Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.27.4 (ribonuclease)
6,621 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 629
RNase 609
Sep 467
ribonuclease A 447
RNase A 266
deoxyribonuclease 250
tRNA 208
lysozyme 205
polypeptide 173
Ribonuclease 150
glycoprotein 148
NMR 123
insulin 111
serum albumin 105
ATP 104
cytokine 104
dimeric 103
angiogenin 103
ribonucleoprotein 98
endonuclease 91
endoplasmic reticulum 89
SDS 87
interferon 77
Dicer 75
Poly 72
albumin 72
fused 68
eosinophil-derived neurotoxin 67
Gen 66
RNase H 65
RNase III 65
eosinophil cationic protein 65
alkaline phosphatase 63
RNase E 63
amylase 60
vitronectin 60
chymotrypsin 57
lectin 57
thymus 54
microsomal 53
lipase 52
PRI 52
membrane-bound 52
Pseudomonas 52
PARN 50
collagen 50
AMP 50
phosphatase 47
acid phosphatase 45
peroxidase 45
Met 43
hemoglobin 42
phosphodiesterase 41
IL-6 40
Angiogenin 40
tumor necrosis factor 39
cytochrome c 39
myoglobin 39
polynucleotide phosphorylase 39
neuraminidase 37
RNA polymerase II 37
RNase L 35
transferrin 35
lipopolysaccharide 35
estrogen receptor 31
TOF 30
IGF-I 30
DNA polymerase 30
GTP 29
beta-actin 28
IL-1 27
ATPase 27
trypsin inhibitor 27
histone 26
growth hormone 26
TNF-alpha 26
DNase 26
RNA polymerase I 25
RNP 25
dilute 25
ADP 25
catalase 25
IFN-gamma 24
ribosomal protein 24
EDN 23
helicase 23
beta-glucuronidase 23
interferon-gamma 23
proteasome 22
p53 22
brain-derived neurotrophic factor 22
ESI 22
IL-10 22
Sp1 22
ubiquitin 22
alternatively spliced 22
reductase 22
prolactin 21
IGF-II 21
GMP 21
cytochrome 21
ACTH 21
MRP 20
gut 20
lymphoid 20
UTR 20
Pol 20
erythroid 20
alpha-amylase 20
Cytokine 20
epidermal growth factor receptor 20
interleukin-6 19
RNase H1 19
hyaluronidase 19
FSH 19
androgen receptor 19
RNA-binding protein 19
renin 18
nerve growth factor 18
insulin-like growth factor-I 18
fibronectin 18
angiotensin II 18
TGF-beta 18
chemokine 18
Eosinophil-derived neurotoxin 18
threonine 17
membrane protein 17
CD4 17
trypsinogen 17
RACE 17
DNase I 17
GH receptor 17
thyroid hormone 17
GSH 17
PIN 17
casein 17
ALA 17
protein disulfide isomerase 16
IRE1 16
genomic clone 16
phospholipase A2 16
leptin 16
thioredoxin 16
lactoferrin 16
glucosamine 16
housekeeping 16
oxytocin 16
insulin-like growth factor I 15
fibrinogen 15
caspase-3 15
beta 1 15
glucagon 15
DICER1 15
tyrosine kinase 15
collagenase 15
CA1 15
ferritin 15
IFN 15
RNA helicase 14
epidermal growth factor 14
more...
