Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.27.1 (
RNase
)
16,360
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
RNase
10049
Mol
1843
Sep
1144
DNase
699
RNase A
607
ribonuclease A
570
tRNA
517
polypeptide
391
cytokine
313
glycoprotein
301
ribonucleoprotein
286
lysozyme
282
ATP
268
deoxyribonuclease
262
insulin
247
endonuclease
246
endoplasmic reticulum
241
RNase H
235
Ribonuclease
233
SDS
225
interferon
210
NMR
196
Gen
183
RNase III
179
fused
174
dimeric
172
RNase E
162
angiogenin
159
MRP
149
collagen
149
IL-6
148
polynucleotide phosphorylase
145
Dicer
143
alkaline phosphatase
141
thymus
139
serum albumin
138
DNase I
127
tumor necrosis factor
120
AMP
119
PRI
118
lipopolysaccharide
117
alternatively spliced
115
UTR
115
albumin
114
Poly
110
Pseudomonas
108
acid phosphatase
107
phosphatase
106
membrane-bound
103
eosinophil cationic protein
102
DNA polymerase
101
p53
101
chemokine
100
eosinophil-derived neurotoxin
99
IFN-gamma
98
vitronectin
98
microsomal
96
TNF-alpha
93
GTP
89
chymotrypsin
88
RACE
88
Sp1
85
amylase
84
lectin
83
RNA polymerase II
83
lymphoid
82
RNase H1
82
ATPase
82
lipase
80
histone
78
IGF-I
77
growth hormone
76
estrogen receptor
76
beta-glucuronidase
72
phosphodiesterase
72
Met
72
RNase L
72
IL-1
69
RNP
69
cytochrome c
67
helicase
67
peroxidase
66
beta-actin
66
CD4
65
TGF-beta
65
IL-2
64
neuraminidase
63
PNPase
63
housekeeping
63
RNA polymerase I
61
proteasome
61
IL-10
60
Angiogenin
60
insulin-like growth factor-I
60
genomic clone
60
insulin-like growth factor
59
IL-4
59
RNA-binding protein
59
PARN
58
ribosomal protein
57
caspase-3
56
erythroid
56
IFN
56
fibronectin
55
transferrin
55
DICER1
54
ubiquitin
54
interferon-gamma
54
Cytokine
54
IGF-II
54
hemoglobin
54
CAT
53
beta 1
52
mer
51
IRE1
51
ADP
51
RANTES
50
Pol
50
renin
50
olfactory
50
AP-1
50
threonine
49
tyrosine kinase
48
nerve growth factor
48
catalase
48
thyroid hormone
47
IL-8
47
gut
46
cytochrome
46
insulin-like growth factor I
46
MCP-1
45
Bcl-2
45
LPS
45
vascular endothelial growth factor
45
nuclear protein
45
unknown function
45
GMP
44
angiotensin II
44
FSH
44
interleukin-6
44
Fas
43
nitric oxide synthase
43
myoglobin
43
myosin
43
ACTH
42
beta-globin
42
protein disulfide isomerase
42
tumor necrosis factor alpha
42
cryptic
41
telomeric
41
GH receptor
41
TOF
41
c-myc
39
prolactin
39
epidermal growth factor
39
XBP1
39
RNA helicase
39
membrane protein
39
pseudogene
38
trypsin inhibitor
38
more...
