Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.26.4 (RNase H)
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Human Gene/Protein
KIAA0323 13.5
RNase H 13.5
Ribonuclease H2 subunit A 12.3
RNase H1 12.1
putative reverse transcriptase 11.6
ribonuclease H1 11.6
DNA-dependent DNA polymerase 11.3
p66 RT 11.2
DNA-directed DNA polymerase 11.0
p66 10.9
RNASEH1 10.8
GIN1 10.7
THP2 10.7
Bystin 10.5
RNH1 10.5
Adam33 10.3
RNA-directed DNA polymerase 10.3
PPT2 10.3
ribonuclease H2 10.0
Pol protein 10.0
zinc finger protein 185 9.9
U11/U12 9.8
enhancer of zeste homolog 1 9.8
p15 protein 9.8
RNASEH2B 9.7
DEDD 9.7
p51 9.6
serine:pyruvate aminotransferase 9.6
N4BP1 9.6
VARS 9.6
ZMYM3 9.6
CBF5 9.6
gag-pro-pol 9.5
MYM 9.5
Nucleocapsid protein 9.3
PRP17 9.3
PRP22 9.3
pol protein 9.3
H63 9.3
PRP16 9.1
PRP8 9.1
LTV1 9.1
mutated in colorectal cancers 9.1
Slu7 9.1
COQ6 9.0
Hox-1.4 9.0
PRP4 9.0
ushA 8.9
SLA1 8.9
ubiquitously expressed transcript 8.9
insulin receptor precursor 8.9
PAF49 8.9
XRN2 8.8
SMG5 8.8
U1-C 8.7
PA2G4 8.7
THO 8.7
SMG6 8.6
DBR1 8.6
RNASEH2A 8.6
P145 8.5
P66 8.5
U26 8.5
Dia2 8.5
integrase 8.4
DNA topoisomerase III 8.4
PRP2 8.4
tRNA-Arg 8.4
MOV10 8.3
3'-5' exonuclease 8.2
senataxin 8.2
TREX1 8.2
ORF 1 8.2
splicing factor SF2 8.1
ORF-3 8.1
RCOR1 8.1
Metnase 8.0
prothymosin-alpha 8.0
NF110 7.9
DNA polymerase 7.9
interleukin-5 receptor 7.9
DDX5 7.8
DNA primase 7.8
RBM4 7.7
RNase 7.7
PPT1 7.7
poly(A)-specific ribonuclease 7.7
MF1 7.7
58kDa 7.7
CKIP-1 7.7
MMS2 7.6
RP-A 7.6
p68 7.6
PIWI 7.6
HIPK3 7.6
C1 protein 7.6
Fanconi anemia protein 7.6
tropomyosin 1 7.6
alpha II 7.6
IL-20R2 7.6
DNA ligase 7.5
HNP-3 7.5
DDX17 7.5
LIG3 7.5
RNP antigen 7.5
PPT 7.5
small nuclear ribonucleoprotein 7.5
small nuclear ribonucleoprotein particle 7.5
SETX 7.5
RISC 7.5
snRNP 7.4
ZNF9 7.4
uroplakin II 7.4
P120 7.4
translin 7.4
ribosomal protein S15 7.4
DNA directed 7.4
TEL1 7.4
GSTM2 7.4
Mtr4 7.4
Ribonuclease 7.4
flap endonuclease 1 7.4
POLR2A 7.3
cleavage stimulation factor 7.3
RAP30 7.3
SRp40 7.3
maelstrom 7.3
ENA 7.3
S100A14 7.3
1C5 7.3
ribosomal protein L9 7.3
cleavage and polyadenylation specificity factor 7.2
K38 7.2
RNase A 7.2
RNA-dependent ATPase 7.2
DNA ligase I 7.2
single-stranded DNA binding protein 7.2
PABP1 7.1
Integrase 7.1
pol 7.1
p68 RNA helicase 7.1
LPAR1 7.1
DNA polymerase alpha 7.1
Exonuclease III 7.0
A49 7.0
Mullerian inhibiting substance 7.0
ICAM-1 mRNA 7.0
ssDNA binding protein 7.0
Multidrug resistance protein 7.0
DDX1 7.0
DNA-directed RNA polymerase 7.0
P51 6.9
Uracil-DNA glycosylase 6.9
metavinculin 6.9
AGO4 6.9
p54 6.9
RING1B 6.9
PiT-1 6.9
DEAD box protein 6.9
AGU 6.9
more...
