Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.27.4 (ribonuclease)
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Human Gene/Protein
truncated lactoferrin 12.2
FLJ35220 protein 12.2
HEPN1 12.2
RNASE4 protein 12.2
RNase k6 11.4
modulator recognition factor 1 11.2
beta1,4GalNAc-T 11.2
cystatin pseudogene 11.2
SPINT4 11.2
RNase kappa 11.2
ribonuclease 4 10.9
RNH1 10.8
PARN 10.7
C20orf72 10.6
EXOSC2 10.6
ALDR1 10.6
ZFY protein 10.6
TM4SF1 protein 10.6
Eosinophil-derived neurotoxin 10.6
SUPV3L1 10.5
RNase 4 10.4
ERN2 10.2
Kcn1 10.2
gene trap ankyrin repeat 10.2
CDKN2AIPNL 10.2
RNase 8 10.2
T-complex protein 1 subunit beta 10.2
RNASET2 10.1
Ribonuclease T2 10.1
EDN 10.0
ribonuclease A 10.0
eosinophil-derived neurotoxin 9.9
Mtr3p 9.9
endothelial-overexpressed lipopolysaccharide-associated factor 1 9.9
N-acetylneuraminate pyruvate lyase 9.6
cytochrome c oxidase subunit VIa 9.6
EIF4E2 9.6
His-domain protein tyrosine phosphatase 9.6
tubulin alpha 6 9.6
PABP4 9.6
XPMC2 9.6
placental protein 11 9.6
IGF-binding protein 6 9.6
Angiogenin 9.6
Ribonuclease 9.6
CNOT8 9.5
ribonuclease T2 9.5
POLE1 9.4
Ribosomal protein L1 9.4
Protein disulfide-isomerase 9.4
PAPD5 9.4
EXOSC3 9.3
RNase A 9.3
NACA3 9.2
SAMS2 9.2
MGC-24 9.2
L-H2 9.2
Nuclear apoptosis-inducing factor 1 9.2
ribonuclease/angiogenin inhibitor 1 9.2
CNOT6L 9.2
deoxyribonuclease 9.1
retinoid X receptor-gamma 9.1
Fas-associating protein 9.1
PNLDC1 9.1
PHP2 9.1
DGKdelta 9.1
ETF1 9.1
hPop5 9.1
MTND6 9.1
apolipoprotein A-I binding protein 9.1
RRP12 9.1
RNase 7 9.0
RNASE1 9.0
PRI 9.0
RNase E 8.9
RRP44 8.9
Staphylococcal nuclease domain-containing protein 1 8.9
EXD2 8.9
ribonuclease/angiogenin inhibitor 8.9
DEDD 8.9
more...
Disease
adult pineoblastoma 12.2
Molybdenum deficiency 10.6
HBN1 10.2
Hepatic hemosiderosis 9.9
ovarian mixed germ cell tumor 9.1
Pineoblastoma 8.4
IGHD II 8.2
monosomy 8p 8.1
Porencephaly 7.8
HPC1 7.2
Lassa virus infection 7.1
Ichthyosis vulgaris 7.0
KNS 7.0
Perlman syndrome 6.9
latent virus infection 6.8
PPR1 6.8
mouse leukemia P388 6.6
Pancreatic necrosis 6.6
bacterial dysentery 6.5
Spring viremia of carp 6.5
nRNA 6.4
CMCT 6.3
Giant cell myocarditis 6.3
trichomonal vaginitis 6.3
white muscle disease 6.2
SAMS 6.0
Visna 6.0
mixed connective tissue disease 5.9
PIN 5.9
pinguecula 5.8
FAB M1 5.8
Stretches 5.8
Acute necrotizing pancreatitis 5.7
ARH 5.6
alcoholic myopathy 5.5
Chronic progressive external ophthalmoplegia 5.4
Fungal keratitis 5.2
RPC 5.2
Turcot syndrome 5.1
Hypereosinophilic syndrome 5.1
PIN 5.1
toxic nodular goiter 5.0
DIA 4.9
CMTX 4.9
ISD 4.9
STY 4.9
myeloblastosis 4.9
Friend leukemia 4.8
bacterial sinusitis 4.8
DHD 4.8
WSN 4.8
WSN 4.8
Minimal change disease 4.8
DHD 4.8
chondrodysplasia 4.8
coproporphyria 4.7
sclerodactyly 4.7
Toxoplasma encephalitis 4.7
Postoperative cognitive dysfunction 4.7
Sertoli-Leydig cell tumor 4.7
Sertoli-Leydig cell tumor 4.7
Papillomas 4.7
Malassez 4.6
macromastia 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
AT3 4.6
malignant mesothelioma 4.6
Vesicular stomatitis 4.5
pineoblastoma 4.5
thalassemia minor 4.5
Allergic bronchopulmonary aspergillosis 4.5
Hymenolepis 4.4
T-cell deficiency 4.4
more...
