Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.27.1 (
RNase
)
16,360
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The specificity of the lysosomal
acid RNase
[
Saha
, B.K., Graham, M.Y. and Schlessinger, D. (1979). J. Biol. Chem. 5951-5957] has been determined by 5'-end labeling and sequencing gel electrophoresis of rRNA. The enzyme has a predilection for the dinucleotide sequence ...NU..., which is cleaved into ...Np and HOU.... Sequences AU and GU sequences is enhanced by the presence of adjacent purine residues. The specificity remains unaltered after partial denaturation of the RNA.
...
PMID:Specificity of acid RNase from HeLa cell lysosomes. 703 25
