Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.21.3 (deoxyribonuclease)
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Human Gene/Protein
deoxyribonuclease 13.5
Ubiquitin B 12.8
TNFRSF1A-associated via death domain 12.0
HTF9 11.5
RPC3 11.3
GGTA 11.2
TMPRSS9 11.2
ANKRD30A 11.2
DNASE1L3 11.1
DNase gamma 11.0
B-ind1 11.0
DNASE1 10.9
ADCY7 10.9
DLAD 10.7
Caspase-activated DNase 10.7
deoxyribonuclease II 10.6
CDCA3 10.5
death effector domain-containing 10.5
ITM2A 10.4
Fc gamma receptor IIB 10.4
DFF35 10.4
SPF30 10.3
acid DNase 10.2
THIK-2 10.1
aminomethyltransferase 10.0
SPC24 10.0
TRIP-1 10.0
Hpa2 9.9
NUCKS1 9.9
SSBP3 9.9
DNase II 9.9
KCTD11 9.8
transcription regulator protein 9.6
Ten-m3 9.6
SLP2 9.5
ATPase II 9.5
DNase X 9.3
MT-IG 9.3
heparanase 2 9.3
ITGAL 9.3
DNA methylase 9.2
PIP5K1C 9.2
UBE2I 9.1
NBG 9.1
KR2 9.0
TNF receptor-associated protein 1 9.0
histone H1t 8.9
ATP synthase subunit beta 8.9
adenylyl cyclase-associated protein 8.8
MOBP 8.8
BNC1 8.8
stanniocalcin 2 8.7
CCL14 8.7
phosphomonoesterase 8.6
Exonuclease I 8.6
CRISP1 8.6
S1-5 8.6
KNS 8.6
Exonuclease III 8.5
RR1 8.4
DNase 8.4
caspase-activated DNase 8.4
carbonic anhydrase B 8.4
GATC 8.3
parotid secretory protein 8.3
ADN 8.3
deoxyribonuclease I 8.3
pancreatic cholesterol esterase 8.3
TNFRSF10B 8.2
beta-polymerase 8.2
exonuclease 1 8.2
NDST1 8.2
FCGR2B 8.1
DNA replication licensing factor 8.1
CRV 8.1
Ribonuclease 8.1
SP-10 8.1
ISG20 8.1
high molecular weight mucin 8.0
NAK 8.0
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Disease
Pleural infection 12.5
Mammary adenocarcinoma 10.0
KNS 9.1
latent virus infection 8.9
Streptococcus pyogenes infection 8.4
Myometrium 8.4
Alveolar rhabdomyosarcoma 8.3
throat infection 8.2
streptococcal infection 7.4
Staphylococcus aureus endocarditis 7.3
acute bronchiolitis 7.0
Trichinella infection 7.0
DBA2 6.8
oophoritis 6.8
streptococcal pharyngitis 6.7
plantar warts 6.6
Brucella canis 6.5
glomerulitis 6.5
tonsillar hypertrophy 6.5
erysipelas 6.5
Autosomal recessive polycystic kidney disease 6.3
IS3 6.3
impetigo 6.2
Shigella sonnei 6.2
rheumatic fever 6.2
HMS 6.2
recurrent tonsillitis 6.0
acute glomerulonephritis 6.0
empyema 6.0
Shwartzman reaction 5.9
RP4 5.9
sclerodactyly 5.8
carditis 5.8
acute tonsillitis 5.7
coryza 5.7
Brucella suis 5.7
RP1 5.7
CDT 5.6
Vesicular stomatitis 5.6
pyoderma 5.6
trichinellosis 5.6
pharyngitis 5.4
community acquired pneumonia 5.4
sicca syndrome 5.4
IS1 5.2
SSD 5.2
tracheomalacia 5.1
