Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.1.25.1 (deoxyribonuclease)
 1,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Lecithin and lecithin/cholesterol liposomes formed in aqueous solutions of DNA entrap covalently closed circular, open circular and linear DNA molecules of size up to at least 13 kilobases. The sequestered DNA molecules are efficiently protected against exogenous deoxyribonuclease action although nicking and linearization of circular DNA can be observed. The size of these liposomes ranges from approximately 0.5 to 7.5 mu with an average of 2.5--4 mu. DNA filled liposomes strongly interact with plant protoplasts under conditions inducing protoplast fusion. Results suggest that sequestered plasmid DNA can be transferred to protoplast nuclei.
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PMID:Entrapment of plasmid DNA by liposomes and their interactions with plant protoplasts. 49 23

Thiol-activated extracellular hemolysin produced by a strain of Propionibacterium avidum was partially purified and several properties were examined. The hemolysin was heat labile and inactivated by proteases and deoxyribonuclease. Hemolysin adsorbed to erythrocytes at 0 degrees C. Cu++ at 1 mM inhibited hemolysis partially. Lecithin prevented the activity completely. The hemolytic spectrum was relatively wide and the activity was high with rabbit, dog, horse, and pig erythrocytes.
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PMID:Hemolysin of Propionibacterium avidum. 675 Sep 80