Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.1.3.1 (alkaline phosphatase)
47,916 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein alkaline phosphatase 47441 osteocalcin 4989 osteogenic 4365 collagen 3347 Sep 3234 aspartate aminotransferase 3151 alanine aminotransferase 2307 acid phosphatase 2118 lactate dehydrogenase 1970 Mol 1891 albumin 1833 parathyroid hormone 1744 type I collagen 1441 osteopontin 1359 phosphatase 1216 catalase 1120 superoxide dismutase 1112 Alkaline phosphatase 1062 ALP 833 ATP 805 bone morphogenetic protein 800 BMP-2 800 peroxidase 777 hemoglobin 740 bone sialoprotein 712 ATPase 702 insulin 701 brush border 667 PTH 659 glutathione peroxidase 631 tartrate-resistant acid phosphatase 616 serum albumin 593 gamma-glutamyl transpeptidase 586 GSH 586 osteosarcoma 563 esterase 507 5'-nucleotidase 496 gamma-glutamyltransferase 489 osteoprotegerin 482 calcitonin 475 creatine kinase 462 amylase 455 runt-related transcription factor 2 417 tumor necrosis factor 413 TNF 406 RUNX2 403 SDS 396 cytokine 394 osterix 392 Osteocalcin 391 lysozyme 380 AST 379 fused 371 AMP 365 endoplasmic reticulum 361 leucine aminopeptidase 352 membrane-bound 336 glycoprotein 332 osteonectin 326 fibronectin 324 gut 319 phosphomonoesterase 318 catenin 309 polypeptide 309 RANKL 306 IL-6 300 phosphodiesterase 292 LDH 287 lipopolysaccharide 287 glutamate pyruvate transaminase 280 prothrombin 279 lipase 275 intestinal alkaline phosphatase 274 beta-glucuronidase 274 CTX 269 lactase 269 p38 256 collagenase 254 vascular endothelial growth factor 249 myeloperoxidase 248 GPT 247 interleukin-6 244 adenosine triphosphatase 241 OCT4 235 microsomal 234 parathormone 231 gamma-glutamyltranspeptidase 231 C-reactive protein 230 lectin 229 placental alkaline phosphatase 228 acetylcholinesterase 225 GTG 224 membrane protein 223 glucose-6-phosphatase 219 She 214 glutathione reductase 214 kit 212 chronic renal failure 211 estrogen receptor 209 lymphoid 207 BMP2 206 aminopeptidase 203 type I procollagen 200 growth hormone 198 Pseudomonas 197 Nanog 195 proteoglycan 189 serum protein 188 carcinoembryonic antigen 183 Oct4 180 TCP 180 ERK1 179 caspase-3 177 ADP 176 ALPL 175 NMR 174 casein 173 HDL 173 thymus 172 fibrinogen 170 glucose-6-phosphate dehydrogenase 169 Smad1 168 TGF-beta 167 ROS 165 MAPK 165 transferrin 161 GGT 161 ACS 160 Pol 159 ash 159 ferritin 156 type X collagen 155 glutathione S-transferase 155 adenylate cyclase 154 GTP 154 epidermal growth factor 153 BMP4 153 Acid phosphatase 152 alpha-fetoprotein 152 ERK 150 Gen 149 SOD 148 glucosidase 146 BMD 145 vimentin 145 type II collagen 144 interferon 143 IGF-I 143 IgA 142 neuraminidase 141 insulin-like growth factor 140 Runt-related transcription factor 2 139 proximal tubule 138 BGP 136 peptidase 134 matrix protein 132 glutamate dehydrogenase 132 reductase 130 granulocyte 130 threonine 129 more...

