Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.3.16 (
calcineurin
)
17,112
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Acrodermatitis continua of Hallopeau is a rare subtype of pustular psoriasis that presents as a sterile, pustular eruption commonly in the finger tips and toes. This disease inflicts both the skin and nail bed, and causes severe disfigurement of the distal phalanges. Because it is a variant of pustular psoriasis,
acrodermatitis
continua of Hallopeau is commonly managed with antipsoriatic medications. Common approaches to treatment include topical therapy (corticosteroids, vitamin D analogs, and
calcineurin
inhibitors), systemic therapy, and in more severe cases, biologic therapy. This review will discuss how
acrodermatitis
continua of Hallopeau is diagnosed and how it is managed, with a particular emphasis on the use of biologics.
...
PMID:The Use of Biologic Therapy in the Treatment of Acrodermatitis Continua of Hallopeau: A Review. 3093 89