Disease
cancer
782
tumor
730
SDS
225
HIV
206
leukemia
172
hepatocellular carcinoma
159
immunodeficiency
153
carcinoma
152
breast cancer
137
cold
136
virus infection
104
diabetes
101
uterus
89
systemic lupus erythematosus
84
influenza
83
Mycobacterium
74
tumorigenesis
74
tumor growth
74
herpes simplex
72
plaque
72
carcinogenesis
65
melanoma
64
neuroblastoma
62
MCF
60
Alzheimer's disease
58
adenocarcinoma
58
tuberculosis
58
hepatitis C
57
hypertension
56
Epstein
53
pancreatic cancer
52
prostate cancer
51
lymphoma
51
multiple myeloma
50
ischemia
46
sarcoma
46
stomatitis
43
hepatitis B
42
rheumatoid arthritis
41
tumor progression
40
infectious diseases
40
acute myeloid leukemia
39
glioma
39
vaccinia
38
atherosclerosis
37
ovarian cancer
37
metastases
36
AIDS
36
Rous sarcoma
36
lung cancer
36
erythroleukemia
35
epididymis
34
GSH
34
MIP
33
hepatitis
33
obesity
32
gastric cancer
31
squamous cell carcinoma
31
amyotrophic lateral sclerosis
30
Infection
30
colorectal cancer
29
colon cancer
29
cytomegalovirus
29
epithelial ovarian cancer
29
mixed connective tissue disease
28
autoimmune disease
28
chronic myeloid leukemia
28
mole
27
PIN
27
PIN
27
arthritis
26
mole
26
WT1
26
stroke
25
SCID
25
Leukemia
25
heart failure
24
pancreatitis
24
lupus
24
lung carcinoma
24
depression
23
cystic fibrosis
23
scleroderma
23
SEM
23
asthma
22
viral diarrhea
22
Mycoplasma
22
myocardial infarction
22
sepsis
22
pheochromocytoma
22
chronic pancreatitis
22
glioblastoma
21
embryonal carcinoma
20
anemia
20
sepsis
20
cholera
20
lupus
20
bladder cancer
20
dysplasia
19
pneumonia
19
ATM
19
fits
19
Hodgkin's disease
19
acute pancreatitis
19
adenoma
18
malignant mesothelioma
18
multiple sclerosis
18
renal disease
18
dehydration
18
Parkinson's disease
18
acute lymphoblastic leukemia
17
myocardial ischemia
17
chronic lymphocytic leukemia
17
dengue
17
pertussis
17
malnutrition
16
cirrhosis
16
mammary tumor
16
Pituitary
16
osteosarcoma
16
West
16
encephalomyelitis
16
renal failure
15
hepatitis A
15
dementia
15
SLE
15
PHA
14
mouth disease
14
chronic lymphocytic leukemia
14
Burkitt's lymphoma
14
encephalitis
14
Kaposi's sarcoma
14
acute promyelocytic leukemia
14
renal cell carcinoma
14
polymyositis
14
retinoblastoma
14
psoriasis
14
myeloblastosis
13
SARS
13
hyperglycemia
13
seminal vesicles
13
myocarditis
13
Legionella
13
liver cancer
13
chronic renal failure
13
Proteus
13
glomerulonephritis
13
APC
13
myeloid leukemia
13
eosinophilia
13
diabetic nephropathy
12
fibrosarcoma
12
non-small cell lung cancer
12
cornea
12
PSS
12
Schmidt
12
Schistosoma mansoni
12
cervical cancer
12
gastroenteritis
12
CEM
12
more...
Symptom
starvation
102
collapse
20
seizures
19
pain
19
stigma
13
POA
11
anorexia
10
ataxia
8
weakness
7
anesthesia
5
fatigue
5
agitation
5
hyperoxia
5
diarrhea
5
Ill
5
splenomegaly
4
cachexia
4
HSA
4
tremor
4
arthralgia
4
functional recovery
4
acidity
3
Hudson
3
acute stress
3
exhaustion
3
hypothermia
2
CSR
2
erythema
2
female puberty
2
angina
2
memory loss
2
flushing
2
wheezing
1
decreased appetite
1
chills
1
hypotonia
1
discomfort
1
spasm
1
muscle rigidity
1
spasticity
1
colic
1
respiratory distress
1
ACHE
1
RNA marker
1
inanition
1
Halo
1
ophthalmoplegia
1
cough
1
Scratch
1
autodigestion
1
hypercapnia
1
lethargy
1
DNA marker
1
dysarthria
