Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.21.1 (DNase)
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Human Gene/Protein
C9orf146 12.0
DNase 12.0
deoxyribonuclease I-like 1 12.0
deoxyribonuclease I 12.0
DNASE1L2 11.3
deoxyribonuclease 11.2
acid DNase 11.1
DNase gamma 11.1
DNASE1 11.0
Non-histone chromosomal protein 11.0
-14 gene 11.0
DLAD 10.8
DNase X 10.6
Ubiquitin B 10.4
C20orf72 10.4
SEMA5B 10.4
Dist1 10.4
Erythroid transcription factor 10.4
TATDN1 10.4
DNASE1L3 10.4
deoxyribonuclease II 10.0
Nurim 10.0
RFT1 protein 10.0
nurim 10.0
DNASE1L1 10.0
DHP1 10.0
XAP-2 10.0
DFF35 9.9
Actin-like protein 9.7
TNFRSF1A-associated via death domain 9.7
A-kinase anchoring protein 95 9.7
K12 protein 9.7
DNase II 9.6
Caspase-activated DNase 9.5
Fanconi anemia, complementation group A 9.4
Nuclear factor 1 9.4
UDP-glucuronosyltransferase 1A7 9.4
AKR1B1 protein 9.4
Kruppel-type zinc finger protein 9.4
DNASE2 9.3
DFF40 9.3
ZK1 9.2
HTF9 9.2
CUX2 9.1
RPC3 9.0
putative exonuclease 9.0
FOX3 9.0
Mitochondrial DNA polymerase gamma 9.0
transducin-like enhancer of split 3 9.0
CHST12 9.0
SECTM1 9.0
PRBP 9.0
DFFB 9.0
caspase-activated DNase 8.9
ICAD 8.9
TMPRSS9 8.9
ENDOD1 8.9
ANKRD30A 8.9
B-ind1 8.7
INPP5A 8.7
ADCY7 8.6
TREX1 protein 8.6
PRDM13 8.4
SP82 8.4
Opalin 8.3
AP-2 gamma 8.3
death effector domain-containing 8.2
ATPase II 8.2
CDCA3 8.2
FCRL2 8.2
XIB 8.2
Nibrin 8.2
RNase 8.2
DNase I 8.2
Deoxyribonuclease II 8.1
heparan sulfate proteoglycan core protein 8.1
UCH-L5 8.1
Fc gamma receptor IIB 8.1
ITM2A 8.1
gag-pro-pol 8.0
more...
Disease
Rheumatic pneumonia 12.0
Acute cervical adenitis 11.0
Pleural infection 10.5
Voice alteration 9.4
Opportunistic mycoses 9.4
FHM3 8.3
viral leukemia 8.2
Acute viral bronchiolitis 8.0
North Carolina macular dystrophy 7.8
HS3 7.8
Mammary adenocarcinoma 7.7
Xeroderma 7.5
Transient myocardial ischemia 7.4
Glasser's disease 7.4
FHM2 7.2
AO2 7.1
KNS 6.8
Acute poststreptococcal glomerulonephritis 6.6
latent virus infection 6.6
throat infection 6.5
TDD 6.4
Sluder 6.4
streptococcal infection 6.4
Shope papilloma 6.3
Mitochondrial DNA depletion 6.3
Acute rheumatic fever 6.3
Streptococcus pyogenes infection 6.1
DHS 6.1
Myometrium 6.0
Parotid gland 6.0
DHS 6.0
XPG 6.0
acute glomerulonephritis 5.9
valvulitis 5.8
BMH 5.7
XPF 5.7
ATE 5.7
CDT 5.6
Pulmonary congestion 5.6
streptococcal pharyngitis 5.6
Cutaneous lupus erythematosus 5.5
chancroid 5.4
scarlet fever 5.4
cryptitis 5.4
myeloblastosis 5.4
rheumatic fever 5.3
acute bronchiolitis 5.3
DSH 5.3
African Burkitt's lymphoma 5.3
MPE 5.2
autoimmune vasculitis 5.1
pyoderma 5.1
viral carcinogenesis 5.1
Staphylococcus aureus endocarditis 4.9
crown gall 4.9
MWS 4.9
hereditary persistence of fetal hemoglobin 4.9
Aleutian disease 4.9
Rous sarcoma 4.9
Visna 4.8
BED 4.8
erysipelas 4.8
cystic fibrosis 4.7
Trichinella infection 4.7
lymphoblastoma 4.7
pharyngitis 4.7
vulvitis 4.7
NLS 4.7
GAN 4.7
xeroderma pigmentosum 4.7
hereditary ataxia 4.7
Legionella micdadei 4.7
Friend leukemia 4.6
avian sarcoma 4.6
metastatic osteosarcoma 4.6
Maedi 4.5
TTP 4.5
DBA2 4.5
carditis 4.4
oophoritis 4.4
more...
