Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.26.5 (
RNase P
)
1,348
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Although the structure of the catalytic RNA component of
ribonuclease P
has been well characterized in Bacteria, it has been little studied in other organisms, such as the Archaea. We have determined the sequences encoding
RNase P
RNA in eight euryarchaeal species: Halococcus morrhuae, Natronobacterium gregoryi, Halobacterium cutirubrum, Halobacteriurn trapanicum, Methanobacterium thermoautotrophicum strains deltaH and Marburg, Methanothermus fervidus and Thermococcus celer strain
AL-1
. On the basis of these and previously available sequences from Sulfolobus acidocaldarius, Haloferax volcanii and Methanosarcina barkeri the secondary structure of
RNase P
RNA in Archaea has been analyzed by phylogenetic comparative analysis. The archaeal RNAs are similar in both primary and secondary structure to bacterial
RNase P
RNAs, but unlike their bacterial counterparts these archaeal
RNase P
RNAs are not by themselves catalytically proficient in vitro.
...
PMID:Comparative analysis of ribonuclease P RNA structure in Archaea. 861 27
