Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.8 (cholinesterase)
12,691 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
acetylcholinesterase 3650
butyrylcholinesterase 3588
Sep 871
AChE 628
pseudocholinesterase 495
esterase 393
Cholinesterase 389
albumin 327
Mol 324
alkaline phosphatase 279
carboxylesterase 225
catalase 213
amyloid precursor protein 201
choline acetyltransferase 185
lactate dehydrogenase 180
muscarinic receptor 180
NMR 179
aspartate aminotransferase 160
superoxide dismutase 158
alanine aminotransferase 151
serum albumin 150
amylase 137
hemoglobin 124
glucosidase 118
tyrosinase 118
GSH 118
paraoxonase 111
insulin 91
ATPase 91
glutathione S-transferase 89
acetylcholine receptor 88
prothrombin 87
CA1 87
axonal 82
acid phosphatase 82
nicotinic acetylcholine receptor 79
microsomal 76
NMDA receptor 71
BACE1 68
cytochrome P450 66
arylesterase 65
glutathione peroxidase 64
creatine kinase 62
peroxidase 60
lipase 58
MAO-B 55
collagen 55
amyloid beta 54
TNF 53
GABA 52
membrane-bound 52
FRAP 51
endoplasmic reticulum 51
transferrin 51
Gen 50
carbonic anhydrase 47
lipoxygenase 46
ESI 45
5-hydroxytryptamine 44
ADAS 44
caspase-3 43
AST 43
ATP 43
serum protein 43
gut 43
apolipoprotein E 42
Carboxylesterase 42
MAO-A 41
LDH 41
GPT 41
SDS 40
neuropathy target esterase 40
Pol 38
gamma-glutamyltransferase 38
thymus 37
substance P 37
She 36
cytokine 36
glycoprotein 35
MRI 35
more...
Disease
Alzheimer's disease 2286
dementia 792
depression 329
cognitive impairment 313
Parkinson's disease 191
cirrhosis 178
myasthenia gravis 162
cancer 141
diabetes 139
GSH 118
fits 108
memory impairment 105
psychosis 90
neuroblastoma 90
tumor 88
hallucinations 87
liver disease 72
amnesia 67
plaque 66
hypertension 65
obesity 59
Dementia with Lewy bodies 57
hepatocellular carcinoma 57
neuropathy 49
parkinsonism 48
malnutrition 47
stroke 47
Evans 46
respiratory failure 43
chronic hepatitis 41
schizophrenia 41
SDS 40
delusions 39
myasthenia 39
cold 38
ischemia 38
epilepsy 36
SEM 36
delirium 35
anemia 34
hepatitis 34
glaucoma 33
hyperglycemia 33
cognitive deficit 32
suicide 32
type 2 diabetes 32
coma 31
fatty liver 30
carcinoma 30
Huntington's disease 29
senile dementia 29
cocaine abuse 27
cardiovascular disease 26
autoimmune disease 26
varices 25
PAM 25
Down syndrome 24
chronic liver disease 24
addiction 23
hyperlipidemia 23
worms 23
malaria 22
cholestasis 22
leukemia 22
HIV 22
multiple sclerosis 22
aggression 21
asthma 21
SAR 21
sepsis 20
sepsis 20
prolapse 20
heart failure 20
West 19
hepatitis B 19
thymoma 18
SCH 18
cocaine addiction 18
atherosclerosis 18
hypothyroidism 17
more...
Symptom
anesthesia 215
weakness 133
seizures 132
pain 66
diarrhea 65
agitation 62
vomiting 58
tremor 54
nausea 52
memory loss 50
headache 47
fatigue 45
hypothermia 41
ataxia 37
apathy 32
dizziness 30
analgesia 26
ACHE 24
respiratory distress 23
fasciculation 23
dyspnea 20
anorexia 20
exhaustion 18
sleepiness 17
nausea and vomiting 15
overweight 14
abdominal pain 14
functional recovery 13
syncope 13
cough 13
collapse 12
visual hallucination 11
blurred vision 11
insomnia 11
acute stress 10
constipation 10
twitching 9
skin irritation 9
lethargy 9
splenomegaly 8
dystonia 8
myalgia 8
rhinorrhea 8
paresis 8
discomfort 7
hepatomegaly 7
flushing 7
erythema 7
bradykinesia 6
hypoproteinemia 6
Ill 6
incoordination 6
thinning 6
spasm 6
spasticity 6
paresthesia 6
ophthalmoplegia 6
vertigo 5
discomfort 5
hypercapnia 5
starvation 5
muscle cramps 5
asthenia 5
abdominal cramps 4
hypotonia 4
epigastric pain 4
chest pain 4
acidity 4
emaciation 3
Behavioral symptoms 3
consciousness disturbance 3
despair 3
chills 3
ENT 3
chest tightness 3
cyanosis 3
frequent urination 3
Decreased activity 3
arthralgia 3
tachypnea 3
more...