Disease osteoporosis 1992 cancer 1826 tumor 1604 bone disease 680 cholestasis 658 osteosarcoma 616 diabetes 608 hyperparathyroidism 595 GSH 586 liver disease 585 carcinoma 535 metastases 512 cirrhosis 503 osteomalacia 455 PDB 449 SDS 396 hepatitis 387 hypercalcemia 381 rickets 373 hypophosphatasia 348 anemia 345 breast cancer 341 hepatocellular carcinoma 334 SEM 318 primary biliary cirrhosis 289 leukemia 280 prostate cancer 273 CTX 271 cholangitis 264 pruritus 259 vitamin D deficiency 258 chronic renal failure 251 bone metastases 240 adenocarcinoma 234 hypertension 220 rheumatoid arthritis 212 primary hyperparathyroidism 206 cold 188 renal disease 188 renal osteodystrophy 185 HIV 182 depression 181 renal failure 181 osteoarthritis 179 TCP 179 multiple myeloma 177 lymphoma 172 thrombocytopenia 170 obesity 168 Best 166 sepsis 164 hepatitis B 160 ash 159 periosteum 158 uterus 156 arthritis 146 BMD 145 atherosclerosis 145 carcinogenesis 142 liver fibrosis 141 chronic myeloid leukemia 141 chronic hepatitis 138 hepatitis C 136 sepsis 136 cytomegalovirus 133 fatty liver 128 dysplasia 127 immunodeficiency 127 PCL 125 Alzheimer's disease 124 hyperglycemia 123 hyperthyroidism 123 gallstones 122 viral hepatitis 122 primary sclerosing cholangitis 119 pancreatitis 119 type 2 diabetes 118 colon cancer 117 periodontitis 117 hyperbilirubinemia 117 adenoma 116 hyperphosphatemia 116 malnutrition 115 infectious diseases 113 ischemia 113 liver metastases 112 biliary obstruction 108 tuberculosis 107 obstructive jaundice 106 colorectal cancer 103 plaque 102 AIDS 99 chronic liver disease 96 Hodgkin's disease 95 cystic fibrosis 95 proteinuria 93 acute myeloid leukemia 91 epididymis 90 hypercalciuria 90 lung cancer 89 osteitis 87 inflammatory bowel disease 87 ulcerative colitis 87 hypercholesterolemia 83 malabsorption 82 Mycobacterium 81 osteodystrophy 79 cholera 79 hyperlipidemia 78 cardiovascular disease 77 celiac disease 76 melanoma 76 lymphadenopathy 75 sarcoma 74 eosinophilia 72 portal hypertension 72 virus infection 72 epilepsy 72 neutropenia 71 OHD 71 liver cancer 71 systemic lupus erythematosus 71 teratoma 70 MCF 70 tumor growth 69 TEM 68 TEM 67 Infection 67 acute hepatitis 66 pneumonia 64 alcoholism 64 LAP 63 postmenopausal bone loss 63 colitis 63 worms 63 Schistosoma mansoni 62 primary tumor 62 hypoparathyroidism 62 tumorigenesis 62 chronic active hepatitis 62 osteogenesis imperfecta 61 hypothyroidism 61 rash 61 Epstein 61 stroke 61 heart failure 60 Graves' disease 59 renal cell carcinoma 58 leukopenia 58 Crohn's disease 57 amyloidosis 57 West 57 hypovitaminosis 56 cholecystitis 56 gastric cancer 56 epiphysis 56 Hepatotoxicity 56 DDP 55 sarcoidosis 54 osteosclerosis 54 more...