Disease
cancer 274
tumor 255
SDS 87
HIV 78
carcinoma 64
leukemia 54
hepatocellular carcinoma 50
breast cancer 50
cold 48
immunodeficiency 47
diabetes 38
virus infection 35
uterus 33
tuberculosis 32
Mycobacterium 32
plaque 32
influenza 31
melanoma 29
systemic lupus erythematosus 27
pancreatic cancer 25
adenocarcinoma 25
tumor growth 24
neuroblastoma 23
hypertension 23
Alzheimer's disease 22
tumorigenesis 22
multiple myeloma 20
pancreatitis 20
prostate cancer 19
stomatitis 18
MCF 18
GSH 17
mixed connective tissue disease 16
acute pancreatitis 16
PIN 16
PIN 16
amyotrophic lateral sclerosis 15
epididymis 15
malignant mesothelioma 14
mole 14
infectious diseases 14
rheumatoid arthritis 14
SEM 14
Infection 13
ovarian cancer 13
Mycoplasma 13
asthma 13
chronic pancreatitis 13
sarcoma 13
metastases 13
epithelial ovarian cancer 13
mole 13
depression 12
carcinogenesis 12
cystic fibrosis 12
obesity 12
erythroleukemia 12
ischemia 12
AIDS 12
atherosclerosis 11
lung cancer 11
vaccinia 11
seminal vesicles 11
Rous sarcoma 11
acute myeloid leukemia 11
hepatitis C 11
hepatitis B 11
malnutrition 10
lymphoma 10
tumor progression 10
renal disease 10
hepatitis 10
gastric cancer 9
stroke 9
cytomegalovirus 9
dehydration 9
cholera 9
renal failure 9
fits 9
colorectal cancer 9
Parkinson's disease 9
bladder cancer 8
Schmidt 8
Klebsiella 8
pneumonia 8
heart failure 8
tumor angiogenesis 8
herpes simplex 8
scleroderma 8
SCID 8
glioma 8
dysplasia 8
MIP 8
polymyositis 8
SARS 7
lung carcinoma 7
dementia 7
cirrhosis 7
arthritis 7
chronic myeloid leukemia 7
PSS 7
chronic lymphocytic leukemia 7
anemia 7
squamous cell carcinoma 7
mesothelioma 7
Yersinia 7
Epstein 6
adenoma 6
diabetic nephropathy 6
colon cancer 6
Dissociation 6
Leukemia 6
encephalomyelitis 6
mammary tumor 6
Raynaud 6
NAME 6
pulmonary hypertension 6
multiple sclerosis 6
Hymenolepis 6
Schistosoma mansoni 6
osteosarcoma 6
sepsis 6
chondrodysplasia 6
acute promyelocytic leukemia 6
proteinuria 6
myeloid leukemia 6
Proteus 6
embryonal carcinoma 6
Hodgkin's disease 6
sepsis 6
pheochromocytoma 6
Pituitary 6
liver cancer 6
myeloblastosis 6
goiter 6
pertussis 5
viremia 5
eosinophilia 5
neuropathy 5
NS3 5
nephritis 5
PCC 5
West 5
myocarditis 5
cornea 5
neoplastic transformation 5
Moore 5
myocardial infarction 5
viral diarrhea 5
ATM 5
APC 5
encephalitis 5
chronic lymphocytic leukemia 5
glioblastoma 5
glomerulonephritis 5
cognitive impairment 5
Newcastle disease 5
Burkitt's lymphoma 5
chronic renal failure 5
lupus 5
more...
Symptom
starvation 41
collapse 8
pain 6
Ill 4
anesthesia 3
exhaustion 3
hyperoxia 3
ataxia 3
seizures 3
acidity 3
weakness 3
POA 2
agitation 2
diarrhea 2
arthralgia 2
fatigue 2
stigma 1
masculinization 1
female puberty 1
flushing 1
RNA marker 1
discomfort 1
respiratory distress 1
dysarthria 1
hypotonia 1
chills 1
dyspnea 1
cachexia 1
hypothermia 1
physical appearance 1
anorexia 1
Halo 1
discomfort 1
autodigestion 1
muscle rigidity 1
tremor 1
HSA 1
Drug
lysine 113
Asn 61
Onconase 44
Pronase 42
Gel 35
IFN-gamma 24
Dermatol 20
DNase I 17
Biopolymers 16
EE2 16
CSF 14
IL-2 12
MAP 11
NADH 10
Cardiovasc 8