juvenile periodontitis 5.1
reticuloendotheliosis 5.0
cystic fibrosis 4.9
skin infection 4.9
Franklin 4.9
lymphogranuloma venereum 4.9
CREST 4.9
NPS 4.9
KPC 4.8
pulmonary insufficiency 4.7
NLS 4.7
Lymph nodes 4.7
lung abscess 4.6
parakeratosis 4.6
rind 4.6
CEP 4.5
ABS 4.5
orf 4.5
chancroid 4.5
Haemophilus 4.4
ABS 4.4
myeloblastosis 4.4
tinea 4.4
DMS 4.4
autoimmune thyroiditis 4.4
carcinosarcoma 4.4
Proteus 4.3
avian leukosis 4.3
Venezuelan equine encephalitis 4.3
dermatophytosis 4.2
Mycoplasma 4.2
rheumatic heart disease 4.2
Reiter's syndrome 4.1
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Symptom
nocturnal cough 7.5
POA 5.3
adenitis 5.2
persistent cough 5.1
clubbing 4.5
chorea 4.3
Hudson 4.3
muscle rigidity 4.3
sore throat 3.9
acute abdominal pain 3.4
chronic cough 3.4
twitching 3.4
cough 3.1
masculinization 3.0
Ill 2.5
dyspnea 2.2
starvation 2.1
hemoptysis 1.8
arthralgia 1.5
respiratory distress 1.1
agitation 0.8
erythema 0.7
exhaustion 0.6
anorexia 0.6
collapse 0.5
acidity 0.5
tremor 0.2
diarrhea 0.1
discomfort -0.1
discomfort -0.2
vomiting -0.6
pain -1.6
Drug
Pulmozyme 11.3
Pronase 8.6
Nafcillin 8.4
Neocarzinostatin 7.6
CrCl3 6.8
DNase I 6.8
Mitomycin-C 6.7
Alteplase 6.5
Kaolin 6.4
Alteplase 6.4
Rasburicase 6.4
Alteplase 6.2
CED 6.2
ZnCl2 5.6
ZnCl2 5.6
Hyaluronidase 5.5
anti-RSV 5.5
Hyaluronidase 5.4
Glutamic acid 5.4
TES 5.2
Lactose 5.2
Metrizamide 5.1
Colistin 4.9
Camp 4.8
Fraction 4.6
FLP 4.3
ABC 4.2
Hypaque 4.2
lactose 4.1
Hypaque 4.1
CaCl2 4.0
CaCl2 4.0
Arsenic trioxide 4.0
CaCl2 4.0
IPM 3.8
Amiloride 3.8
Coral 3.7
Activin 3.6
Gelatin 3.6
Amiloride 3.5
Gel 3.5
ampicillin 3.5
Itraconazole 3.4
-deoxyadenosine 3.3
DHT 3.2
DHT 3.2
Glycerol 3.2
Alanine 2.9
MOF 2.8
HCH 2.6
lysine 2.3
Adriamycin 2.2
Albumin 2.1
NADH 1.9
Asn 1.8
Bifidobacterium 1.8
Mutagen 1.8
PTH 1.6
NH3 1.6
Leaf 1.5
THF 1.4
ROS 1.1
CTX 1.0
MAP 0.4
Nephron 0.2
caffeine -0.1
ascorbate -0.1
IL-2 -0.5
CSF -0.6
Dermatol -0.8
Enzyme
deoxyribonuclease 14.3
restriction-modification system 14.1
deoxyribonuclease 14.0
yeast ribonuclease 12.8
DNase 11.7
type II restriction enzyme 11.3
L-fucose dehydrogenase 10.8
exodeoxyribonuclease 10.6
DNase II 10.4
DNA methyltransferase 10.3
ribonuclease 9.6
ribonuclease 9.6
exonuclease V 9.5
rubredoxin reductase 9.4
dCTPase 9.4
2',3'-cyclic nucleotide phosphohydrolase 9.0
rhizopuspepsin 8.9
GDP-mannose 4,6-dehydratase 8.7
PGE2-9-ketoreductase 8.7
lambda exonuclease 8.7
phospho-beta-glucosidase 8.6
deoxyribose-5-phosphate aldolase 8.5