Disease
myeloblastosis 9.3
Sluder 7.9
Rous sarcoma 6.7
avian sarcoma 6.6
Human immunodeficiency virus type 6.4
retroviral disease 6.2
Chronic hepatitis B 6.0
Kaposi's Sarcoma 6.0
myoblastoma 5.9
immunodeficiency 5.8
AIDS/HIV 5.8
Vidal 5.8
XPG 5.6
Enzyme inhibition 5.5
AHL 5.5
ACS1 5.4
NCR 5.3
CMD 5.3
HIV 5.3
CMD 5.3
Ullrich 5.2
PIN 5.2
reticuloendotheliosis 5.1
B virus infection 5.1
WSN 5.1
WSN 5.1
SDA 5.1
Vogt 5.0
bovine leukemia 4.9
Vesicular stomatitis 4.8
Machado-Joseph disease 4.7
Frontotemporal dementia 4.6
HML 4.5
avian leukosis 4.5
scalded skin syndrome 4.4
hepatitis B 4.4
leukemia 4.4
PIN 4.3
FTC 4.2
chlorosis 4.0
monocytic leukemia 3.9
roundworm 3.9
TCC 3.8
MSA 3.8
DM2 3.8
histiocytic lymphoma 3.7
brain disorder 3.7
MAR 3.7
African swine fever 3.7
coxsackievirus 3.6
HTS 3.6
Foot-and-mouth disease 3.5
RDS 3.5
Testis 3.5
Testis 3.5
TAS 3.5
Friedreich's ataxia 3.5
Roth 3.4
RHE 3.4
hereditary hemochromatosis 3.2
Dissociation 3.2
Duchenne muscular dystrophy 3.2
mixed connective tissue disease 3.2
neuromuscular disorder 3.1
hepatitis C 3.1
CEM 3.0
DM1 3.0
histiocytic lymphoma 3.0
TTP 3.0
monoclonal gammopathy of undetermined significance 2.9
stuttering 2.9
mammary tumor 2.8
SAD 2.8
AIDS 2.8
embryonal carcinoma 2.8
CSA 2.8
Huntington's disease 2.8
stomatitis 2.7
yellow fever 2.7
AS1 2.6
Gilbert 2.6
Jensen 2.6
erythroleukemia 2.5
mouth disease 2.5
vaccinia 2.4
Leukemia 2.4
TTP 2.4
herpes simplex 2.4
WRN 2.4
Schistosoma japonicum 2.4
Kaposi's sarcoma 2.4
lipodystrophy 2.4
idiopathic thrombocytopenic purpura 2.4
sarcoma 2.3
HTLV-I 2.3
Thymus 2.2
Thymus 2.2
Thymus 2.2
GAD 2.2
adult T-cell leukemia/lymphoma 2.2
human papilloma virus 2.2
human papilloma virus 2.2
Schmidt 2.1
viral diarrhea 2.1
MTS 2.1
hepatoblastoma 2.1
SDS 2.0
EMT 2.0
xeroderma pigmentosum 2.0
African trypanosomiasis 2.0
Shigella flexneri 1.9
PLS 1.9
Burkitt's lymphoma 1.9
ATM 1.8
hemolytic uremic syndrome 1.8
latent infection 1.8
polycythemia vera 1.8
hemochromatosis 1.7
lymphocytosis 1.7
cytomegalovirus 1.7
opportunistic infection 1.7
diabetes insipidus 1.7
bends 1.7
insulinoma 1.7
immune deficiency 1.6
SAR 1.6
lymphoblastic leukemia 1.6
acute promyelocytic leukemia 1.6
polyneuropathy 1.6
transitional cell carcinoma 1.6
chronic hepatitis 1.5
virus infection 1.5
herpes 1.4
Mycobacterium 1.4
influenza 1.4
Hashimoto's thyroiditis 1.4
Blocking 1.3
multiple endocrine neoplasia 1.3
ABL 1.3
chronic myeloid leukemia 1.3
Ewing's sarcoma 1.3
pheochromocytoma 1.2
dengue 1.2
SCH 1.2
viremia 1.2
acute hepatitis 1.2
respiratory infection 1.2
leprosy 1.2
anemia 1.2
vagina 1.1
DDP 1.1
lung metastases 1.1
chronic lymphocytic leukemia 1.1
SCID 1.1
liver cancer 1.0
mimicry 1.0
parvovirus 1.0
muscular dystrophy 1.0
Adhesion 1.0
amyloidosis 1.0
more...
