Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.27.3 (RNase T1)
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Human Gene/Protein
Placental ribonuclease inhibitor 13.1
RNase 8 12.7
ribonuclease T2 12.2
hPop5 11.5
Parvulin 11.3
Acid carboxypeptidase 11.2
RNase E 10.9
RNA adenosine deaminase 10.8
Ribonuclease 10.4
Ribosomal protein L11 10.3
RNase A 10.1
MTPAP 10.0
PNPase 9.9
B47 9.9
CEP3 9.7
CBF-A 9.6
PRP2 9.5
pol protein 9.5
2'-phosphotransferase 9.4
POMP 9.3
MSY2 9.3
FKBP22 9.2
peptidylprolyl cis-trans isomerase 9.2
DnaJ-like protein 9.1
TAD2 9.0
parvulin 9.0
Peptidylglycine alpha-amidating monooxygenase 9.0
GNN 9.0
PRB1 8.9
ribonuclease A 8.8
PRP8 8.7
deoxynucleotidyltransferase 8.6
AKV 8.6
small acidic protein 8.6
RNase 8.6
Envelope glycoprotein 8.6
GMP 8.5
PRPF8 8.5
prolyl isomerase 8.5
HN1 8.5
CHMP4B 8.4
PRNT 8.3
NAK 8.3
Cyclophilin 8.3
FKBP 8.3
PRI 8.3
CACC 8.3
C151 8.2
TCF21 8.1
RNA-directed DNA polymerase 8.1
COB 8.1
G18 8.1
MCPIP1 8.0
DTD 7.9
TyrRS 7.9
DB1 7.8
MAV 7.8
RNase III 7.8
SP6 7.8
tRNase Z 7.8
hnRNP A2 7.7
hnRNP L 7.7
PPIase 7.7
HMT 7.7
protamine 2 7.6
polynucleotide phosphorylase 7.6
protamine 1 7.6
G30 7.6
ribosomal protein L11 7.6
peptidyl prolyl cis-trans isomerase 7.6
RNase H 7.6
PCBP2 7.6
peptidyl-prolyl cis-trans isomerase 7.5
exonuclease 1 7.5
3' exoribonuclease 7.5
p63) 7.4
K25 7.4
NNH 7.4
G72 7.4
SAT1 7.4
A33 7.4
SPINT2 7.3
P39 7.3
GBL 7.3
FDC 7.3
DAI 7.2
RNA helicase A 7.2
methionyl-tRNA synthetase 7.2
MMP-11 7.2
p68 kinase 7.2
D40 7.2
valyl-tRNA synthetase 7.1
SIII 7.1
G16 7.1
P56 7.1
NSP3 7.0
SL1 7.0
RPC 7.0
snRNP 7.0
mitochondrial RNA polymerase 7.0
L11 7.0
BEST 6.9
L30 6.9
hnRNP 6.9
RFI 6.9
MC1 6.8
L17 6.8
malin 6.8
DBT 6.8
IRP2 6.7
TFIIIC 6.7
IRP1 6.7
DMS 6.6
G20 6.6
S14 6.6
RNP 6.6
L12 6.5
SIL 6.5
S19 6.5
RNase L 6.5
NADH-ubiquinone oxidoreductase 6.5
tRNA 6.4
GCG 6.4
FOLR1 6.4
p30 6.4
ATG8 6.4
TFIIIB 6.4
cyclophilin 6.4
P65 6.3
La protein 6.3
G13 6.3
transforming protein 6.3
amino acid permease 6.3
L15 6.3
SM3 6.3
eosinophil-derived neurotoxin 6.3
peroxiredoxin 6 6.3
SPP 6.3
MS2 6.3
HN2 6.2
RIS 6.2
proton-coupled folate transporter 6.2
S10 6.2
NPL 6.2
TH protein 6.1
P34 6.1
E.coli 6.1
RNA polymerase I 6.1
Cam 6.1
TL1A 6.1
alpha globin 6.1
acetaldehyde dehydrogenase 6.0
inhibitor 2 6.0
MSV 6.0
p68 6.0
UBC 6.0
beta-globin 6.0
CCA 6.0
CRD 6.0
elongation factor Tu 6.0
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Disease
CMCT 11.6
Trivittatus 11.2
AKV 8.8
Visna 8.4
avian sarcoma 8.4
