Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.21.1 (
DNase
)
7,655
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
DNase
4545
deoxyribonuclease
1188
RNase
699
Mol
662
DNase I
567
Sep
542
deoxyribonuclease I
519
endonuclease
382
histone
233
ATP
228
DNA polymerase
177
collagenase
172
polypeptide
162
lipase
155
SDS
150
thymus
135
Pseudomonas
133
Gen
109
hyaluronidase
93
phosphatase
92
lysozyme
90
ATPase
89
alkaline phosphatase
84
ADP
74
glycoprotein
72
amylase
71
collagen
70
DNaseI
68
caspase-3
66
catalase
62
nuclear protein
61
DNase II
60
myosin
57
fused
54
neuraminidase
52
lymphoid
50
Sp1
50
erythroid
49
AMP
48
NMR
46
phosphodiesterase
46
insulin
45
thymidine kinase
44
lipopolysaccharide
43
DNA polymerase alpha
43
tRNA
41
serum albumin
41
acid phosphatase
41
spermatozoa
40
acid DNase
39
RNA polymerase II
39
chymotrypsin
38
RNase A
38
beta-globin
38
pol
37
albumin
37
ribonucleoprotein
36
DNA-binding protein
36
GTP
34
ICAD
34
p53
34
interferon
34
cytokine
33
peroxidase
33
RNA polymerase I
32
ribonuclease A
32
IgA
32
estrogen receptor
32
AP-1
32
endoplasmic reticulum
31
ATAC
31
gut
31
esterase
30
beta-glucuronidase
29
phospholipase
29
mer
29
c-myc
29
NAD
28
cytochrome c
27
kit
27
RNase H
26
dimeric
26
telomeric
26
helicase
26
tissue plasminogen activator
26
gelsolin
25
thrombin
25
CAD
25
casein
25
DNA ligase
25
H2B
25
Bcl-2
25
Pol
24
membrane protein
24
neutrophil elastase
24
growth hormone
24
nov
23
CD4
23
Raji
22
caspase-activated DNase
22
API
22
IFN
22
DNA binding protein
22
RNP
22
alpha-amylase
22
histone H1
22
lectin
22
microsomal
21
myeloperoxidase
21
DNase gamma
21
glucocorticoid receptor
20
fibronectin
20
TLR9
20
hemoglobin
20
serine protease
20
cathepsin D
19
DNA polymerase beta
19
Chlamydomonas
19
PEG
19
histone H3
19
CAT
19
Rec
19
Poly
19
ACS
18
DFF40
18
transferrin
18
ornithine decarboxylase
18
chondroitinase
18
caspase-9
18
membrane-bound
18
tumor necrosis factor
18
mucin
17
dilute
17
CTCF
17
progesterone receptor
17
CTP
16
androgen receptor
16
poly(ADP-ribose) polymerase
16
glucosamine
16
TNF
16
DNASE1
16
CD8
16
LPS
16
DNA gyrase
16
Trypsin
16
beta-actin
16
Proteinase
15
PBS
15
lactate dehydrogenase
15
H2A
15
epidermal growth factor
15
SWI
15
TAT
15
threonine
15
superoxide dismutase
15
housekeeping
15
SOD
14
heavy chain
14
cofilin
14
Polymerase
14
more...