Symptom pain 519 diarrhea 294 bone pain 279 hepatomegaly 258 abdominal pain 219 weakness 190 fatigue 184 vomiting 168 anorexia 160 splenomegaly 136 starvation 134 anesthesia 121 seizures 119 nausea 113 hepatosplenomegaly 93 headache 65 lethargy 58 back pain 54 Ill 53 arthralgia 42 dyspnea 40 chills 39 collapse 38 polyuria 38 constipation 36 nausea and vomiting 35 thinning 34 myalgia 33 epigastric pain 32 overweight 30 low back pain 30 discomfort 30 discomfort 30 respiratory distress 28 cough 28 flushing 27 hypotonia 27 distraction 27 right upper quadrant pain 26 erythema 25 menopausal symptoms 25 polydipsia 25 ataxia 23 hypoproteinemia 22 colic 22 dizziness 20 asthenia 20 emaciation 20 insomnia 19 agitation 18 hypothermia 17 exhaustion 17 acidity 16 cachexia 16 fever of unknown origin 15 chest pain 14 hot flushes 13 decreased appetite 13 sleepiness 13 regurgitation 12 phosphatemia 12 angina 12 pallor 12 night sweats 12 tremor 11 abdominal discomfort 11 analgesia 10 leg pain 10 dark urine 10 acute abdominal pain 10 paresthesia 10 hyperoxia 10 rundown 10 Stiffness 9 hip pain 8 numbness 8 Wind 8 hot flashes 7 dysuria 7 acute stress 6 apathy 6 nasal discharge 6 rigors 6 Decreased activity 6 paresis 6 Gastrointestinal symptoms 6 exertional dyspnea 5 tachypnea 5 hypercapnia 5 vertigo 5 blurred vision 5 Murphy's sign 5 incoordination 5 spasticity 5 oliguria 5 clubbing 5 limb pain 5 abdominal cramps 5 cyanosis 5 functional recovery 4 memory loss 4 hoarseness 4 hunger 4 tinnitus 4 inanition 4 shortness of breath 4 bloating 4 heartburn 4 abnormal gait 4 microbial colonization 4 Spots 4 sore throat 4 prostatism 4 Climacteric symptoms 4 shoulder pain 3 asterixis 3 spasm 3 stridor 3 syncope 3 hyperemesis gravidarum 3 swollen joints 3 dry skin 3 Kayser-Fleischer ring 3 tonic-clonic seizure 3 intestinal bleeding 3 mastalgia 3 Welt 3 thigh pain 3 fasciculation 3 eds 3 lassitude 3 acute abdomen 3 urinary frequency 3 tingling 3 hemoptysis 3 Breast tenderness 2 generalized pain 2 No adverse effect 2 stomach pain 2 bradypnea 2 body pain 2 renal colic 2 neck pain 2 masculinization 2 tense 2 male puberty 2 wheezing 2 muscle stiffness 2 dysarthria 2 dystonia 2 muscle cramps 2 Breast pain 2 No toxic effect 2 impaired motor coordination 2 prostration 2 myoclonus 2 excessive sweating 2 loin pain 2 chronic back pain 2 abdominal fullness 2 more...

Drug PTH 670 CTX 299 ascorbate 279 CTX 269 CTX 269 lysine 219 vitamin E 175 ROS 165 Dermatol 127 NADH 126 Dial 93 NBT 91 lactose 89 Gel 85 CSF 69 Monit 68 Nephron 66 TiO2 62 Nephron 58 EHDP 56 MAP 56 ICI 55 Ethanol 55 ZnO 53 Leaf 53 caffeine 51 IL-2 48 Albumin 47 EE2 46 DNase I 45 ABC 43 Retinoic acid 42 Cardiovasc 37 Serum albumin 36 ROC 33 Gelatin 33 citric acid 33 Glutathione 33 Fluorescein 33 CaCl2 32 Zoledronic acid 32 NAG 31 IFN-gamma 31 CaCl2 31 CaCl2 31 APD 31 Simvastatin 30 Asn 29 Vitamin E 28 pyridoxal phosphate 28 SiO2 27 Lactase 25 Indomethacin 25 MRC 25 G418 25 Alanine 24 Pronase 24 Amifostine 23 ampicillin 23 Paraffin 22 Prednisolone 22 Fluorescein 22 ZnCl2 22 ZnCl2 22 Activin 21 Vitamin K 21 Adriamycin 20 PDL 19 Bifidobacterium 19 G-CSF 19 ALA 19 Raloxifene 19 CDP 18 Growth hormone 18 Mutagen 18 Growth hormone 18 Zoledronic acid 17 Vitamin B 17 Glycyrrhiza 16 HCG 16 Estrogens 15 NH3 15 Portal 14 Fraction 14 p75 13 Vitamin A 13 Aloe 13 FAD 12 IL-11 12 Acacia 12 Ipriflavone 12 Teriparatide 11 CAM 11 Salmon calcitonin 11 Lactose 11 Vitamin B12 11 Fructose 10 DEX 10 Premarin 10 ENT 10 HCH 10 Ibandronate 10 Forskolin 10 Rocaltrol 10 Phenytoin 10 Lovastatin 10 Rutin 10 Bayer 10 Bortezomib 9 AZT 9 Ouabain 9 TAT 9 Zoladex 9 Histamine 9 L-tyrosine 9 EPA 9 Zoladex 9 Glucagon 9 Prednisone 9 Etoposide 9 Diurnal 9 beta-Galactosidase 9 TAK 9 ETA 9 Denosumab 9 nitroglycerin 8 Biopolymers 8 DPA 8 Pravastatin 8 Isotretinoin 8 niacin 8 Cinacalcet 8 Fipronil 8 Theophylline 8 AZT 8 Silica 7 PCB 7 Cibacron Blue 7 DHT 7 Rosiglitazone 7 Levamisol 7 Ketoconazole 7 Hypaque 7 Cimetidine 7 Vitamin K2 7 Glycerol 7 Calcium silicate 7 Hypaque 7 Cimetidine 7 Isoniazid 7 ACT 7 balanced salt solution 7 -deoxyadenosine 7 Galactose 7 Norplant 6 CoCl2 6 ADM 6 Myricetin 6 Emodin 6 CoCl2 6 more...