Symptom
Halo 4.7
Hudson 3.4
collapse 0.3
stigma -0.2
weakness -1.7
pain -4.5
Drug
Reverset 10.5
Hexitol 9.6
Mercaptopurine 8.1
Genasense 7.7
AZT 6.3
CPZ 6.2
AZT 6.1
EFV 5.9
Raltegravir 5.7
RbCl 5.4
RbCl 5.4
AGG 4.9
MEA 4.7
DNase I 4.6
PFA 4.5
-deoxyadenosine 4.5
Glide 4.2
Adenosine deaminase 4.1
Asn 4.0
Fragment 3.9
DM1 3.9
Gel 3.7
TAK 3.5
Luteinizing 3.5
G418 3.4
MRC 3.3
Glycerol 3.3
Fraction 3.2
Meth 3.1
Alanine 3.1
Glycyrrhiza 3.0
MgSO4 2.9
GEO 2.9
Ranitidine 2.9
TAC 2.8
ACT 2.4
TAT 2.3
ETS 2.1
ETA 2.1
Biopolymers 2.0
IFN-beta 1.9
ADM 1.9
lysine 1.7
HCH 1.7
p75 1.6
nitroglycerin 1.4
CaCl2 0.9
CaCl2 0.9
CaCl2 0.8
NH3 0.7
Leaf 0.7
IFN-gamma -1.3
IL-2 -1.3
Monit -1.6
Enzyme
RNase H 13.5
exoribonuclease H 12.5
yeast ribonuclease 11.9
CobC 11.8
L-serine hydro-lyase 9.5
opine dehydrogenase 9.5
RNase D 9.4
3'-exonuclease 8.8
beta-phosphoglucomutase 8.5
reverse transcriptase 8.4
oligoribonuclease 8.3
venom phosphodiesterase 8.2
Escherichia coli exonuclease III 8.2
DNA polymerase 7.9
endonuclease VII 7.8
RNase T1 7.6
poly(A)-specific ribonuclease 7.6
aminoglycoside 6'-N-acetyltransferase 7.5
RNase 7.5
RNase 7.4
RNA ligase 7.4
poly(A)-specific ribonuclease 7.2
deoxycytidine deaminase 7.1
ribonuclease 7.1
ribonuclease 7.0
HIV-1 protease 7.0
DNA ligase 6.9
DNA ligase 6.9
RNase PH 6.8
phosphatidylglycerophosphate synthase 6.8
dUTPase 6.8
lambda exonuclease 6.8
RNase III 6.7
L-serine dehydratase 6.7
endodeoxyribonuclease 6.4
pseudouridine synthase 6.2
S1 nuclease 6.2
3'-phosphatase 6.1
peptidylarginine deiminase 6.0
endonuclease 6.0
exoribonuclease 6.0
micrococcal nuclease 5.9
N-acetylglucosaminyltransferase I 5.9
transcriptase 5.8
DNase II 5.8
alpha-sarcin 5.7
polynucleotide kinase 5.7
AP lyase 5.6
LexA repressor 5.6
RNA polymerase 5.4
RNase P 5.4
alanine dehydrogenase 5.4
p80 5.4
PAT 5.4
DNase 5.4
poly(A) polymerase 5.1
tryptophan synthase 5.1
propionyl-CoA carboxylase 5.1
propionyl-CoA carboxylase 5.1
polynucleotide phosphorylase 5.0
pullulanase 5.0
deoxyribonuclease 5.0
isoamylase 5.0
cytosine deaminase 5.0
ACC synthase 4.8