diacetyl reductase 8.5
RNase 8.3
agmatine deiminase 8.3
endodeoxyribonuclease 8.2
RNase 8.2
exonuclease I 8.1
3'-phosphatase 7.9
amylomaltase 7.7
L-serine dehydratase 7.5
ribokinase 7.5
endonuclease 7.5
Escherichia coli exonuclease III 7.5
T-protein 7.3
lysine decarboxylase 7.3
venom phosphodiesterase 7.1
hyaluronate lyase 7.1
micrococcal nuclease 7.1
hyaluronidase 7.0
protein disulfide-isomerase 7.0
lysostaphin 7.0
arginine deiminase 6.9
dCMP deaminase 6.9
carboxypeptidase G2 6.8
hyaluronidase 6.7
3'-exonuclease 6.7
uracil phosphoribosyltransferase 6.7
p-nitrophenylphosphatase 6.6
endonuclease VII 6.6
uridine kinase 6.6
alpha-sarcin 6.6
acylphosphatase 6.5
histidase 6.5
ADP-ribosyltransferase 6.3
proteinase A 6.3
conjugase 6.2
thymidylate kinase 6.2
chondroitinase 6.2
sortase A 6.1
spermidine synthase 6.0
DNA polymerase 6.0
orotidine-5'-phosphate decarboxylase 6.0
RNase III 5.9
ADP-ribosyltransferase 5.9
DNA ligase 5.9
DNA ligase 5.9
lysin 5.9
ficin 5.9
peptidylarginine deiminase 5.9
nitrile hydratase 5.9
triphosphatase 5.8
cathepsin C 5.7
beta-xylosidase 5.7
trypsin 5.7
chymopapain 5.7
heparinase 5.6
NAD glycohydrolase 5.6
chymopapain 5.6
lipase 5.6
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Compound
Dehydroheliotridine 13.3
Nitromin 11.3
Gallocyanin 11.0
Pyridoxamine 5'-phosphate 10.9
Carboquone 9.0
Carboquone 9.0
Carboquone 9.0
Carboquone 9.0
Chondroitin sulfate A 8.5
Coumermycin 8.5
Picric acid 8.5
Nafcillin 8.4
Atractyloside 8.2
Chromomycin A3 8.2
Distamycin A 8.1
Deoxyribonucleic acid 8.1
1,2,3-trichloropropane 7.9
R 1881 7.9
Potassium permanganate 7.6
IBT 7.6
Oil Red 7.6
Neocarzinostatin 7.6
ASK 7.4
DTB 7.2
DTB 7.2
M 3 7.2
Pristane 7.2
DTB 7.2
Coomassie Blue 7.0
2-naphthoic acid 6.9
3'-AMP 6.9
Daunomycin 6.9
SC-1 6.8
SC-1 6.8
10-formyltetrahydrofolate 6.7
Lincomycin 6.7
Lincomycin 6.6
Trimethylamine 6.5
MoSe2 6.3
MnO4 6.2
LY 294002 6.2
Nitrofurantoin 6.2
HMS 6.2
Toluidine blue 6.1
Nalidixic acid 6.1
Adenine 6.1
glucosamine-6-phosphate 6.0
perchloric acid 6.0
Chondroitin 6.0
Puromycin 5.9
Gliotoxin 5.8
DEAE 5.7
TES 5.7
Kanamycin 5.6
CTP 5.6
CDT 5.6
5-Azacytidine 5.6
Mannitol 5.6
Mannitol 5.5
Thymidine 5.5
ETH 5.4
Daunorubicin 5.4
dCTP 5.4
Mg2+ 5.4
dATP 5.3
Chlorophyll a 5.3
Guo 5.3
dGMP 5.3
Trypsin 5.3
Tetracycline 5.2
TTP 5.2
N-hydroxysuccinimide ester 5.2
UMP 5.2
T13 5.2
2-mercaptoethanol 5.2
Protamine 5.1
UTP 5.1
Lactose 5.1
MgCl2 5.1
Arsenite 5.1
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