Avian infectious bronchitis 8.4
TD1 8.3
NNH 7.9
Murray Valley encephalitis 7.7
DTD 7.6
Rous sarcoma 7.3
FDC 7.2
myeloblastosis 7.0
RPC 7.0
X-linked lymphoproliferative syndrome 7.0
DMS 6.7
mouth disease 6.4
Schmidt 6.3
LYP 6.3
Venezuelan equine encephalitis 6.2
osteopetrosis 6.0
lymphosarcoma 6.0
Vesicular stomatitis 6.0
RCM 5.9
Ross River 5.8
Fox 5.7
CAA 5.7
Friend leukemia 5.7
avian leukosis 5.7
PHP 5.6
western equine encephalomyelitis 5.6
EMC 5.6
CAA 5.3
WSN 5.2
WSN 5.2
stuttering 5.0
FMD 5.0
hemangioblastoma 4.8
Gilbert 4.8
Foot-and-mouth disease 4.7
stomatitis 4.6
sarcoma 4.5
acute leukemia 4.3
neuromuscular disorder 4.3
coxsackievirus 4.2
DSS 4.2
FMD 4.2
bronchitis 4.0
CSA 3.9
DSS 3.9
bronchitis 3.9
PAM 3.8
AGA 3.8
Sarcoma 3.8
Sarcoma 3.8
erythroleukemia 3.7
osteoma 3.6
vaccinia 3.6
encephalomyelitis 3.6
T-cell acute lymphoblastic leukemia 3.4
SLE 3.4
PDE 3.3
human papilloma virus 3.3
human papilloma virus 3.3
leukemia 3.2
EIA 3.2
AAA 3.1
lymphocytic choriomeningitis 3.1
Adenovirus 3.1
hepatitis 3.0
polio 2.9
fragile X syndrome 2.9
lymphoblastic leukemia 2.7
SDS 2.6
DM1 2.6
thymoma 2.5
MAS 2.5
conjunctivitis 2.4
dengue 2.4
retinitis pigmentosa 2.3
CAM 2.2
mimicry 2.2
PCC 2.1
rhabdomyosarcoma 2.1
mammary tumor 2.0
hepatitis A 2.0
PDB 1.9
mesothelioma 1.9
pheochromocytoma 1.8
bone disease 1.8
solid tumor 1.8
fits 1.7
aspergillosis 1.7
lung carcinoma 1.7
avian influenza 1.7
Proteus 1.7
Cryptococcus neoformans 1.7
WT1 1.6
abdominal aortic aneurysm 1.6
glioblastoma multiforme 1.5
influenza 1.4
Yersinia 1.4
plague 1.4
cold 1.3
thalassemia 1.3
Conn 1.3
plaque 1.3
gastroenteritis 1.2
acute myeloid leukemia 1.1
immunodeficiency 1.1
brain tumor 1.1
virus infection 1.1
Brown 1.1
ATM 1.0
MCF 0.9
Mycoplasma 0.8
Haemophilus 0.8
hyperlipidemia 0.7
HIV 0.6
anemia 0.6
mole 0.5
GSH 0.4
tumor growth 0.4
primary tumor 0.4
cholera 0.3
vasculitis 0.3
pancreatic cancer 0.3
hypoglycemia 0.3
mole 0.3
systemic lupus erythematosus 0.2
cervical cancer 0.2
hepatocellular carcinoma 0.1
coronary heart disease 0.1
Epstein 0.1
lymphoma 0.1
tumor 0.0
Mycobacterium -0.0
colorectal cancer -0.0
neuroblastoma -0.1
colon cancer -0.2
glioma -0.3
hepatitis C -0.4
adenocarcinoma -0.4
melanoma -0.4
tuberculosis -0.6
squamous cell carcinoma -0.8
carcinoma -1.0
AIDS -1.2
cancer -1.2
atherosclerosis -1.6
ischemia -1.8
Alzheimer's disease -2.1
obesity -2.3
diabetes -3.4
Symptom
starvation 3.1
splenomegaly 1.4
collapse 0.9
Drug
Diastase 10.6
8-Azaguanine 10.0
Trifluoroethanol 8.4
