Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.1.3.1 (alkaline phosphatase)
 47,916 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

142 determinations of leucocyte alkaline phosphatase (LAP) activity have been done in 103 cases of high risk pregnancy. A statistically significant elevation of LAP score has been found in high risk pregnancies due to diabetes mellitus, toxaemia, renal diseases and third trimester haemorrhage, but not in pregnancies complicated by cardiac disease, chronic hypertension, Rh sensitization or anaemia.
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PMID:Leucocyte alkaline phosphatase activity during high risk pregnancies. 67 79

The accuracy of urinary oestriol and serum levels of human placental lactogen (HPL) and heat stable alkaline phosphatase (HSAP) as indicators of feto-placental function was studied in 76 patients with high risk pregnancy. Feto-placental dysfunction was predicted correctly by plasma HPL in 80%, by urinary oestriol in 70%, by serum HSAP in 47%, and by the complementary use of HPL and oestriol in 90% of the cases. Normal fetoplacental function was predicted correctly by plasma HPL in 94%, by urinary oestriol in 96%, by serum HSAP in 80%, and by the complementary use of oestril and HPL in 100% of the patients. The probability of feto-placental dysfunction with a pathological value was 88% with urinary oestriol, 84% with plasma HPL and 100% with the parallel use of oestriol and HPL. A normal value assured undisturbed feto-placental function in 89% with urinary oestriol, in 92% with plasma HPL and in 96% with the parallel use of oestriol and HPL.
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PMID:Urinary oestriol and serum activities of human placental lactogen and heat stable alkaline phosphatase as indicators of fetoplacental function. 115 5