Symptom
autodigestion 5.7
nocturnal cough 5.2
Hudson 4.5
ACHE 4.1
No adverse effect 3.7
DNA marker 3.2
POA 3.0
adenitis 2.9
persistent cough 2.8
twitching 2.6
clubbing 2.2
cough 2.0
chorea 2.0
emaciation 2.0
muscle rigidity 1.9
agitation 1.8
starvation 1.7
Mills 1.7
sore throat 1.6
collapse 1.5
hemoptysis 1.4
acute abdominal pain 1.1
chronic cough 1.0
fever of unknown origin 1.0
stridor 0.8
wheezing 0.8
arthralgia 0.8
pallor 0.7
dyspnea 0.7
masculinization 0.7
dry eye 0.7
respiratory distress 0.6
knee pain 0.6
hepatomegaly 0.5
flushing 0.4
ophthalmoplegia 0.3
Ill 0.2
erythema -0.1
tremor -0.1
splenomegaly -0.2
shortness of breath -0.3
hyperoxia -0.3
diarrhea -0.3
cachexia -0.4
myalgia -0.7
functional recovery -0.7
exhaustion -0.7
anorexia -0.7
acidity -0.9
dystonia -1.0
chest pain -1.1
syncope -1.2
low back pain -1.3
angina -1.3
vomiting -1.4
thinning -1.4
hypothermia -2.1
discomfort -2.4
discomfort -2.6
seizures -2.7
pain -3.4
fatigue -3.6
headache -3.8
anesthesia -4.7
Drug
Pulmozyme 10.8
Cysteine hydrochloride 9.0
DNase I 8.2
Pronase 7.6
Lysostaphin 7.2
Nafcillin 7.0
Stelazine 6.7
naladixic acid 6.6
Sivelestat 6.4
Ddc 6.4
Arava 6.1
Esculin 6.0
Thrombostat 5.9
Tritiated water 5.8
Trifluoroethanol 5.8
Isopaque 5.7
Oxacillin 5.6
Compound 19 5.6
Atrovent 5.4
Sodium acetate 5.3
Marcaine 5.3
Neocarzinostatin 5.3
Alteplase 5.2
Deoxyadenosine 5.1
Alteplase 5.0
Alteplase 4.9
Pyridoxal phosphate 4.9
Gel 4.8
Hyaluronidase 4.8
AraC 4.8
Hyaluronidase 4.7
3-Methyladenine 4.6
EPL 4.6
SNL 4.5
ZnCl2 4.5
ZnCl2 4.5
CrCl3 4.5
CED 4.4
Mitomycin-C 4.3
Tween 60 4.3
Ipratropium bromide 4.3
balanced salt solution 4.2
Phosphatidylserine 4.2
Argatroban 4.2
Fraction 4.1
Ammonium chloride 4.1
Kaolin 4.1
Cibacron Blue 4.1
Miltefosine 4.1
Compound 9 4.0
Rasburicase 4.0
RAL 4.0
Photofrin II 4.0
FLP 3.9
KCL 3.9
ID2 3.9
CaCl2 3.8
CaCl2 3.8
CaCl2 3.7
NovoSeven 3.7
Ergosterol 3.7
Guanidine 3.6
Guanidine 3.6
PFA 3.6
Xylocaine 3.6
Filgrastim 3.6
Hypaque 3.5
Amiloride 3.5
Dextrose 3.4
Filgrastim 3.4
Hypaque 3.3
ampicillin 3.3
Rolipram 3.3
Amiloride 3.2
FeCl3 3.2
anti-RSV 3.2
Glutamic acid 3.0
Adriamycin 3.0
VCR 3.0
Paraffin 2.9
more...
