Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.3.1 (alkaline phosphatase)
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Human Gene/Protein
Intelectin 1 9.4
transmembrane protein 199 9.4
alkaline phosphatase 9.4
alkaline phosphomonoesterase 9.4
BMP-8A 9.4
phosphomonoesterase 9.4
DLC-A 9.4
NF-kappa-B transcription factor p65 9.4
PERIOSTIN 9.4
homer homolog 1 9.4
inositoltrisphosphohydrolase 9.4
LECT1 protein 9.4
PIGX 9.4
semaphorin B 9.4
TMEM9 protein 9.4
C1orf19 9.4
TAP4 9.4
Alkaline phosphomonoesterase 8.8
TLAP 8.8
ALPL 8.6
PIGL 8.5
runt-related transcription factor 2 8.4
Peptidyl arginine deiminase, type IV 8.4
SATB homeobox 2 8.4
zinc finger protein 42 8.4
FAM46A protein 8.4
chondroitinsulfatase 8.4
SCYA18 8.4
LIPM 8.4
triphosphoinositide phosphodiesterase 8.4
collagen type X alpha 1 8.4
tissue-nonspecific ALP 8.4
coiled-coil domain containing 115 8.4
Cas-interacting zinc finger protein 8.4
orf 2 8.4
OSTERIX 8.3
TNAP 8.3
Phosphomonoesterase 8.3
osterix 8.3
osteocalcin 8.2
more...
Disease
Leontiasis 9.4
Adult hypophosphatasia 9.4
Primary cholangitis 9.4
Granulomatous liver disease 9.4
infected skin cyst 9.4
Neonatal rickets 9.4
Steroid-induced osteopenia 9.4
High turnover osteopathy 9.4
degeneration; spleen 9.4
Interstitial pancreatitis 9.4
Neutrophilic leukemia 9.4
Childhood hypophosphatasia 9.4
infected skin cyst 9.4
Disorder of vitamin D 9.4
hypophosphatasia 8.6
Hyperphosphatasemia 8.6
pyelophlebitis 8.4
Organic aciduria 8.4
Enzymopathy 8.4
Leukaemoid 8.4
Cribriform carcinoma 8.4
Eye disorder 8.4
Chronic active viral hepatitis 8.4
Gingival ulceration 8.4
Severe toxemia 8.4
Gallbladder infection 8.4
craniotabes 8.2
megalocytic anemia 7.8
Cold Ischemia 7.8
rheumatoidlike arthritis 7.8
monosomy 1p 7.8
Disseminated paracoccidioidomycosis 7.8
Looser-Milkman 7.8
Juvenile osteoporosis 7.8
Aluminum-related osteomalacia 7.8
IBD4 7.8
LACH 7.8
Paget's Disease 7.4
Suppurative cholangitis 7.4
Osteosarcoma of bone 7.4
more...
Symptom
Temporal headache 9.4
Moist rales 8.4
Pruritus of pregnancy 7.8
Osteoarticular pain 7.8
Left flank pain 7.1
musculoskeletal back pain 6.8
respiratory pain 6.6
Climacteric symptoms 6.4
jaundice of the skin 6.4
Breast tenderness 6.3
phosphatemia 6.2
bone pain 5.9
Gastrointestinal discomfort 5.8
Murphy's sign 5.8
febricula 5.5
Pain and tenderness 5.3
benign congenital hypotonia 5.2
Mucosal hyperplasia 5.1
hepatomegaly 4.9
carpopedal spasm 4.9
Kayser-Fleischer ring 4.8
right upper quadrant pain 4.7
redness of the eyes 4.6
dark urine 4.6
vaginal itching 4.3
Breast pain 4.2
No toxic effect 4.0
male puberty 3.9
musculoskeletal disability 3.9
hepatosplenomegaly 3.8
koilonychia 3.7
rundown 3.7
hypoproteinemia 3.7
emaciation 3.7
Beau's lines 3.6
Severe diarrhea 3.6
Flu-like symptoms 3.6
inanition 3.6
General symptoms 3.5
menopausal symptoms 3.3
more...