Disease
cancer
283
tumor
246
cystic fibrosis
162
SDS
150
systemic lupus erythematosus
141
carcinoma
101
Epstein
84
herpes simplex
81
leukemia
68
hepatocellular carcinoma
67
breast cancer
49
cold
45
plaque
44
HIV
43
immunodeficiency
42
lupus
36
melanoma
35
infectious diseases
35
lupus
35
lung disease
35
carcinogenesis
34
sepsis
33
Mycobacterium
31
vaccinia
30
rheumatoid arthritis
30
MCF
30
arthritis
30
Mycoplasma
29
coronary artery disease
28
lymphoma
27
sarcoma
26
Klebsiella
25
pneumonia
25
sepsis
25
streptococcal infection
25
virus infection
24
hepatitis B
24
cholera
24
Infection
22
rheumatic fever
22
Haemophilus
22
Rous sarcoma
21
lupus nephritis
21
adenocarcinoma
20
SLE
20
empyema
20
tumorigenesis
20
erythroleukemia
19
tumor growth
19
autoimmune disease
19
prostate cancer
18
xeroderma pigmentosum
18
ischemia
18
asthma
18
renal disease
17
influenza
17
nephritis
17
neuroblastoma
17
uterus
17
cytomegalovirus
17
lung cancer
17
mastitis
16
diabetes
16
glomerulonephritis
16
proteinuria
15
multiple myeloma
15
Alzheimer's disease
15
pharyngitis
15
toxic shock syndrome
15
Proteus
14
SEM
14
tuberculosis
14
AIDS
14
metastases
14
mammary tumor
13
multiple sclerosis
13
TEM
13
TEM
12
tumor progression
12
depression
12
mole
11
bacterial infection
11
DBA
11
hepatitis C
11
mole
11
hepatitis
11
Burkitt's lymphoma
11
Adenovirus
11
heart failure
11
bronchiectasis
11
gastric cancer
10
hypertension
10
chancroid
10
GSH
10
fasciitis
10
epididymis
10
myeloblastosis
10
PHA
10
stroke
10
fits
9
malaria
9
herpes
9
squamous cell carcinoma
9
acute glomerulonephritis
9
pancreatic cancer
9
Pleural infection
9
acute lymphoblastic leukemia
9
HS3
9
bronchiolitis
9
Leukemia
9
vasculitis
8
fungal infection
8
glioma
8
respiratory failure
8
embryonal carcinoma
8
osteosarcoma
8
anemia
8
PAM
8
TTP
8
Dissociation
8
choriocarcinoma
8
scleroderma
8
ATM
8
TTP
8
cellulitis
7
DHS
7
myocardial infarction
7
pheochromocytoma
7
streptococcal pharyngitis
7
psoriasis
7
DHS
7
suicide
7
pancreatitis
7
Conn
7
XPF
7
acute myocardial infarction
7
atherosclerosis
7
myocardial ischemia
7
worms
7
colorectal cancer
7
Shigella
7
cirrhosis
7
chronic obstructive pulmonary disease
7
primary biliary cirrhosis
7
pyoderma
7
periodontitis
7
B-cell lymphoma
7
gonococcal
7
XPG
7
Sarcoma
6
EBV infection
6
Sarcoma
6
skin infection
6
glioblastoma
6
chronic pancreatitis
6
scarlet fever
6
Kaposi's sarcoma
6
PCC
6
cardiovascular disease
6
fibrosarcoma
6
more...
Symptom
cough
23
starvation
20
collapse
19
diarrhea
11
dyspnea
11
agitation
10
respiratory distress
7
pain
6
Hudson
6
tremor
4
hemoptysis
4
autodigestion
4
arthralgia
3
twitching
3
seizures
3
erythema
3
Ill
3
vomiting
3
exhaustion
2
chest pain
2
chorea
2
splenomegaly
2
sore throat
2
anorexia
2
acidity
2
DNA marker
2
hepatomegaly
2
angina
2
flushing
2
wheezing
2
functional recovery
2
discomfort
1
muscle rigidity
1
myalgia
1
hypothermia
1
ACHE
1
No adverse effect
1
anesthesia
1
ophthalmoplegia
1
shortness of breath
1
chronic cough
1
Mills
1
hyperoxia
1
thinning
1
discomfort
1
POA
1
clubbing
1
acute abdominal pain
1
dry eye
1
low back pain
1
nocturnal cough
1
dystonia
1
masculinization
1
persistent cough
1
emaciation
1
cachexia
1
pallor
1
stridor
1
fatigue
1
headache
1
adenitis
1
fever of unknown origin
