Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.3.16 (calcineurin)
17,112 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
calcineurin 8233
protein phosphatase 6862
phosphatase 3963
calmodulin 1785
Mol 1633
threonine 1611
Sep 1125
FK506 992
inhibitor 2 724
calcineurin inhibitor 693
PP2A 687
ATP 652
insulin 563
protein phosphatase-1 554
PP1 548
mTOR 433
cytokine 424
phosphoprotein 354
ATPase 311
MAPK 309
more...
Disease
cancer 1050
tumor 836
Alzheimer's disease 480
diabetes 369
hypertension 309
atopic dermatitis 267
heart failure 261
depression 225
renal disease 197
ischemia 195
tumorigenesis 155
hepatocellular carcinoma 155
leukemia 144
SDS 141
proteinuria 140
breast cancer 140
neuroblastoma 110
pruritus 109
HIV 106
graft-versus-host disease 106
more...
Symptom
starvation 106
pain 90
seizures 85
diarrhea 37
erythema 32
collapse 27
fatigue 27
headache 23
rundown 20
functional recovery 17
tremor 17
weakness 16
nausea 14
vomiting 14
ataxia 13
exhaustion 12
anesthesia 10
dyspnea 9
memory loss 9
arthralgia 8
more...
Drug
Dermatol 242
IL-2 183
Tacrolimus 178
lysine 81
MAP 73
IFN-gamma 57
caffeine 53
Cardiovasc 48
ROS 41
Pimecrolimus 33
Gel 33
Belatacept 31
CaCl2 30
CaCl2 30
CaCl2 30
Everolimus 29
Monit 29
Angiotensin II 27
CSF 27
Neoral 25
more...
Enzyme
calcineurin 17112
protein kinase 2414
protein phosphatase 2A 1571
mitogen-activated protein kinase 1083
protein kinase C 999
AMPK 358
phosphorylase 356
ERK 333
ATPase 323
CaMKII 284
MEK 229
luciferase 185
GSK 169
AMP-activated protein kinase 155
phosphodiesterase 155
phospholipase C 150
focal adhesion kinase 148
proteasome 142
caspase-3 142
alkaline phosphatase 135
more...
Compound
calcium 3050
threonine 2110
serine 1947
Dec 1216
FK506 1137
DNA 1064
phosphate 741
cAMP 734
tyrosine 703
ATP 652
glucose 539
Clin 481
sodium 480
oxygen 362
AMP 317
acetate 307
Cyclosporine 301
Okadaic acid 301
water 291
glutamate 270
more...