lactose 8
PTH 8
Albumin 6
Fraction 6
-deoxyadenosine 5
Silica 5
Ethanol 5
Nephron 5
ETA 4
Leaf 4
KGF 4
Retinoic acid 4
CaCl2 4
Forskolin 4
Glutathione 4
ROS 4
CaCl2 4
G-CSF 4
p75 4
ICI 4
CDP 4
ENT 4
CaCl2 4
IFN-beta 4
Growth hormone 3
Growth hormone 3
ABC 3
Guanidine 3
ADR 3
Papain 3
Alanine 3
ascorbate 3
Guanidine 3
Fragment 3
Fluorescein 2
Gelatin 2
DHT 2
ADM 2
Indomethacin 2
VCR 2
DHT 2
Dial 2
Spectrum 2
Bifidobacterium 2
Mitogillin 2
Fluorescein 2
DM1 2
Cytidine 2
Glucagon 2
NAG 2
Capsicum 2
Angiotensin II 2
Spectrum 2
CED 2
G418 2
Nephron 2
R1881 2
DMI 2
Kenyan 2
NaI 1
Ouabain 1
Prednisolone 1
Fructose 1
Activin 1
Trapidil 1
Protamine sulfate 1
caffeine 1
Astragali radix 1
Rosiglitazone 1
Arlacel 1
CPM 1
Hypaque 1
Paraffin 1
IL-1ra 1
anti-RSV 1
Luteinizing 1
Eptifibatide 1
FCV 1
Heme 1
nitroglycerin 1
MgSO4 1
Cetuximab 1
NaI 1
Troglitazone 1
CoCl2 1
CoCl2 1
Glide 1
ISP 1
niacin 1
ROC 1
Oxaliplatin 1
CTA 1
AraC 1
pyridoxal phosphate 1
Herceptin 1
VCR 1
ZnCl2 1
citric acid 1
CTC 1
Aminoguanidine 1
Lactase 1
Estrogens 1
Adriamycin 1
TPV 1
Kaolin 1
Bentonite 1
L-tyrosine 1
NaI 1
Gly-Tyr-Gly 1
Serum albumin 1
Doyle 1
ampicillin 1
ZnCl2 1
Peanut oil 1
R-gene 1
SiO2 1
DEX 1
IPM 1
Glycerol 1
Aprotinin 1
Hypaque 1
Monensin 1
Arsenic trioxide 1
Vanilla 1
Sodium acetate 1
ZnO 1
TES 1
AGG 1
RBT 1
DFP 1
Glutamic acid 1
Bicine 1
TAT 1
CAM 1
Methylprednisolone 1
7-Methylguanosine 1
Lupron 1
Thyroglobulin 1
Lactose 1
Nitric Oxide 1
PCP 1
NaI 1
Histamine 1
Pregnyl 1
6-Methylpurine 1
more...
Enzyme
ribonuclease 6621
RNase 6595
RNase 6593
ribonuclease 6589
DNase 289
deoxyribonuclease 249
deoxyribonuclease 248
trypsin 220
lysozyme 207
RNase T1 165
RNA polymerase 142
reverse transcriptase 126
endonuclease 91
alkaline phosphatase 76
RNase H 76
chymotrypsin 66
exoribonuclease 61
peroxidase 61
acid phosphatase 59
lipase 53
protein kinase 51
luciferase 51
RNase III 47
phosphodiesterase 46
polynucleotide phosphorylase 45
ATPase 43
neuraminidase 42
DNA polymerase 40
transcriptase 38
pepsin 36
S1 nuclease 33
ERK 33
catalase 32
RNase P 28
proteinase K 27
PNGase F 26
proteasome 25
alpha-sarcin 25
subtilisin 24
phospholipase C 23
beta-glucuronidase 22
phospholipase A2 21
protein kinase C 20
alpha-amylase 20
micrococcal nuclease 20
hyaluronidase 20
hyaluronidase 19
papain 18
venom phosphodiesterase 18
renin 18
ricin 18
collagenase 17
mitogen-activated protein kinase 17
superoxide dismutase 17
beta-galactosidase 16
lactate dehydrogenase 16
glutathione S-transferase 16
glyceraldehyde-3-phosphate dehydrogenase 16
3'-exonuclease 15
gamma-glutamyl transpeptidase 15
glyceraldehyde-3-phosphate dehydrogenase 14
caspase-3 14
chloramphenicol acetyltransferase 14
thrombin 13
purine nucleoside phosphorylase 12
RNA ligase 12
DNase II 12
elastase 12
aldolase 12
ACS 12
thermolysin 11
glyceraldehyde-3-phosphate dehydrogenase 11
5'-nucleotidase 11
poly(A)-specific ribonuclease 11
endoglycosidase H 10
glyceraldehyde-3-phosphate dehydrogenase 10
adenylate cyclase 10
NO synthase 10
P-glycoprotein 10
alpha-glucosidase 10
glyceraldehyde-3-phosphate dehydrogenase 10
diaphorase 9