1
masculinization
1
dyspnea
1
pallor
1
sneezing
1
discomfort
1
syncope
1
vomiting
1
paresis
1
physical appearance
1
Drug
lysine
192
DNase I
129
Asn
104
Gel
100
IFN-gamma
95
Pronase
76
IL-2
66
Onconase
60
Dermatol
54
CSF
36
EE2
25
NADH
25
Biopolymers
23
MAP
21
PTH
18
Nephron
18
Retinoic acid
16
IFN-beta
14
Ethanol
14
lactose
13
Cardiovasc
11
Forskolin
11
Herceptin
10
Growth hormone
9
G-CSF
9
p75
9
CaCl2
9
Growth hormone
9
citric acid
9
caffeine
8
CaCl2
8
Fraction
8
CaCl2
8
Alanine
8
ETS
8
ABC
8
FAD
8
Albumin
7
CDP
7
Nephron
7
G418
7
ascorbate
7
-deoxyadenosine
7
Leaf
7
ENT
6
Angiotensin II
6
nitroglycerin
6
CAM
6
Adriamycin
6
ampicillin
6
ADR
6
Activin
6
DHT
5
MgSO4
5
Mutagen
5
VCR
5
Guanidine
5
DHT
5
Paraffin
5
Silica
5
Guanidine
5
SiO2
5
KGF
5
DM1
5
pyridoxal phosphate
5
Bifidobacterium
4
DEX
4
Kenyan
4
ETA
4
Cytidine
4
Gelatin
4
ROS
4
ICI
4
Fragment
4
Estrogens
4
ADM
4
Vitamin A
4
Glutathione
4
Papain
4
IL-11
4
Hypaque
3
Glucagon
3
TTC
3
Capsicum
3
PCB
3
CoCl2
3
CTX
3
CoCl2
3
Heme
3
AZT
3
Nitric Oxide
3
Fluorescein
3
TAT
3
Hypaque
3
PTC
3
Indomethacin
3
IL-1ra
3
Doyle
3
Fluorescein
3
Luteinizing
3
AZT
3
Zein
3
CTC
2
Monit
2
NAG
2
CED
2
Monensin
2
CCL
2
Glutamic acid
2
FeCl3
2
Serum albumin
2
Glycerol
2
TPV
2
Ranitidine
2
ZnCl2
2
Aminoguanidine
2
MRC
2
Cetuximab
2
Histamine
2
ROC
2
Arsenic trioxide
2
PCP
2
Sodium acetate
2
Spectrum
2
THF
2
DMI
2
Spectrum
2
GRF
2
Secretin
2
AGG
2
uPA
2
Imatinib
2
Hyaluronidase
2
DFP
2
Mitogillin
2
VCR
2
CTX
2
CTC
2
balanced salt solution
2
Galactose
2
Dial
2
beta-Galactosidase
2
ZnCl2
2
Troglitazone
2
CTX
2
R1881
2
EPA
2
Lactase
1
Saha
1
Gleevec
1
Calcium chloride
1
CPM
1
EMB
1
Portal
1
NaI
1
2-Methoxyestradiol
1
R-gene
1
Antithrombin III
1
NH3
1
Zinc sulfate
1
more...
Enzyme
RNase
16360
RNase
16062
ribonuclease
6593
ribonuclease
6589
DNase
982
trypsin
424
RNA polymerase
393
reverse transcriptase
323
exoribonuclease
315
RNase T1
291
lysozyme
284
deoxyribonuclease
257
deoxyribonuclease
256
endonuclease
249
RNase H
248
luciferase
220
polynucleotide phosphorylase
182
protein kinase
160
alkaline phosphatase
156
RNase III
147
RNase P
146
DNA polymerase
140
acid phosphatase
124
transcriptase
120
proteinase K
111
S1 nuclease
105
chymotrypsin
105
ATPase
104
catalase
101
chloramphenicol acetyltransferase
98
ERK
94
phosphodiesterase
92
peroxidase
87
lipase
81
proteasome
74
neuraminidase
71
beta-glucuronidase
69
mitogen-activated protein kinase
66
protein kinase C
65
purine nucleoside phosphorylase
64
pepsin
63
beta-galactosidase
58
micrococcal nuclease
51
renin
50
glyceraldehyde-3-phosphate dehydrogenase
47
phospholipase C
46
caspase-3
46
glyceraldehyde-3-phosphate dehydrogenase
45
DNase II
44
venom phosphodiesterase
43
glutathione S-transferase
43
poly(A) polymerase
43
subtilisin
43
RNase PH
43
hyaluronidase
39
alpha-amylase
38
phospholipase A2
38
superoxide dismutase
38
hyaluronidase
36
alpha-sarcin
35
collagenase
35
topoisomerase
34
topoisomerase
34
PNGase F
34
glyceraldehyde-3-phosphate dehydrogenase
33
MIP
32
papain
32
3'-exonuclease
31
P-glycoprotein
31
glyceraldehyde-3-phosphate dehydrogenase
30
glyceraldehyde-3-phosphate dehydrogenase
30
adenylate cyclase
30
focal adhesion kinase
29
ricin
28
ACS
28
RNA ligase
28
NO synthase
28
thrombin
27
lactate dehydrogenase