1
syncope
1
knee pain
1
Drug
DNase I
600
Gel
102
lysine
89
Pronase
59
ampicillin
40
Dermatol
27
lactose
26
CaCl2
21
CaCl2
21
CaCl2
21
Pulmozyme
17
Asn
14
ABC
14
IL-2
14
NADH
13
ascorbate
11
Fraction
11
ROS
10
Adriamycin
9
Nephron
8
Leaf
8
IFN-gamma
7
ZnCl2
7
balanced salt solution
7
MAP
7
AraC
7
ZnCl2
7
Mutagen
6
CSF
5
Growth hormone
5
Growth hormone
5
ETS
4
Retinoic acid
4
citric acid
4
Asthma
4
Amiloride
4
Fluorescein
4
EE2
4
FLP
4
TAT
4
Paraffin
4
Fluorescein
4
Amiloride
4
Ethanol
3
Phosphatidylserine
3
Glutathione
3
Albumin
3
Biopolymers
3
FeCl3
3
caffeine
3
Glycerol
3
CTX
3
VCR
3
Hyaluronidase
3
Oxacillin
3
CED
3
Hypaque
3
Ringer's solution
3
nitroglycerin
3
PFA
3
Alanine
3
Hyaluronidase
3
Lysostaphin
3
Hypaque
3
ENT
3
CTX
2
Bifidobacterium
2
Ddc
2
CTX
2
MOF
2
NAG
2
Check
2
Isopaque
2
Itraconazole
2
G418
2
Lactose
2
NH3
2
-deoxyadenosine
2
Alteplase
2
PCP
2
Cibacron Blue
2
Alteplase
2
DHT
2
Alteplase
2
Histamine
2
Nafcillin
2
Monit
2
HCH
2
PTH
2
DHT
2
ROC
2
IPM
2
Cardiovasc
1
GEO
1
NBT
1
Triclosan
1
Etoposide
1
CDP
1
NovoSeven
1
AGG
1
Rolipram
1
Atrovent
1
Xylocaine
1
Ofloxacin
1
Thrombostat
1
AZT
1
Vitamin K
1
Guanidine
1
Salbutamol
1
DMI
1
Vitamin B
1
Streptokinase
1
SNL
1
Ergosterol
1
uPA
1
Dextrose
1
Ceftazidime
1
Arava
1
ADR
1
Cysteine hydrochloride
1
Gelatin
1
Sodium acetate
1
Adenosine deaminase
1
Bupivacaine
1
AMC
1
Rasburicase
1
Pyridoxal phosphate
1
Ipratropium bromide
1
ZnO
1
Glutamic acid
1
Angiotensin II
1
Ranitidine
1
Arsenic trioxide
1
Galactose
1
TES
1
SiO2
1
Kenyan
1
Filgrastim
1
Alliance
1
CTA
1
Indomethacin
1
Miltefosine
1
Allergen
1
Compound 9
1
RAL
1
Serum albumin
1
Silica
1
pyridoxal phosphate
1
Dial
1
ID2
1
Argatroban
1
VCR
1
Compound 19
1
Ammonium chloride
1
Metrizamide
1
Neocarzinostatin
1
Trifluoroethanol
1
Kaolin
1
Rutin
1
Guanidine
1
more...
Enzyme
DNase
7655
deoxyribonuclease
1195
deoxyribonuclease
1194
RNase
1017
RNase
982
endonuclease
383
trypsin
370
ribonuclease
289
ribonuclease
289
DNA polymerase
239
RNA polymerase
211
micrococcal nuclease
181
collagenase
177
lipase
158
DNase II
107
reverse transcriptase
102
ATPase
101
alkaline phosphatase
99
hyaluronidase
99
hyaluronidase
93
lysozyme
92
proteinase K
82
catalase
81
luciferase
71
phosphodiesterase
68
peroxidase
62
acid phosphatase
56
neuraminidase
56
S1 nuclease
51
elastase
50
caspase-3
49
chymotrypsin
46
beta-galactosidase
44
thymidine kinase
44
chloramphenicol acetyltransferase
38
topoisomerase
37
protein kinase
37
phospholipase C
35
urease
34
urease
34
venom phosphodiesterase
34
tissue plasminogen activator
34
beta-lactamase
33
topoisomerase
30
DNA ligase
30
DNA ligase
30
pepsin
29
ERK
28
beta-glucuronidase
28
RNase H
27
thrombin
25
CAD
25
CAD
25
CAD
25
polynucleotide kinase
24
neutrophil elastase
23
chondroitinase
23
PARP
22
ornithine decarboxylase
22
alpha-amylase
22
papain
21
lactate dehydrogenase
20
cathepsin D
19
lysine decarboxylase
19
plasmin
19
ACS
18
chondroitinase
18
transcriptase
17
endodeoxyribonuclease
16
DNA methyltransferase
16
protein kinase C
16
phospholipase A2
16
arginine deiminase
16
caspase-9
16
glutathione S-transferase
15
superoxide dismutase
15
cellulase
15
3'-exonuclease
14
chitinase
14
exonuclease I
14
beta-glucosidase
14
beta-glucosidase
13
NAD glycohydrolase
12
