Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.1.3.16 (calcineurin)
17,112 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein calcineurin 8233 protein phosphatase 6862 phosphatase 3963 calmodulin 1785 Mol 1633 threonine 1611 Sep 1125 FK506 992 inhibitor 2 724 calcineurin inhibitor 693 PP2A 687 ATP 652 insulin 563 protein phosphatase-1 554 PP1 548 mTOR 433 cytokine 424 phosphoprotein 354 ATPase 311 MAPK 309 cAMP-dependent protein kinase 309 AMP 306 p38 287 endoplasmic reticulum 286 PKC 266 ERK 247 histone 210 p53 208 ERK1 206 PKA 203 glycogen synthase 203 protein phosphatase 2B 185 IL-2 183 myosin 181 caspase-3 181 CA1 178 CaMKII 177 nuclear factor of activated T-cells 176 FKBP12 175 MAP kinase 174 AKT 164 polypeptide 162 alpha isoform 159 JNK 159 cyclin 159 NMDA receptor 156 MEK 155 phosphodiesterase 155 tyrosine kinase 155 tumor necrosis factor 153 CD4 151 CNB 150 mitogen-activated protein 150 inhibitor-1 150 PI3K 146 ubiquitin 146 Bcl-2 145 PTEN 145 SDS 141 cyclophilin 141 proteasome 140 GSK 139 immunophilin 138 interleukin-2 133 phosphatidylinositol 3-kinase 132 alkaline phosphatase 130 extracellular signal-regulated kinase 129 PP2C 128 DARPP-32 128 angiotensin II 128 casein 125 TNF 123 AP-1 119 RCAN1 117 phosphorylating 113 phosphorylase kinase 111 interferon 109 TCR 108 CREB 108 AMP-activated protein kinase 108 more...

Disease cancer 1050 tumor 836 Alzheimer's disease 480 diabetes 369 hypertension 309 atopic dermatitis 267 heart failure 261 depression 225 renal disease 197 ischemia 195 tumorigenesis 155 hepatocellular carcinoma 155 leukemia 144 SDS 141 proteinuria 140 breast cancer 140 neuroblastoma 110 pruritus 109 HIV 106 graft-versus-host disease 106 skin disease 105 tumor growth 100 obesity 94 hepatitis C 94 carcinoma 93 Cryptococcus neoformans 90 Parkinson's disease 90 melanoma 87 psoriasis 87 Down syndrome 83 lymphoma 82 cardiovascular disease 82 hyperlipidemia 81 cytomegalovirus 80 systemic lupus erythematosus 78 type 2 diabetes 77 pertussis 75 cold 75 retinoblastoma 75 tumor progression 69 renal failure 69 nephrotic syndrome 68 prostate cancer 66 carcinogenesis 66 hyperglycemia 64 ATM 64 liver disease 63 dementia 62 virus infection 62 atherosclerosis 61 schizophrenia 61 glomerulosclerosis 58 immunodeficiency 57 lupus 57 heart disease 56 ventricular hypertrophy 56 stroke 55 asthma 54 glioma 53 epilepsy 52 dermatitis 52 cirrhosis 52 MCF 52 Blocking 51 rheumatoid arthritis 50 osteoporosis 50 autoimmune disease 50 skin cancer 49 encephalopathy 48 eczema 47 glioblastoma 46 chronic renal failure 46 cardiomyopathy 46 herpes simplex 45 squamous cell carcinoma 44 acute myeloid leukemia 44 fungal infection 44 anemia 44 infectious diseases 44 adenocarcinoma 43 more...

Symptom starvation 106 pain 90 seizures 85 diarrhea 37 erythema 32 collapse 27 fatigue 27 headache 23 rundown 20 functional recovery 17 tremor 17 weakness 16 vomiting 14 nausea 14 ataxia 13 exhaustion 12 anesthesia 10 dyspnea 9 memory loss 9 arthralgia 8 overweight 7 abdominal pain 7 discomfort 6 dry skin 6 hypothermia 6 stigma 6 acidity 6 discomfort 6 myoclonus 6 constipation 5 bone pain 5 dry eye 5 respiratory distress 5 cough 5 polyuria 5 agitation 5 insomnia 4 lethargy 4 acute stress 4 oliguria 4 analgesia 4 tense 3 angina 3 myalgia 3 paresthesia 3 hyperoxia 3 skin irritation 3 acute pain 3 cachexia 3 thinning 3 hypotonia 3 splenomegaly 3 twitching 2 chorea 2 dysesthesia 2 leg pain 2 anorexia 2 shortness of breath 2 dysarthria 2 Anoxia 2 dystonia 2 hepatomegaly 2 dysuria 2 disturbed balance 2 back pain 2 flushing 2 neuralgia 2 ENT 2 catatonia 2 cerebellar ataxia 2 blurred vision 2 CSR 2 photophobia 1 Vulvodynia 1 stridor 1 Gastrointestinal symptoms 1 neurological disability 1 No adverse effect 1 intention tremor 1 tenesmus 1 more...