malate dehydrogenase 9
focal adhesion kinase 9
enolase 9
beta-lactamase 9
caspase-8 9
caspase-9 9
tissue plasminogen activator 9
calcineurin 9
RNase PH 9
glucose-6-phosphate dehydrogenase 8
polynucleotide kinase 8
cathepsin D 8
urease 8
invertase 8
poly(A) polymerase 8
3'-phosphatase 8
protein disulfide-isomerase 8
MIP 8
tyrosine hydroxylase 8
urease 8
DNA ligase 7
adenosine deaminase 7
adenosine deaminase 7
DNA ligase 7
CPR 7
aspartate aminotransferase 7
deaminase 7
ACE 7
acetylcholinesterase 7
nucleotidase 7
topoisomerase 6
topoisomerase 6
CD10 6
hexosaminidase 6
glutathione peroxidase 6
lipoprotein lipase 6
phosphofructokinase 6
alpha-mannosidase 6
RNase D 6
ornithine decarboxylase 5
PARP 5
kallikrein 5
carbonic anhydrase 5
HSD 5
succinate dehydrogenase 5
phospholipase D 5
complex I 5
guanylate cyclase 5
carboxypeptidase A 5
cathepsin C 5
thymidine kinase 5
MEK 5
HIV-1 protease 5
alcohol dehydrogenase 5
dihydrofolate reductase 5
glutathione-insulin transhydrogenase 5
ATP synthase 5
hexokinase 5
chitinase 5
glutamate dehydrogenase 4
chymosin 4
AMPK 4
glutamate dehydrogenase 4
glutamate dehydrogenase 4
DNA methyltransferase 4
cdc2 4
thymidylate synthase 4
alanyl-tRNA synthetase 4
valyl-tRNA synthetase 4
pyruvate kinase 4
transglutaminase 4
PDE 4
citrate synthase 4
xanthine oxidase 4
beta-glucosidase 4
phosphorylase 4
CD13 4
sialidase 4
more...
Compound
DNA 816
Dec 504
phosphate 265
sodium 256
water 215
sulfate 188
lysine 176
His 170
Clin 161
hydrogen 142
salt 142
leucine 125
DEAE 124
alanine 121
arginine 119
calcium 115
urea 113
uridine 107
ATP 104
glucose 103
galactose 100
tyrosine 99
cysteine 97
SDS 96
ammonium 93
methionine 91
acetate 87
Mg2+ 86
Asp 85
oxygen 82
Phe 82
EDTA 72
EDTA 72
zinc 69
phenol 66
pyrimidine 65
pyrimidine 65
threonine 60
ethanol 53
AMP 52
bromide 52
tryptophan 52
cAMP 52
serine 51
Gly 50
proline 50
nitrogen 49
manganese 49
tryptophan 48
GMP 47
tryptophan 47
tryptophan 47
potassium 44
GlcNAc 41
guanidine 40
acrylamide 38
iron 36
copper 36
asparagine 35
Triton X-100 35
PEG 34
Guo 33
HCl 31
40S 31
TCA 31
NH2 31
TOF 30
GTP 30
Ile 29
iodine 28
nitric oxide 27
chloroform 25
retinoic acid 25
ADP 25
ADP 25
aspartic acid 25
methanol 25
glycerol 25
ADP 25
glutamic acid 25
aspartic acid 24
aspartic acid 24
aspartic acid 24
adenylate 23
formamide 22
GSH 21
GSH 21
PEG 20
Insulin 20
glutamine 19
phosphorus 19
creatinine 19
MgCl2 19
glutamate 18
CMP 18
silver 18
valine 18
ACTH 18
perchloric acid 18
formaldehyde 18
Tris 18
acetone 17
UTP 16
PIN 16
hydroxide 16
Estradiol 16
aldosterone 16
Sucrose 16
Tris 16
NAD 15
acetic acid 15
nitrate 15
formaldehyde 15
Optimal 14
cobalt 14
cadmium 14
cGMP 14
COS 14
CMP 13
PAM 13
ACS 13
vitamin D 13
PAM 13
Adenosine 12
ACS 12
GSSG 12
TNF 11
isopropanol 11
CTP 11
UMP 11
hexose 11
ADP-ribose 11
Sialic acid 11
Neu5Ac 11
Progesterone 11
Trypsin 11
Dexamethasone 11
2-mercaptoethanol 11
acridine 11
NADH 10
nickel 10
NAD 10
Triton 10
sodium chloride 9
salicylic acid 9
ammonia 9
TSH 9
H2O2 9
NADPH 9
MDA 9
CO2 9
NADPH 9
MIA 8
Testosterone 8
hexose 8
Heparin 8
Inositol 8
Thyroid 8
hexose 8
mercury 8
more...