Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.27.4 (ribonuclease)
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Human Gene/Protein
RNASE4 protein 12.2
truncated lactoferrin 12.2
HEPN1 12.2
FLJ35220 protein 12.2
RNase k6 11.4
modulator recognition factor 1 11.2
SPINT4 11.2
cystatin pseudogene 11.2
beta1,4GalNAc-T 11.2
RNase kappa 11.2
ribonuclease 4 10.9
RNH1 10.8
PARN 10.7
C20orf72 10.6
Eosinophil-derived neurotoxin 10.6
EXOSC2 10.6
ALDR1 10.6
TM4SF1 protein 10.6
ZFY protein 10.6
SUPV3L1 10.5
RNase 4 10.4
RNase 8 10.2
T-complex protein 1 subunit beta 10.2
gene trap ankyrin repeat 10.2
CDKN2AIPNL 10.2
Kcn1 10.2
ERN2 10.2
RNASET2 10.1
Ribonuclease T2 10.1
EDN 10.0
ribonuclease A 10.0
eosinophil-derived neurotoxin 9.9
endothelial-overexpressed lipopolysaccharide-associated factor 1 9.9
Mtr3p 9.9
placental protein 11 9.6
XPMC2 9.6
EIF4E2 9.6
tubulin alpha 6 9.6
PABP4 9.6
N-acetylneuraminate pyruvate lyase 9.6
more...
Disease
adult pineoblastoma 12.2
Molybdenum deficiency 10.6
HBN1 10.2
Hepatic hemosiderosis 9.9
ovarian mixed germ cell tumor 9.1
Pineoblastoma 8.4
IGHD II 8.2
monosomy 8p 8.1
Porencephaly 7.8
HPC1 7.2
Lassa virus infection 7.1
Ichthyosis vulgaris 7.0
KNS 7.0
Perlman syndrome 6.9
latent virus infection 6.8
PPR1 6.8
mouse leukemia P388 6.6
Pancreatic necrosis 6.6
bacterial dysentery 6.5
Spring viremia of carp 6.5
nRNA 6.4
CMCT 6.3
Giant cell myocarditis 6.3
trichomonal vaginitis 6.3
white muscle disease 6.2
SAMS 6.0
Visna 6.0
mixed connective tissue disease 5.9
PIN 5.9
pinguecula 5.8
FAB M1 5.8
Stretches 5.8
Acute necrotizing pancreatitis 5.7
ARH 5.6
alcoholic myopathy 5.5
Chronic progressive external ophthalmoplegia 5.4
Fungal keratitis 5.2
RPC 5.2
Turcot syndrome 5.1
Hypereosinophilic syndrome 5.1
more...
Symptom
RNA marker 7.6
female puberty 5.3
POA 4.2
autodigestion 3.9
Halo 3.4
starvation 3.0
muscle rigidity 2.2
physical appearance 1.7
hyperoxia 1.5
masculinization 0.9
Ill 0.8
HSA 0.7
collapse 0.4
arthralgia 0.4
dysarthria 0.4
chills 0.2
exhaustion 0.1
acidity -0.1
ataxia -0.1
cachexia -0.2
hypotonia -0.3
agitation -0.3
flushing -0.4
weakness -1.4
stigma -1.5
anorexia -1.5
hypothermia -1.8
tremor -1.9
respiratory distress -2.0
discomfort -2.2
discomfort -2.3
fatigue -2.4
seizures -2.5
dyspnea -2.5
diarrhea -2.6
anesthesia -2.9
pain -3.2
Drug
Onconase 10.9
Mitogillin 10.9
6-Methylpurine 8.9
7-Methylguanosine 8.6
Pronase 7.3
Bicine 7.2
Peanut oil 7.1
Arlacel 6.9
Gly-Tyr-Gly 6.8
Astragali radix 6.6
Pregnyl 6.2
Sodium acetate 5.5
Guanidine 5.4
Guanidine 5.4
Trapidil 5.4
Cytidine 5.4
TPV 5.4
KGF 5.3
Protamine sulfate 5.3
Vanilla 5.1
Eptifibatide 5.1
RBT 5.1
Bentonite 4.7
Papain 4.7
Asn 4.6
R-gene 4.6
Lupron 4.6
FCV 4.4
Kaolin 4.3
Sodium alginate 4.3
Lactase 4.1
CED 4.1
R1881 3.9
Doyle 3.6
-deoxyadenosine 3.5
Aminoguanidine 3.5
Gel 3.5
Fraction 3.5
anti-RSV 3.4
ISP 3.3
more...
Enzyme
ribonuclease 12.2
ribonuclease 12.2
yeast ribonuclease 11.6
RNase 10.9
RNase 10.8
EC 2.1.1.31 10.6
ribonuclease alpha 10.4
EC 2.1.1.32 10.2
tRNA sulfurtransferase 9.9
deoxyribonuclease 9.7
deoxyribonuclease 9.6
poly(A)-specific ribonuclease 9.4
RNase T1 9.3
alpha-sarcin 9.1
RNase D 8.8
exoribonuclease 8.6
oligoribonuclease 8.6
RNase M5 8.4
glutathione-insulin transhydrogenase 8.4
polynucleotide phosphorylase 8.2
isochorismatase 8.0
protein disulfide-isomerase 7.9
D-galactose dehydrogenase 7.8
3'-phosphatase 7.8
RNase III 7.8
RNase PH 7.8
cytochrome b6/f complex 7.6
venom phosphodiesterase 7.6
EC 2.3.1.29 7.5
DNase 7.5
3'-exonuclease 7.5
8-amino-7-oxononanoate synthase 7.5
poly(A)-specific ribonuclease 7.3
protein methylase II 7.3
DNase II 7.1
methionine decarboxylase 7.1
RNase H 7.1
coagulation factor XIa 7.0
thiogalactoside transacetylase 7.0
tRNase Z 6.8
more...
Compound
Diguanosine triphosphate 12.2
5-aminotryptophan 12.2
p-Aminobenzoylglutamic acid 11.2
3-Aminoquinoline 11.2
Pyridine borane 10.6
3'-UMP 9.8
7-amino-1,3-naphthalenedisulfonic acid 9.6
8S-HETE 9.4
Boc-Asn 9.1
6-Methylpurine 8.9
Gallocyanin 8.9
Cyclotene 8.8
Guanidine thiocyanate 8.8
methyl 4-aminobenzoate 8.8
1,5-isoquinolinediol 8.8
6-Methylpurine 8.6
7-Methylguanosine 8.6
3-hydroxy-2-pyrazinecarboxamide 8.3
MDAB 8.3
Pyronine G 8.2
Camphorquinone 7.8
2-AB 7.6
4-Thiouridine 7.5
Mescaline 7.5
AMAC 7.5
Bicine 7.2
C6H12O6 7.1
Poly C 6.8
selenous acid 6.8
selenous acid 6.8
selenous acid 6.8
selenous acid 6.8
3'-AMP 6.7
selenous acid 6.7
4-fluorophenylalanine 6.7
Diethyl pyrocarbonate 6.7
S-15 6.6
2-aminobenzoic acid 6.6
2-aminobenzoic acid 6.6
2-aminobenzamide 6.5
more...