glyceraldehyde-3-phosphate dehydrogenase
12
subtilisin
12
5'-nucleotidase
12
lambda exonuclease
12
tyrosine aminotransferase
11
calcineurin
11
ricin
10
lysostaphin
10
glyceraldehyde-3-phosphate dehydrogenase
10
glyceraldehyde-3-phosphate dehydrogenase
9
NADPH oxidase
9
glyceraldehyde-3-phosphate dehydrogenase
9
NADPH oxidase
9
glyceraldehyde-3-phosphate dehydrogenase
9
focal adhesion kinase
8
ADP-ribosyltransferase
8
cytochrome oxidase
8
hyaluronate lyase
8
peptidylarginine deiminase
8
caspase-8
8
PAM
8
aldolase
8
triphosphatase
7
ADP-ribosyltransferase
7
RNase III
7
xylanase
7
mitogen-activated protein kinase
7
succinate dehydrogenase
7
xylanase
7
TSP-1
7
nucleotidase
7
pectinase
7
tyrosinase
7
phosphoenolpyruvate carboxykinase
6
phosphoenolpyruvate carboxykinase
6
phosphoenolpyruvate carboxykinase
6
cathepsin G
6
sulfatase
6
heparinase
6
ribonucleotide reductase
6
ribonucleotide reductase
6
pyruvate kinase
6
urokinase-type plasminogen activator
6
proteasome
6
monoamine oxidase
5
PAL
5
IMP dehydrogenase
5
deaminase
5
RNase T1
5
adenylate cyclase
5
malate dehydrogenase
5
ceruloplasmin
5
carbonic anhydrase
5
lysin
5
aspartate aminotransferase
5
firefly luciferase
5
renin
5
glucose-6-phosphatase
5
phospholipase D
5
exodeoxyribonuclease
5
carboxypeptidase A
5
exonuclease V
5
alginate lyase
5
restriction-modification system
5
GAS
5
hexokinase
4
CD10
4
caspase-1
4
ScpA
4
arylsulfatase
4
thermolysin
4
hexosaminidase
4
RNA ligase
4
alanine aminotransferase
4
glutathione peroxidase
4
glucose-6-phosphate dehydrogenase
4
complex I
4
more...
Compound
DNA
3979
Dec
529
sodium
307
calcium
271
Clin
259
salt
255
sulfate
242
Mg2+
236
ATP
228
phosphate
212
SDS
164
water
162
EDTA
138
EDTA
137
DEAE
131
bromide
105
lysine
103
Triton X-100
102
manganese
99
ammonium
98
glucose
96
acetate
93
urea
87
oxygen
84
zinc
80
arginine
80
ADP
79
phenol
78
His
76
ADP
74
ADP
74
ethanol
72
cAMP
64
hydrogen
61
PEG
61
alanine
59
methionine
58
galactose
57
glycerol
55
AMP
54
serine
53
MgCl2
51
leucine
50
uridine
49
pyrimidine
47
pyrimidine
47
HCl
44
cysteine
43
potassium
43
nitrogen
43
formaldehyde
43
Asp
43
chloroform
43
acrylamide
42
iron
40
acridine
40
silver
39
copper
37
Guo
36
formaldehyde
36
NAD
36
tryptophan
35
Tris
35
GTP
35
nitrate
34
PEG
34
TCA
33
NH2
32
cobalt
32
UTP
31
tyrosine
31
xylose
30
guanidine
30
ADP-ribose
30
Tris
29
threonine
29
NAD
28
dUTP
27
Optimal
26
tryptophan
26
hyaluronic acid
25
tryptophan
25
tryptophan
25
TTP
24
Gly
24
acetone
24
proline
24
CAT
24
nickel
23
nicotinamide
23
Phe
23
iodine
23
2-mercaptoethanol
23
COS
22
CaCl2
21
Triton
21
DMS
21
methanol
21
Sucrose
20
CAT
19
glutamic acid
19
CAT
19
phosphorus
18
ACS
18
PEI
18
perchloric acid
18
PEI
18
dATP
18
ACS
18
PAM
17
retinoic acid
17
PAM
17
CTP
16
sodium chloride
16
Trypsin
16
CAM
16
H2S
16
TNF
16
TEM
16
aspartic acid
14
aspartic acid
14
aspartic acid
14
aspartic acid
14
Histone
13
Tween 80
13
aluminum
13
DMSO
13
GlcNAc
13
adenylate
13
NADH
13
N-acetylcysteine
12
BCG
12
formamide
12
CO2
12
DBA
12
MTT
12
H2S
12
GSH
11
Salt
11
TPA
11
Methicillin
11
TPA
11
MIC
11
GSH
11
DBA
11
PMA
11
DBA
11
dCTP
11
cadmium
11
PMA
10
H2O2
10
Deoxyribonucleic acid
10
Adriamycin
10
TOF
10
hydroxide
10
pyrene
10
Ile
9
mercury
9
Heparin
9
methyl methanesulfonate
9
more...