27
gamma-glutamyl transpeptidase
27
caspase-8
26
thymidine kinase
26
cathepsin D
26
elastase
24
5'-nucleotidase
24
enolase
24
aldolase
22
dihydrofolate reductase
22
RNase D
22
polynucleotide kinase
20
chitinase
20
endoglycosidase H
20
succinate dehydrogenase
19
tyrosine hydroxylase
18
DNA ligase
18
calcineurin
18
DNA ligase
18
deaminase
17
CD10
17
hexosaminidase
16
caspase-9
16
alpha-glucosidase
16
tRNase Z
16
aspartate aminotransferase
16
AMPK
16
phosphofructokinase
16
adenosine deaminase
15
tissue plasminogen activator
15
glucose-6-phosphatase
15
glutathione peroxidase
15
poly(A)-specific ribonuclease
15
invertase
15
adenosine deaminase
15
malate dehydrogenase
14
beta-glucosidase
14
alpha-mannosidase
14
NOS
14
alanine aminotransferase
13
diaphorase
13
APC
13
alcohol dehydrogenase
13
MEK
13
guanylate cyclase
13
thermolysin
13
lipoprotein lipase
12
urease
12
beta-glucosidase
12
cdc2
12
urokinase-type plasminogen activator
12
DNA methyltransferase
12
cytochrome oxidase
12
transglutaminase
12
urease
12
ACE
11
PARP
11
CPR
11
CD13
11
phosphatidylinositol 3-kinase
11
carbonic anhydrase
11
nucleotidase
11
beta-lactamase
11
sulfhydryl oxidase
11
acetylcholinesterase
11
glucose-6-phosphate dehydrogenase
11
thymidylate synthase
10
protein disulfide-isomerase
10
cytidine deaminase
10
PDE
10
cellulase
10
glutamine synthetase
10
kallikrein
9
citrate synthase
9
HSD
9
glutamate dehydrogenase
9
phospholipase D
9
glutamate dehydrogenase
9
sulfatase
9
pectinase
9
oligoribonuclease
9
glutamate dehydrogenase
9
more...
Compound
DNA
2822
Dec
1220
phosphate
528
sodium
515
water
383
sulfate
360
salt
333
Clin
331
lysine
296
His
289
calcium
288
ATP
268
SDS
244
hydrogen
242
DEAE
237
urea
225
arginine
222
methionine
211
uridine
206
glucose
201
tyrosine
201
alanine
200
Mg2+
196
leucine
191
oxygen
181
cysteine
175
ammonium
173
acetate
169
EDTA
166
EDTA
166
zinc
157
phenol
156
cAMP
155
galactose
153
ethanol
148
pyrimidine
147
pyrimidine
147
Phe
139
Asp
135
serine
134
bromide
127
AMP
125
threonine
117
manganese
108
tryptophan
101
proline
97
nitrogen
95
GTP
91
potassium
90
PEG
89
iron
88
tryptophan
86
tryptophan
85
tryptophan
85
iodine
84
GMP
84
Triton X-100
81
retinoic acid
81
Gly
80
Guo
79
acrylamide
78
NH2
74
glycerol
74
HCl
73
guanidine
70
nitric oxide
70
COS
69
asparagine
64
40S
62
chloroform
61
copper
60
GlcNAc
59
TCA
57
CAT
53
CAT
53
CAT
53
PEG
53
ADP
52
adenylate
51
ADP
51
ADP
51
acridine
49
glutamate
49
UTP
48
glutamic acid
48
formamide
47
Tris
47
phosphorus
45
Insulin
45
formaldehyde
45
silver
45
methanol
43
Tris
42
Ile
42
TOF
41
Sucrose
40
cGMP
39
aspartic acid
39
acetone
39
formaldehyde
39
aspartic acid
38
aspartic acid
38
aspartic acid
38
cobalt
38
TNF
38
CMP
37
GSH
37
GSH
37
acetic acid
36
valine
35
MgCl2
35
glutamine
35
UMP
32
aldosterone
32
ACTH
32
NAD
31
CMP
30
ACS
29
creatinine
28
ACS
28
MTT
27
perchloric acid
27
PIN
27
Optimal
27
hydroxide
27
PMA
26
PAM
26
PAM
26
MDA
25
nitrate
25
CTP
25
NADH
25
CO2
25
Estradiol
25
PMA
23
GABA
22
Estrogen
22
Inositol
22
GABA
21
Estrogen
21
aldehyde
21
cadmium
21
isopropanol
21
THP
20
2-mercaptoethanol
20
H2O2
20
NADPH
20
NADPH
20
TSH
20
Triton
19
Neuronal
19
CAM
19
5-HT
19
Trypsin
19
gamma-aminobutyric acid
19
Cycloheximide
19
THP
19
NAD
19
nickel
18
ADP-ribose
18
more...