Enzyme alkaline phosphatase 47916 alanine aminotransferase 3647 aspartate aminotransferase 3559 acid phosphatase 2507 lactate dehydrogenase 2278 gamma-glutamyl transpeptidase 1743 superoxide dismutase 1177 catalase 1165 peroxidase 1109 ATPase 957 glutathione peroxidase 637 creatine kinase 613 protein kinase 613 mitogen-activated protein kinase 549 5'-nucleotidase 517 invertase 504 sucrase 455 acetylcholinesterase 432 ERK 418 alpha-glucosidase 399 lysozyme 390 AST 378 trypsin 364 leucine aminopeptidase 360 phosphodiesterase 359 beta-galactosidase 359 succinate dehydrogenase 301 lipase 285 cholinesterase 281 collagenase 275 protein kinase C 269 luciferase 268 lactase 264 beta-glucuronidase 261 phospholipase C 254 urease 241 urease 240 CD13 231 glucose-6-phosphatase 220 glutathione reductase 209 glutathione S-transferase 205 glucose-6-phosphate dehydrogenase 190 reverse transcriptase 168 adenylate cyclase 164 neuraminidase 162 RNase 160 ACS 160 RNase 156 glutamate dehydrogenase 142 glutamate dehydrogenase 142 glutamate dehydrogenase 141 focal adhesion kinase 137 caspase-3 135 calcineurin 135 succinic dehydrogenase 129 nucleotidase 125 phospholipase A2 125 malate dehydrogenase 123 alanine aminopeptidase 117 transpeptidase 117 cathepsin K 104 chymotrypsin 103 AMPK 99 DNase 99 beta-glucosidase 97 sulfatase 97 sorbitol dehydrogenase 97 thrombin 97 trehalase 97 alpha-amylase 95 prostate-specific antigen 95 aldolase 94 ceruloplasmin 94 RNA polymerase 91 hyaluronidase 91 diaphorase 87 thromboplastin 86 phytase 83 phytase 83 venom phosphodiesterase 80 alcohol dehydrogenase 80 beta-glucosidase 80 carbonic anhydrase 79 sucrase-isomaltase 77 hyaluronidase 77 ribonuclease 76 ribonuclease 75 beta-lactamase 75 ACE 72 isocitrate dehydrogenase 72 carboxylesterase 71 NQO1 69 DNA polymerase 68 elastase 67 MDP 66 cytochrome oxidase 66 nucleotide pyrophosphatase 64 glucose oxidase 64 p-nitrophenylphosphatase 63 phosphorylase 62 hexosaminidase 62 lipoprotein lipase 62 endonuclease 61 xanthine oxidase 61 MEK 61 CD10 60 tyrosinase 60 dipeptidyl peptidase IV 60 NADPH-diaphorase 60 pepsin 59 alpha-mannosidase 58 proteasome 58 thymidine kinase 58 papain 58 isocitrate dehydrogenase 57 arylsulfatase 57 apyrase 57 hexokinase 56 diaphorase 52 adenosine deaminase 51 glucoamylase 50 proteinase K 49 pyruvate kinase 49 adenosine deaminase 49 polynucleotide kinase 48 monoamine oxidase 47 cellulase 46 phosphatidylinositol 3-kinase 46 renin 44 GSK 44 transcriptase 43 phospholipase D 43 transglutaminase 42 