iodotubercidin 7.3
C6H12O6 7.3
Regulin 7.3
Propylamine 7.3
5-Iodotubercidin 7.3
5-chloro-8-quinolinol 7.3
5-Iodotubercidin 7.3
PC-4 7.2
5-Iodotubercidin 7.2
Nodularin 7.1
THPA 7.1
S152 7.0
AICA-riboside 6.9
Rapamycin 6.9
Turanose 6.8
Turanose 6.8
Cyclosporine 6.8
beta-tocopherol 6.7
Mycophenolate mofetil 6.7
CNA 6.6
Oleandrin 6.6
Regulin 6.5
Glycogen synthase 6.5
Phosphoserine 6.5
phosphoserine 6.5
threonine 6.5
Rubratoxin B 6.5
Phosphorylase a 6.5
CAN 6.2
bicyclo[2.2.1]heptane 6.0
diethyl phosphonate 6.0
Xylulose 6.0
4-tert-Octylphenol 6.0
4-methylquinazoline 6.0
Deoxyspergualin 5.9
more...