Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.22.1 (DNase II)
429 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Oral administration of lantana leaf powder to guinea pigs caused an increase in the hepatic postmitochondrial fraction:homogenate ratios of activities of lysosomal enzymes--acid phosphatase, cathepsin B and DNase II. Enzyme activities of glucokinase, aldolase, lactate dehydrogenase and glucose-6-phosphate dehydrogenase were elevated whereas activity of glutathione-S-transferase decreased. Alterations in the activities of lysosomal and cytosol enzymes appear to constitute an important biochemical lesion in the pathogenesis of guinea pig liver in lantana toxicity.
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PMID:Effect of lantana toxicity on lysosomal and cytosol enzymes in guinea pig liver. 683 12