Enzyme
DNase 12.0
deoxyribonuclease 11.7
deoxyribonuclease 11.7
yeast ribonuclease 11.4
DNase V 10.2
DNase II 10.0
exodeoxyribonuclease 9.6
endodeoxyribonuclease 8.9
L-fucose dehydrogenase 8.4
venom phosphodiesterase 8.3
micrococcal nuclease 8.1
exonuclease I 8.0
RNase 8.0
exonuclease V 7.9
lambda exonuclease 7.9
RNase 7.9
exonuclease VII 7.9
phosphoamidase 7.7
glycosulfatase 7.7
lysine decarboxylase 7.6
ribonuclease 7.5
ribonuclease 7.5
GPH 7.2
polynucleotide kinase 7.2
adenosine nucleosidase 7.2
3'-exonuclease 7.2
rubredoxin reductase 7.1
dCTPase 7.1
NAD glycohydrolase 6.9
C5a peptidase 6.8
hyaluronate lyase 6.7
nicotinamide adenine dinucleotide glycohydrolase 6.7
2',3'-cyclic nucleotide phosphohydrolase 6.6
caffeoyl-CoA O-methyltransferase 6.6
ScpA 6.6
rhizopuspepsin 6.6
violaxanthin de-epoxidase 6.5
peptidylarginine deiminase 6.5
lysostaphin 6.4
endonuclease 6.4
hyaluronidase 6.4
proteinase K 6.4
PGE2-9-ketoreductase 6.4
phospho-beta-glucosidase 6.3
uridine kinase 6.3
arginine deiminase 6.3
diacetyl reductase 6.2
caspase-10 6.1
caspase-10 6.1
hyaluronidase 6.1
nucleoside triphosphate phosphohydrolase 6.0
Tpt1 6.0
restriction-modification system 5.9
glucosamine-6-phosphate deaminase 5.9
homocitrate synthase 5.9
DNA polymerase 5.9
S1 nuclease 5.9
TSO 5.8
alginate lyase 5.8
endoproteinase Asp-N 5.8
D-serine dehydratase 5.8
beta-agarase 5.6
3'-phosphatase 5.6
chondroitinase 5.6
chondroitin ABC lyase 5.5
DNA ligase 5.5
DNA ligase 5.5
SpeB 5.5
adenine deaminase 5.4
RNase H 5.4
collagenase 5.3
poly(ADP-ribose) glycohydrolase 5.3
polyphosphatase 5.2
trypsin 5.2
AP lyase 5.2
lipase 5.1
Escherichia coli exonuclease III 5.1
sphingomyelin synthase 5.1
tyrosine aminotransferase 5.1
chondroitinase 5.1
more...
Compound
Dehydroheliotridine 11.0
4,5-dihydroxy-3-(1-naphthyldiazenyl)-2,7-naphthalenedisulfonic acid 11.0
1-Octanethiol 10.4
arsonoacetic acid 10.0
Streptovitacin A 9.4
Nitromin 9.0
Gallocyanin 8.7
Potassium acetate 8.7
Pyridoxamine 5'-phosphate 8.6
Cysteine hydrochloride 8.6
Methyl green 8.4
Versene 8.2
Neuraminic acid 8.0
Dracorhodin 8.0
Porfiromycin 8.0
RP 1 7.7
Nitrophenylphosphate 7.6
Promegestone 7.6
Stelazine 7.6
Cytochalasin E 7.3
Octopine 7.3
2,5-dihydroxyterephthalic acid 7.3
Picric acid 7.2
Tamibarotene 7.2
Echinomycin 7.1
1-phenylpiperazine 7.1
1-phenylpiperazine 7.1
Nafcillin 7.1
8-Hydroxyguanine 7.1
Dihydrostreptomycin 7.1
NMHE 6.9
DNAP 6.9
Cryptolepine 6.8
Cesium chloride 6.7
3,5-diaminobenzoic acid 6.7
1-methylpiperazine 6.7
Carboquone 6.7
Carboquone 6.7
Carboquone 6.7
Carboquone 6.7
Tolrestat 6.6
R 1881 6.6
Poly C 6.6
Normetanephrine 6.5
Nafoxidine 6.5
8-hydroxyguanosine 6.4
Phthalimide 6.4
Esculin 6.3
Chondroitin sulfate A 6.2
Phalloidin 6.2
Dithizone 6.1
Ethidium bromide 6.1
3'-AMP 6.1
Daunomycin 6.1
Deoxyribonucleic acid 6.1
Androsterone 6.1
Cholesterol sulfate 6.0
DPPD 6.0
Esculin 6.0
ICI 164384 6.0
deoxyribose-5-phosphate 6.0
4-phenylbutanoic acid 5.9
Cortexolone 5.9
16 alpha-hydroxyestrone 5.9
Atractyloside 5.9
Chromomycin A3 5.8
Trisodium phosphate 5.8
alpha-Amanitin 5.8
DMS 5.8
TIF 5.8
Distamycin A 5.8
TSO 5.8
CI-628 5.8
CI-628 5.8
Azure B 5.7
ASK 5.7
MPE 5.6
Oxacillin 5.6
3-aminobenzoic acid 5.6
CDT 5.6
more...