Onconase 7.9
Lead acetate 7.4
Pyridoxal 6.6
Guanidine 6.3
Guanidine 6.3
SPP 6.1
CSI 5.8
Singular 5.7
Pronase 5.3
Asn 5.1
Fragment 5.1
Ranitidine 5.0
DNase I 5.0
-deoxyadenosine 4.6
Vitamin B 4.4
Alanine 4.2
Gleevec 4.2
DM1 4.0
Gel 3.8
Biopolymers 3.6
G418 3.5
CDP 3.5
TAT 3.4
Imatinib 3.4
ETS 3.3
Fluorescein 3.3
Fluorescein 2.8
lysine 2.5
Mutagen 2.1
citric acid 1.4
lactose 0.6
Nephron 0.5
Enzyme
RNase T1 14.7
EC 2.1.1.34 12.3
RNase M5 10.9
alpha-sarcin 10.6
methionyl-tRNA formyltransferase 10.2
ribonuclease 9.3
ribonuclease 9.2
polynucleotide kinase 9.2
RNase 9.0
RNase 8.8
RNA ligase 8.7
Tpt1 8.7
RNase D 8.6
RNase PH 8.6
RNase III 8.6
cytochrome b6/f complex 8.5
polynucleotide phosphorylase 8.5
carboxyl proteinase 8.4
exoribonuclease 7.7
S1 nuclease 7.6
tRNase Z 7.6
RNase H 7.6
endonuclease V 7.5
venom phosphodiesterase 7.4
peptidyl-prolyl cis-trans isomerase 7.4
protein disulfide-isomerase 7.3
RNase P 7.3
methionyl-tRNA synthetase 7.1
valyl-tRNA synthetase 7.1
mannosidase I 7.0
purine nucleoside phosphorylase 6.8
lysyl endopeptidase 6.7
poly(A) polymerase 6.3
chitosanase 6.2
nucleotide pyrophosphatase 6.1
3'-exonuclease 6.0
proteinase K 5.8
PDH 5.3
micrococcal nuclease 5.2
rhodanese 5.1
RNA polymerase 5.1
endonuclease 5.1
PAT 4.9
caspase-7 4.9
p100 4.9
caspase-7 4.8
enolase 4.8
cytidine deaminase 4.7
alcohol dehydrogenase 4.5
carboxypeptidase Y 4.3
chymotrypsin 4.2
DNA ligase 4.2
DNA ligase 4.2
transpeptidase 4.1
deoxyribonuclease 4.1
deoxyribonuclease 4.1
DNase 4.1
5'-nucleotidase 4.0
ricin 4.0
phosphoenolpyruvate carboxylase 3.9
aldolase 3.9
PAM 3.8
thermolysin 3.8
glucoamylase 3.6
DNA polymerase 3.6
chaperonin 3.6
phosphoglycerate kinase 3.6
glyceraldehyde-3-phosphate dehydrogenase 3.6
glyceraldehyde-3-phosphate dehydrogenase 3.6
glyceraldehyde-3-phosphate dehydrogenase 3.5
lysozyme 3.4
TAT 3.4
histidine kinase 3.4
reverse transcriptase 3.4
SPC 3.3
alkaline phosphatase 3.3
asparaginase 3.3
pyruvate dehydrogenase 3.2
firefly luciferase 3.2
glyceraldehyde-3-phosphate dehydrogenase 3.2
dihydrofolate reductase 3.2
trypsin 3.1
transcriptase 3.0
furin 3.0
glyceraldehyde-3-phosphate dehydrogenase 3.0
pyruvate dehydrogenase 2.9
pyruvate dehydrogenase 2.9
PDE 2.8
neutrophil elastase 2.7
phosphoenolpyruvate carboxykinase 2.6
phosphoenolpyruvate carboxykinase 2.6
subtilisin 2.6
phosphoenolpyruvate carboxykinase 2.5
laccase 2.5
invertase 2.4
adenosine deaminase 2.3
adenosine deaminase 2.3
CPR 2.3
demethylase 2.2
diaphorase 2.1