lysine decarboxylase 4.8
carnitine acetyltransferase 4.8
Protein 2 4.8
S-adenosylmethionine decarboxylase 4.7
DMT 4.6
cytidine deaminase 4.6
deoxyribonuclease 4.5
arginine decarboxylase 4.4
SPT 4.4
pectate lyase 4.3
topoisomerase 4.2
arginine decarboxylase 4.2
topoisomerase 4.2
thermolysin 4.2
arylalkylamine N-acetyltransferase 4.1
peptidyl-prolyl cis-trans isomerase 3.9
BAT 3.8
glutaminase 3.6
cystathionine beta-synthase 3.6
angiotensin-converting enzyme 2 3.5
lysin 3.5
5alpha-reductase 3.4
5alpha-reductase 3.4
chloramphenicol acetyltransferase 3.2
proteinase K 3.1
firefly luciferase 3.1
transpeptidase 3.0
triphosphatase 2.9
polo-like kinase 1 2.9
CPT 2.9
ricin 2.9
DNA methyltransferase 2.8
phosphodiesterase 2.8
ornithine transcarbamylase 2.8
CPT 2.7
endoglycosidase H 2.7
beta-galactosidase 2.7
dihydrofolate reductase 2.6
glucoamylase 2.5
glutamate decarboxylase 2.4
chaperonin 2.4
phosphoglycerate kinase 2.4
CPT 2.3
N-acetyltransferase 2.3
TAT 2.3
histidine kinase 2.3
deaminase 2.2
demethylase 2.1
ribonucleotide reductase 2.0
ribonucleotide reductase 1.9
ATPase 1.8
aldolase 1.7
hydrogenase 1.7
hydrogenase 1.7
thymidylate synthase 1.7
nitrogenase 1.7
luciferase 1.6
cathepsin D 1.5
xylanase 1.4
acid phosphatase 1.4
lysozyme 1.4
glyceraldehyde-3-phosphate dehydrogenase 1.4
CAD 1.4
glyceraldehyde-3-phosphate dehydrogenase 1.4
xylanase 1.4
CAD 1.4
CAD 1.3
glyceraldehyde-3-phosphate dehydrogenase 1.3
invertase 1.2
adenosine deaminase 1.2
adenosine deaminase 1.2
pyruvate kinase 1.1
CPR 1.1
hexokinase 1.1
chymotrypsin 1.1
pyruvate dehydrogenase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.0
glutathione S-transferase 1.0
caspase-1 0.9
ornithine decarboxylase 0.9
glyceraldehyde-3-phosphate dehydrogenase 0.8
ACS 0.8
beta-lactamase 0.8
prostate-specific antigen 0.7
ATP synthase 0.7
tyrosine hydroxylase 0.6
thymidine kinase 0.6
thrombin 0.5
gamma-glutamyl transpeptidase 0.4
protein kinase C -0.1
AMP-activated protein kinase -0.2
P-glycoprotein -0.2
PARP -0.2
trypsin -0.3
lactate dehydrogenase -0.3
more...