Symptom
RNA marker 7.6
female puberty 5.3
POA 4.2
autodigestion 3.9
Halo 3.4
starvation 3.0
muscle rigidity 2.2
physical appearance 1.7
hyperoxia 1.5
masculinization 0.9
Ill 0.8
HSA 0.7
collapse 0.4
arthralgia 0.4
dysarthria 0.4
chills 0.2
exhaustion 0.1
acidity -0.1
ataxia -0.1
cachexia -0.2
hypotonia -0.3
agitation -0.3
flushing -0.4
weakness -1.4
stigma -1.5
anorexia -1.5
hypothermia -1.8
tremor -1.9
respiratory distress -2.0
discomfort -2.2
discomfort -2.3
fatigue -2.4
seizures -2.5
dyspnea -2.5
diarrhea -2.6
anesthesia -2.9
pain -3.2
Drug
Onconase 10.9
Mitogillin 10.9
6-Methylpurine 8.9
7-Methylguanosine 8.6
Pronase 7.3
Bicine 7.2
Peanut oil 7.1
Arlacel 6.9
Gly-Tyr-Gly 6.8
Astragali radix 6.6
Pregnyl 6.2
Sodium acetate 5.5
Guanidine 5.4
Guanidine 5.4
Trapidil 5.4
Cytidine 5.4
TPV 5.4
KGF 5.3
Protamine sulfate 5.3
Vanilla 5.1
Eptifibatide 5.1
RBT 5.1
Bentonite 4.7
Papain 4.7
Asn 4.6
Lupron 4.6
R-gene 4.6
FCV 4.4
Kaolin 4.3
Sodium alginate 4.3
Lactase 4.1
CED 4.1
R1881 3.9
Doyle 3.6
-deoxyadenosine 3.5
Aminoguanidine 3.5
Gel 3.5
Fraction 3.5
anti-RSV 3.4
ISP 3.3
Silica 3.3
EE2 3.3
DNase I 3.3
Thyroglobulin 3.3
Glutamic acid 3.2
lysine 3.2
Biopolymers 3.2
Troglitazone 3.2
TES 3.1
CDP 3.0
CPM 3.0
VCR 2.9
Glide 2.9
Forskolin 2.9
ADR 2.8
ETA 2.8
IFN-beta 2.7
Fragment 2.6
VCR 2.6
AGG 2.6
DM1 2.6
Albumin 2.6
Rosiglitazone 2.6
Retinoic acid 2.5
PTH 2.5
Gelatin 2.5
Methylprednisolone 2.4
DEX 2.4
Aprotinin 2.4
Oxaliplatin 2.4
DFP 2.4
Alanine 2.4
Monensin 2.3
Cetuximab 2.3
p75 2.3
Growth hormone 2.3
Growth hormone 2.2
Luteinizing 2.2
CTC 2.2
AraC 2.2
more...