phosphodiesterase 2.1
ornithine decarboxylase 2.0
aldehyde dehydrogenase 2.0
papain 2.0
complex I 1.5
luciferase 1.4
adenylate cyclase 1.4
acid phosphatase 1.0
protein kinase 0.9
phospholipase A2 0.9
beta-galactosidase 0.8
tyrosine hydroxylase 0.8
ACE 0.5
lipase 0.5
ATPase -0.3
caspase-3 -0.5
ERK -0.9
mitogen-activated protein kinase -0.9
protein kinase C -0.9
superoxide dismutase -1.2
peroxidase -1.3
ACS -1.6
Compound
Z-Gly-Pro-Leu-Gly-Pro 11.9
p-Terphenyl 11.5
GIX 11.1
Dihydrouridine 10.3
POPOP 9.8
2-methyl-2,4-pentanediol 8.6
Pseudouridine 8.5
Z-Gly-Pro 8.4
Diethyl pyrocarbonate 8.1
SC-1 8.1
SC-1 8.1
7-methylguanosine 8.0
GMP 8.0
BDH 7.9
AG-3 7.7
NFS 7.7
PIPES 7.5
PIPES 7.5
PIPES 7.5
DMS 7.3
3'-AMP 7.2
C56 7.1
Sarcosine 6.8
DBT 6.8
Pentamidine 6.7
40S 6.7
Azan 6.7
Pyridoxal 6.6
Trimethylamine N-oxide 6.5
methylguanosine 6.5
fMet 6.5
Dithiothreitol 6.2
UMP 6.1
Dithiothreitol 6.0
HN2 6.0
CMP 6.0
G20 6.0
TAR 5.9
uridine 5.9
EMC 5.9
MSM 5.7
Histidine 5.7
CTP 5.7
CAA 5.7
Amide 5.7
PAM 5.6
PAM 5.6
Proline 5.4
CMP 5.3
GGG 5.3
Pro-Gly 5.2
Guo 5.2
methanethiol 5.2
Agarose 5.1
acrylamide 5.1
TPD 5.1
PAT 5.1
Guo 5.0
UTP 5.0
tryptophan 5.0
tryptophan 5.0
tryptophan 5.0
formamide 5.0
guanidine 5.0
1,4,7,10-tetraazacyclododecane 4.9
proline 4.9
tryptophan 4.8
3-aminobenzamide 4.8
dihydrofolate 4.8
Putrescine 4.7
PDH 4.7
DTT 4.6
alcohol dehydrogenase 4.6
Phenylalanine 4.6
methylhistamine 4.5
Rose Bengal 4.5
Hydroxyurea 4.5
MIA 4.5
Bisulfite 4.4
pyrimidine 4.4
POP 4.4
DEAE 4.4
pyrimidine 4.3
aspartic acid 4.3
DEN 4.3
aspartic acid 4.3
Alanine 4.3
urea 4.2
glutamic acid 4.2
dGTP 4.2
Maps 4.2
Guanine 4.2
aspartic acid 4.2
FK506 4.2
alanine 4.1
His 4.1
D-glucosamine 4.1
dCTP 4.1
asparagine 4.1
Asp 4.1
adenylate 4.1
Actinomycin D 4.0
aspartic acid 4.0
MgCl2 4.0
CDP 4.0
phosphate 4.0
Trypsin 4.0
CPA 3.9
Tris 3.9
GTP 3.8
Chloroquine 3.8
Chloroquine 3.8
Methionine 3.7
Phe 3.7
DTT 3.7
Mg2+ 3.7
Tris 3.7
dATP 3.6
AMP 3.6
Rifampicin 3.6
UGA 3.6
acrylonitrile 3.6
glycerol 3.5
Hoechst 33342 3.5
hydrogen 3.4
A 3 3.4
DSS 3.3
PAM 3.3
phosphoserine 3.3
cGMP 3.3
tyrosine 3.3
S-adenosylhomocysteine 3.2
Adenine 3.2
GSSG 3.2
valine 3.1
phenol 3.1
AAA 3.1
2-propanol 3.1
Cyt 3.1
2-propanol 3.1
FMN 3.1
heptane 3.1
methionine 3.1
threonine 3.1
IMP 3.0
acrylonitrile 3.0
salt 2.9
ANS 2.9
ANS 2.9
isoleucine 2.9
DNP 2.9
lysine 2.9
isoleucine 2.9
Ile 2.9
acetamide 2.8
acetamide 2.8
propylene glycol 2.8
PDB 2.8
GDP 2.8
Gly 2.8
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