Drug
Donepezil 149
Atropine 100
DFP 90
vitamin E 61
THA 58
Scopolamine 37
CSF 32
lysine 28
Aricept 27
Monit 24
Pyridostigmine bromide 23
ascorbate 22
ROS 21
EDR 20
Albumin 17
Pralidoxime 16
EPA 16
Pyridostigmine bromide 16
NADH 15
Nephron 15
caffeine 15
Vitamin E 14
Exelon 14
Galanthamine 14
Dermatol 13
CTX 13
Serum albumin 12
Gel 12
Leaf 12
Exelon 12
Glutathione 10
Distigmine bromide 10
citric acid 9
Clonidine 9
Mestinon 9
Cardiovasc 9
Ethanol 8
PCP 8
Pilocarpine 8
CPT-11 8
Reminyl 8
TAK 8
Spectrum 7
Mutagen 7
lactose 7
ROC 7
Rocuronium 7
Ringer's solution 6
EE2 6
Fraction 6
Cognex 5
Azilect 5
ENT 5
ALA 5
Diphenhydramine 5
p75 5
PTC 4
Forskolin 4
ampicillin 4
niacin 4
Brij 96 4
Ginseng 4
9-THC 4
CaCl2 4
Ranitidine 4
Namenda 4
Prednisone 4
Reserpine 4
DMAA 4
CaCl2 4
CaCl2 4
Piracetam 4
Histamine 4
HCH 4
MRC 4
BTC 4
Pronase 3
Thyroglobulin 3
Fluorescein 3
Glycyrrhiza 3
more...
Enzyme
cholinesterase 12691
acetylcholinesterase 11108
alkaline phosphatase 281
carboxylesterase 267
alanine aminotransferase 250
catalase 222
aspartate aminotransferase 205
lactate dehydrogenase 201
choline acetyltransferase 192
superoxide dismutase 184
monoamine oxidase 163
paraoxonase 142
paraoxonase 126
gamma-glutamyl transpeptidase 119
tyrosinase 118
ATPase 116
glutathione S-transferase 111
peroxidase 92
acid phosphatase 83
creatine kinase 80
glutathione peroxidase 65
lipase 65
trypsin 59
carbonic anhydrase 50
lipoxygenase 46
neuropathy target esterase 43
AST 42
succinate dehydrogenase 41
glutamate dehydrogenase 34
glutamate dehydrogenase 34
glutamate dehydrogenase 34
choline oxidase 33
deaminase 33
chymotrypsin 33
leucine aminopeptidase 31
adenosine deaminase 31
adenosine deaminase 31
ACS 30
caspase-3 30
glucose-6-phosphate dehydrogenase 30
glutathione reductase 29
urease 28
urease 28
protein kinase C 27
protein kinase 27
pepsin 27
mitogen-activated protein kinase 27
aldolase 26
PAM 25
succinic dehydrogenase 25
alpha-amylase 25
ERK 25
malate dehydrogenase 23
cytochrome oxidase 21
collagenase 20
diaphorase 19
beta-secretase 19
ceruloplasmin 19
ACE 19
tyrosine hydroxylase 18
CYP3A4 17
phosphorylase 17
phosphodiesterase 17
prolyl endopeptidase 17
beta-glucuronidase 16
sorbitol dehydrogenase 16
cholesterol esterase 16
GSK 15
phospholipase C 15
demethylase 14
glucose-6-phosphatase 14
thrombin 14
NADPH-diaphorase 13
5'-nucleotidase 13
monoacylglycerol lipase 13
isocitrate dehydrogenase 13
aspirin esterase 12
NQO1 12
arginase 12
phospholipase A2 10
more...
Compound
Dec 848
water 637
Clin 588
phosphate 264
glucose 258
sodium 246
calcium 244
DNA 244
ACh 226
oxygen 213
serine 169
urea 161
hydrogen 156
galanthamine 153
bromide 147
DPPH 147
acetate 146
nitrogen 145
glutamate 144
creatinine 139
methanol 134
iodine 129
GSH 128
GSH 128
PAM 124
potassium 123
OMPA 121
Physostigmine 119
sulfate 112
ethanol 110
ethyl acetate 109
Rivastigmine 101
Atropine 100
nitric oxide 98
Tacrine 98
salt 91
silver 90
ammonium 87
iron 86
His 84
Chlorpyrifos 84
phosphorus 83
DDVP 82
noradrenaline 80
pyridine 78
zinc 74
copper 74
tyrosine 73
galactose 69
alanine 63
hexane 62
5-HT 62
arginine 61
NMDA 60
Triton X-100 57
phenol 56
GABA 55
Gly 55
TNF 53
piperidine 53
piperidine 53
chloroform 52
GABA 52
DEP 51
Neostigmine 48
Soman 48
Pyridostigmine 47
Mivacurium 43
ATP 43
Succinylcholine 43
SDS 42
Diazinon 42
cadmium 42
GPT 41
leucine 41
Memantine 41
mercury 40
4-nitrophenyl 39
Asp 38
dichloromethane 37
more...