Enzyme
ribonuclease 12.2
ribonuclease 12.2
yeast ribonuclease 11.6
RNase 10.9
RNase 10.8
EC 2.1.1.31 10.6
ribonuclease alpha 10.4
EC 2.1.1.32 10.2
tRNA sulfurtransferase 9.9
deoxyribonuclease 9.7
deoxyribonuclease 9.6
poly(A)-specific ribonuclease 9.4
RNase T1 9.3
alpha-sarcin 9.1
RNase D 8.8
exoribonuclease 8.6
oligoribonuclease 8.6
RNase M5 8.4
glutathione-insulin transhydrogenase 8.4
polynucleotide phosphorylase 8.2
isochorismatase 8.0
protein disulfide-isomerase 7.9
D-galactose dehydrogenase 7.8
3'-phosphatase 7.8
RNase III 7.8
RNase PH 7.8
cytochrome b6/f complex 7.6
venom phosphodiesterase 7.6
EC 2.3.1.29 7.5
DNase 7.5
3'-exonuclease 7.5
8-amino-7-oxononanoate synthase 7.5
poly(A)-specific ribonuclease 7.3
protein methylase II 7.3
DNase II 7.1
methionine decarboxylase 7.1
RNase H 7.1
thiogalactoside transacetylase 7.0
coagulation factor XIa 7.0
tRNase Z 6.8
Rab geranylgeranyltransferase 6.8
pyroglutamyl peptidase II 6.7
RNase P 6.6
valyl-tRNA synthetase 6.6
CBPP 6.6
PGE2-9-ketoreductase 6.6
alanyl-tRNA synthetase 6.5
beta-glycerophosphatase 6.5
RNA ligase 6.4
sterol carrier protein 6.4
PNGase F 6.4
CobB 6.3
lactose synthetase 6.3
endodeoxyribonuclease 6.1
arginyl-tRNA synthetase 6.1
stringent factor 6.1
cathepsin C 6.0
poly(A) polymerase 5.9
polynucleotide kinase 5.8
plasmepsin II 5.8
endothiapepsin 5.7
glucosidase II 5.7
adenine deaminase 5.6
elongation factor (EF) 5.6
HC-Pro 5.6
glutamyl-tRNA reductase 5.5
lambda exonuclease 5.5
lysozyme 5.5
beta-1,4-galactosyltransferase 5.5
tryptophanyl-tRNA synthetase 5.5
S1 nuclease 5.4
ficin 5.4
chymosin 5.4
alpha-N-acetylglucosaminidase 5.3
purine nucleoside phosphorylase 5.3
aminopeptidase I 5.3
xyloglucan endotransglycosylase 5.3
sulfhydryl oxidase 5.3
GAR 5.3
glycyl-tRNA synthetase 5.3
more...
Compound
5-aminotryptophan 12.2
Diguanosine triphosphate 12.2
3-Aminoquinoline 11.2
p-Aminobenzoylglutamic acid 11.2
Pyridine borane 10.6
3'-UMP 9.8
7-amino-1,3-naphthalenedisulfonic acid 9.6
8S-HETE 9.4
Boc-Asn 9.1
6-Methylpurine 8.9
Gallocyanin 8.9
methyl 4-aminobenzoate 8.8
Cyclotene 8.8
1,5-isoquinolinediol 8.8
Guanidine thiocyanate 8.8
6-Methylpurine 8.6
7-Methylguanosine 8.6
3-hydroxy-2-pyrazinecarboxamide 8.3
MDAB 8.3
Pyronine G 8.2
Camphorquinone 7.8
2-AB 7.6
4-Thiouridine 7.5
Mescaline 7.5
AMAC 7.5
Bicine 7.2
C6H12O6 7.1
Poly C 6.8
selenous acid 6.8
selenous acid 6.8
selenous acid 6.8
selenous acid 6.8
3'-AMP 6.7
selenous acid 6.7
4-fluorophenylalanine 6.7
Diethyl pyrocarbonate 6.7
S-15 6.6
2-aminobenzoic acid 6.6
2-aminobenzoic acid 6.6
2-aminobenzamide 6.5
S-sulfocysteine 6.5
Diadenosine tetraphosphate 6.5
Chondroitin sulfate A 6.4
Picric acid 6.4
Thiostrepton 6.4
Retinyl acetate 6.3
ECP 6.2
3-quinolinecarboxylic acid 6.2
ECP 6.2
ECP 6.2
Pseudouridine 6.1
Coomassie Brilliant Blue G 6.1
Atractyloside 6.1
Benfluron 5.9
7-methylguanosine 5.9
glucosamine-6-phosphate 5.9
Amido black 5.9
mercaptopyruvate 5.9
Cyd 5.9
3-aminobenzoic acid 5.8
R 1881 5.8
40S 5.7
Cepharanthine 5.7
2-ethoxyethanol 5.6
PIN 5.6
2-methyl-2,4-pentanediol 5.6
Sodium deoxycholate 5.6
Sialic acid 5.6
UMP 5.5
Sodium acetate 5.5
Ethionine 5.5
Oil Red 5.5
GAR 5.5
2-oxoadipate 5.5
2-ethoxyethanol 5.4
CMP 5.4
Allantoin 5.4
Allantoin 5.4
uridine 5.3
DEAE 5.3
more...