Drug Dermatol 242 IL-2 183 Tacrolimus 178 lysine 81 MAP 73 IFN-gamma 57 caffeine 53 Cardiovasc 48 ROS 41 Gel 33 Pimecrolimus 33 Belatacept 31 CaCl2 30 CaCl2 30 CaCl2 30 Monit 29 Everolimus 29 Angiotensin II 27 CSF 27 Neoral 25 Forskolin 23 Dial 21 ABC 20 Rituximab 20 K-252a 17 Prograf 17 Campath 16 NADH 16 Leaf 16 Campath 16 CTX 15 Ethanol 15 Asn 15 Parkin 14 Parkin 14 Nephron 13 vitamin E 13 Trifluoperazine 12 Asthma 12 TAT 12 ascorbate 12 ICI 11 TAC 10 DNase I 10 Basiliximab 9 Basiliximab 9 EE2 9 ZnCl2 8 Rapamune 8 ZnCl2 8 Glutathione 8 Daclizumab 7 CAM 7 PCP 7 Allergen 7 Alanine 6 Arsenic trioxide 6 Histamine 6 CoCl2 5 CoCl2 5 Caspofungin 5 Capsicum 5 RFP 5 Mycophenolic acid 5 Glucagon 5 PTH 5 BH4 5 Fluconazole 5 Taxol 5 CDP 4 Doxycycline 4 Indomethacin 4 ROC 4 Adriamycin 4 nitroglycerin 4 MRC 4 SMP 4 Ginseng 4 Prednisolone 4 Prednisone 4 more...

Enzyme calcineurin 17112 protein kinase 2414 protein phosphatase 2A 1571 mitogen-activated protein kinase 1083 protein kinase C 999 AMPK 358 phosphorylase 356 ERK 333 ATPase 323 CaMKII 284 MEK 229 luciferase 185 GSK 169 phosphodiesterase 155 AMP-activated protein kinase 155 phospholipase C 150 focal adhesion kinase 148 caspase-3 142 proteasome 142 alkaline phosphatase 135 phosphatidylinositol 3-kinase 132 glutathione S-transferase 131 phosphorylase kinase 120 cdc2 115 trypsin 92 myosin light chain kinase 91 adenylate cyclase 78 acid phosphatase 75 thrombin 66 RNA polymerase 65 type 1 protein phosphatase 62 MAP 62 catalase 61 PKG 59 renin 56 superoxide dismutase 55 phosphoinositide 3-kinase 52 NO synthase 51 lactate dehydrogenase 48 tyrosine hydroxylase 46 AMPK 46 APC 44 P-glycoprotein 44 TOR 44 IKK 42 NADPH oxidase 41 PDE 40 PTPase 40 acetyl-CoA carboxylase 40 NADPH oxidase 39 guanylate cyclase 37 polo-like kinase 1 36 reverse transcriptase 36 caspase-8 35 peptidyl-prolyl cis-trans isomerase 34 phospholipase A2 31 PARP 31 pyruvate dehydrogenase 30 ACS 28 pyruvate kinase 28 MEKK1 27 caspase-9 27 PDK1 26 NOS 26 peroxidase 26 hexokinase 25 CYP3A4 25 pyruvate dehydrogenase 22 cellulose synthase 22 phosphoenolpyruvate carboxykinase 22 pyruvate dehydrogenase 22 glycogen synthase phosphatase 21 phosphoenolpyruvate carboxykinase 21 phosphoenolpyruvate carboxykinase 21 p-nitrophenylphosphatase 20 chymotrypsin 20 cathepsin K 20 chitin synthase 20 complex I 19 beta-galactosidase 19 more...

Compound calcium 3050 threonine 2110 serine 1947 Dec 1216 FK506 1137 DNA 1064 phosphate 741 cAMP 734 tyrosine 703 ATP 652 glucose 539 Clin 481 sodium 480 oxygen 362 AMP 317 acetate 307 Cyclosporine 301 Okadaic acid 301 water 291 glutamate 270 manganese 244 Mg2+ 222 Rapamycin 215 alanine 200 arginine 187 salt 179 creatinine 175 leucine 173 NMDA 172 nitric oxide 171 potassium 171 sulfate 154 SDS 151 cGMP 131 MEK 131 zinc 127 Cardiol 125 lysine 125 phosphoserine 125 cysteine 124 TNF 123 DEAE 116 hydrogen 116 Insulin 115 ethanol 104 AMPA 104 PMA 103 PMA 100 His 97 nitrogen 90 Asp 85 Phe 83 Calyculin A 83 GABA 80 GABA 80 glycerol 80 proline 78 methionine 78 GTP 78 ADP 74 ADP 72 SET 72 ADP 71 COS 68 MAP 68 Serine 65 EDTA 64 EDTA 64 galactose 63 vitamin D 61 Glycogen synthase 58 Ang II 56 nickel 56 Triton X-100 55 urea 53 ABA 53 caffeine 53 H2O2 52 ammonium 51 iron 49 more...

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