Drug
Fexaramine 9.4
Skelid 9.4
Flumetasone 9.4
Skelid 9.4
Basaljel 8.4
Netromycin 7.8
Anise oil 7.8
Elsamitrucin 7.8
Liarozole fumarate 7.4
Mentha oil 7.4
L-Homoarginine 7.3
Rocaltrol 7.2
Erythromycin acistrate 7.1
Parbendazole 7.1
Phosphonopyruvate 7.1
Sudoxicam 7.1
Fosfluconazole 7.1
S-Methylcysteine 6.8
Etidronate disodium 6.8
Iodamide 6.8
Cocarboxylase 6.6
Tocopherol acetate 6.6
Netilmicin sulfate 6.6
Epimedium herb 6.6
Actonel 6.6
Calcium acetate 6.6
Iopentol 6.3
Piriprost 6.3
Calcium acetate 6.3
EHDP 6.2
Chrysalin 6.2
Sevelamer hydrochloride 6.1
Levamisol 6.1
Hymenialdisine 6.1
Aquavan 6.1
PTH 6.0
Calcium silicate 6.0
Ipriflavone 6.0
Lactase 5.9
Calcium lactate 5.8
more...
Enzyme
glycerin-3-phosphate dehydrogenase 9.4
mannonate dehydrogenase 9.4
alkaline phosphatase 9.4
EC 1.1.99.10 8.8
dipeptidyl-dipeptidase 8.4
chondroitinsulfatase 8.4
EC 2.3.1.2 8.4
alkyllyso-GP:acetyl-CoA acetyltransferase 7.8
ketogluconate dehydrogenase 7.8
phosphoglycerol transferase 7.6
phosphatidylinositol N-acetylglucosaminyltransferase 7.4
fructose-2,6-bisphosphate 6-phosphatase 7.4
glucose-1-phosphatase 7.4
GPI-PLD 7.3
leucine aminopeptidase 7.2
EC 2.3.2.1 7.2
phosphonoacetate hydrolase 7.1
beta-glycerophosphatase 7.1
uronate isomerase 7.1
ADPR-PPase 7.1
acid phosphatase 7.0
gamma-glutamyl transpeptidase 7.0
sucrase 7.0
venom phosphodiesterase 6.8
nucleotide pyrophosphatase 6.8
EC 3.6.1.28 6.8
hippurate hydrolase 6.8
aspartate aminotransferase 6.8
5'-nucleotidase 6.8
alanine aminopeptidase 6.7
phosphoamidase 6.7
3'(2'),5'-bisphosphate nucleotidase 6.7
PLP phosphatase 6.6
glycerophosphate phosphatase 6.6
D-galactose dehydrogenase 6.6
FAD-AMP lyase 6.6
alanine aminotransferase 6.5
lactase 6.4
nucleotidase 6.3
PHOSPHO1 6.2
more...
Compound
Fagaronine chloride 9.4
o-Nitrophenyl beta-D-galactopyranoside 9.4
CaO-6 9.4
Eremanthin 9.4
Fast Red TR Salt 9.4
ethyl 4-(1H-indol-3-yl)butanoate 9.4
Adenosine 2',5'-bisphosphate 9.4
Fexaramine 9.4
Naphthol AS-BI 8.6
Nitrophenylphosphate 8.4
2-deoxypentitol 8.4
1,5-diiodopentane 8.4
Pseudopurpurin 8.4
2-naphthyl laurate 8.4
Gemcadiol 8.4
Inositol 1,2-cyclic phosphate 8.4
C18H28N5O19P3 8.4
Calophyllolide 8.4
butanohydrazide 8.4
New Fuchsin 8.2
Fast Red TR 8.1
Deoxypyridinoline 7.9
Alizarin 7.8
Methabenzthiazuron 7.8
Piperazine adipate 7.8
Irilone 7.8
Neoeriocitrin 7.8
Cupressuflavone 7.8
Alizarin Red S 7.7
2-amino-2-methyl-1-propanol 7.5
2-amino-2-methyl-1-propanol 7.4
Carfentrazone-ethyl 7.4
Gum karaya 7.4
Substance B 7.4
N'-(4-hydroxy-3-methoxybenzylidene)isonicotinohydrazide 7.4
4-methoxy-1-naphthaldehyde 7.4
4-methylbenzenesulfonohydrazide 7.4
hydroxymethylphosphonic acid 7.2
Sciadopitysin 7.1
9-acridinecarboxylic acid 7.1
more...