Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.16 (
calcineurin
)
17,112
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
calcineurin
8233
protein phosphatase
6862
phosphatase
3963
calmodulin
1785
Mol
1633
threonine
1611
Sep
1125
FK506
992
inhibitor 2
724
calcineurin inhibitor
693
PP2A
687
ATP
652
insulin
563
protein phosphatase-1
554
PP1
548
mTOR
433
cytokine
424
phosphoprotein
354
ATPase
311
MAPK
309
more...
Disease
cancer
1050
tumor
836
Alzheimer's disease
480
diabetes
369
hypertension
309
atopic dermatitis
267
heart failure
261
depression
225
renal disease
197
ischemia
195
tumorigenesis
155
hepatocellular carcinoma
155
leukemia
144
SDS
141
proteinuria
140
breast cancer
140
neuroblastoma
110
pruritus
109
HIV
106
graft-versus-host disease
106
more...
Symptom
starvation
106
pain
90
seizures
85
diarrhea
37
erythema
32
collapse
27
fatigue
27
headache
23
rundown
20
functional recovery
17
tremor
17
weakness
16
nausea
14
vomiting
14
ataxia
13
exhaustion
12
anesthesia
10
dyspnea
9
memory loss
9
arthralgia
8
more...
Drug
Dermatol
242
IL-2
183
Tacrolimus
178
lysine
81
MAP
73
IFN-gamma
57
caffeine
53
Cardiovasc
48
ROS
41
Pimecrolimus
33
Gel
33
Belatacept
31
CaCl2
30
CaCl2
30
CaCl2
30
Everolimus
29
Monit
29
Angiotensin II
27
CSF
27
Neoral
25
more...
Enzyme
calcineurin
17112
protein kinase
2414
protein phosphatase 2A
1571
mitogen-activated protein kinase
1083
protein kinase C
999
AMPK
358
phosphorylase
356
ERK
333
ATPase
323
CaMKII
284
MEK
229
luciferase
185
GSK
169
AMP-activated protein kinase
155
phosphodiesterase
155
phospholipase C
150
focal adhesion kinase
148
proteasome
142
caspase-3
142
alkaline phosphatase
135
more...
Compound
calcium
3050
threonine
2110
serine
1947
Dec
1216
FK506
1137
DNA
1064
phosphate
741
cAMP
734
tyrosine
703
ATP
652
glucose
539
Clin
481
sodium
480
oxygen
362
AMP
317
acetate
307
Cyclosporine
301
Okadaic acid
301
water
291
glutamate
270
more...