Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.22.1 (
DNase II
)
429
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The degradation of DNA in modified deoxyribonucleoprotein samples by
DNase II
in the presence of a polyanion (polypentose sulphate) was studied. The behaviour of
DNP
samples partially depleted of histone and treated with acetic anhydride is characterized by an increased accessibility of their DNA to
DNase II
, by a decreased polyanion amount needed for the maximum enzymatic degradation of their DNA, and, finally, by a more profound inhibitory effect of higher polyanion amounts on the
DNase II
-catalyzed degradation. On the other hand, the behaviour of
DNP
samples treated with formaldehyde is characterized by a decreased accessibility of their DNA to
DNase II
, by a limited increase in the enzymatic degradation of their DNA in the presence of the polyanion, and finally by a less profound inhibitory effect of higher polyanion amounts on the
DNase II
-catalyzed degradation.
...
PMID:The effect of polyanion on the enzymatic degradation of modified deoxyribonucleoprotein samples. 57 7