Compound
ethylenesulfonic acid 11.9
ethylenesulfonic acid 11.9
4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid 11.9
4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid 11.9
Quinhydrone 11.5
C15H20O3 10.7
Aminothiazole 10.2
4-Thiouridine 8.8
Ribose, 8.3
2-hydroxy-1-naphthaldehyde 7.8
2-hydroxy-1-naphthaldehyde 7.8
2-hydroxy-1-naphthaldehyde 7.8
2-hydroxy-1-naphthaldehyde 7.7
2-hydroxy-1-naphthaldehyde 7.7
Nevirapine 7.7
2-hydroxy-1-naphthaldehyde 7.6
2-hydroxy-1-naphthaldehyde 7.6
Bergenin 7.6
L-chicoric acid 7.6
dITP 7.5
1-cyclohexene 7.5
Castanospermine 7.2
Ingenol 7.2
propionyl-coenzyme A 7.1
Efavirenz 7.0
oxetane 6.9
cycloheptane 6.9
2-butenyl 6.8
2-butenyl 6.7
2-hydroxybenzaldehyde 6.7
AG-3 6.6
cyclooctane 6.6
(-)-quinic acid 6.5
Paromomycin 6.5
dGTP 6.4
Captan 6.4
Lupeol 6.2
TMG 6.2
AZT 6.0
CPZ 6.0
dCTP 5.9
TTP 5.9
FB2 5.8
dCMP 5.8
dATP 5.8
40S 5.8
Foscarnet 5.7
3TC 5.7
DAMP 5.6
1H-pyrrole 5.6
1H-pyrrole 5.6
AET 5.6
2-furaldehyde 5.5
2-deoxystreptamine 5.5
PAT 5.5
BIP 5.4
S 1 5.4
dGMP 5.4
6-aminohexanoic acid 5.4
6-aminohexanoic acid 5.4
methylguanosine 5.3
Betulinic acid 5.3
AAB 5.3
AAB 5.3
TAR 5.3
Ribose 5.0
2-methoxyethyl 5.0
2-methoxyethyl 5.0
UMP 4.9
PIN 4.9
MCE 4.9
fMet 4.9
Actinomycin D 4.9
TBC 4.9
Guo 4.9
6-Mercaptopurine 4.8
APT 4.8
Mg2+ 4.8
MAD 4.8
MEA 4.7
cinnamyl 4.7
BIC 4.6
MgCl2 4.6
DMT 4.6
SDA 4.5
CTP 4.5
Busulfan 4.5
H-3 4.5
[1,10]phenanthroline 4.5
UTP 4.5
m-AMSA 4.5
aminomethyl 4.4
DBU 4.4
ANA 4.4
ANA 4.4
Rhodamine 123 4.4
formamide 4.4
manganese 4.4
DMT 4.4
carbamyl phosphate 4.3
DNA 4.3
NMP 4.3
DDE 4.3
Deoxyribonucleic acid 4.2
dUMP 4.2
TET 4.2
TET 4.2
TMC 4.1
Chlorpromazine 4.0
Amikacin 3.9
Polyamine 3.9
pentaerythritol 3.9
DEA 3.9
DEA 3.9
DEAE 3.9
tryptophan 3.9
Azole 3.8
DEA 3.8
INT 3.8
TAA 3.8
HMM 3.8
Polypeptide 3.8
pyrimidine 3.7
TCC 3.7
guanidine 3.7
uridine 3.7
tetraphosphate 3.6
pyrimidine 3.6
Purine 3.6
SAD 3.6
DRB 3.6
Coumarin 3.6
hydroxyglutarate 3.6
NEM 3.6
Methionine 3.6
PABA 3.5
Piper 3.5
1H-pyrazole 3.5
Acyclovir 3.5
aspartic acid 3.5
NPA 3.5
aspartic acid 3.5
aspartic acid 3.5
salicylaldehyde 3.4
salicylaldehyde 3.4
salicylaldehyde 3.4
salicylaldehyde 3.4
salicylaldehyde 3.4
Asp 3.4
cyclopentane 3.4
salicylaldehyde 3.4
DAG 3.4
DMD 3.3
Alizarin 3.3
Carnitine 3.3
Hydroxyurea 3.3
nonyl 3.3
1H-pyrazole 3.3
XTT 3.2
PAN 3.2
more...