AMP-activated protein kinase 42 carboxypeptidase Y 41 Mg2+-ATPase 39 CPR 39 glyceraldehyde-3-phosphate dehydrogenase 38 cathepsin D 38 demethylase 37 ornithine decarboxylase 37 micrococcal nuclease 37 nitrate reductase 36 nitrate reductase 36 P-glycoprotein 36 nitrate reductase 35 nitrate reductase 35 nitrate reductase 35 nitrate reductase 35 ADPase 34 glyceraldehyde-3-phosphate dehydrogenase 34 glyceraldehyde-3-phosphate dehydrogenase 33 NO synthase 32 arginase 31 cathepsin B 31 phosphoglucose isomerase 31 3'-exonuclease 30 SPC 30 glyceraldehyde-3-phosphate dehydrogenase 30 ATP synthase 30 more...

Compound calcium 7240 phosphate 5163 Dec 3301 Clin 3215 DNA 2952 creatinine 2281 glucose 2122 phosphorus 2095 sodium 2088 urea 1748 water 1655 vitamin D 1310 nitrogen 1098 zinc 1050 ALP 833 ATP 806 oxygen 801 alanine 757 sulfate 713 potassium 699 titanium 675 GSH 612 GSH 612 acetate 611 iron 574 MTT 502 ethanol 476 salt 447 cAMP 440 SDS 429 Mg2+ 425 TNF 406 copper 404 AMP 398 galactose 386 Alizarin 383 Phe 369 nitric oxide 358 arginine 352 leucine 343 serine 329 EDTA 309 lysine 309 EDTA 308 CTX 299 tyrosine 295 retinoic acid 278 His 260 hydrogen 260 carbonate 257 cysteine 257 cadmium 256 GPT 247 silver 235 PEG 229 CCl4 218 bromide 214 Triton X-100 210 Collagen 209 proline 207 threonine 207 methionine 204 glutamate 201 ammonium 198 ADP 194 manganese 191 aluminum 190 glycerol 189 Vitamin D 186 TCP 179 TCP 179 TCP 179 TCP 179 nitrate 177 ADP 176 ADP 176 PEG 174 DEAE 169 CO2 168 Asp 162 25-dihydroxycholecalciferol 160 ACS 160 methanol 160 ACS 160 GTP 157 ammonia 155 strontium 154 BMD 145 HCl 143 Gly 140 cobalt 138 phenol 134 selenium 134 Tris 132 silicon 132 NH2 131 acrylamide 131 phosphoric acid 130 Alizarin Red S 130 NADH 126 NAD 122 Estrogen 118 iodine 115 PPi 114 Tris 113 dUTP 111 hyaluronic acid 106 hydroxide 104 tryptophan 104 Insulin 104 NAD 101 H2O2 101 PGE2 101 NBT 99 tryptophan 96 tryptophan 93 tryptophan 93 Dial 92 nickel 92 mercury 91 NADPH 89 formaldehyde 88 acetone 88 NADPH 88 MDA 88 glutamine 87 Dexamethasone 85 phosphoserine 85 PAS 84 fluorine 82 TSH 82 COS 81 chloroform 81 alcohol dehydrogenase 80 chromium 80 TEM 78 adenylate 75 25-hydroxycholecalciferol 74 nicotinamide 73 APAP 73 Estrogen 72 oxalate 72 xylose 72 Cholesterol 70 acetic acid 69 CAT 69 MgCl2 68 DMSO 68 Lactate 68 formaldehyde 68 CAT 67 uridine 67 CAT 67 aldehyde 67 Alendronate 66 ASA 66 aspartic acid 66 Ascorbic acid 66 Optimal 64 Alendronate 64 more...

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