Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.26.9 (ribonuclease)
6,589 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It was shown that at 37 degrees C nitrosomethylurea causes an 8-fold increase (as compared to the normal) of the activity of alkaline ribonuclease. 1,4-Bis-diazoacetylbutane also activated alkaline ribonuclease at 37 degrees C. A dependence of the effect of chemical mutagens studied on the activity of alkaline ribonuclease on their concentration was observed. The activation of ribonuclease by NMU and DAB affords a possibility to understand the molecular mechanisms of the action of chemical mutagens on the metabolism.
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PMID:[Effect of nitrosomethylurea and 1,4-bis-diazoacetylbutane on alkaline ribonuclease activity]. 101 Mar 19