Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.8 (
cholinesterase
)
12,691
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
acetylcholinesterase
3650
butyrylcholinesterase
3588
Sep
871
AChE
628
pseudocholinesterase
495
esterase
393
Cholinesterase
389
albumin
327
Mol
324
alkaline phosphatase
279
carboxylesterase
225
catalase
213
amyloid precursor protein
201
choline acetyltransferase
185
lactate dehydrogenase
180
muscarinic receptor
180
NMR
179
aspartate aminotransferase
160
superoxide dismutase
158
alanine aminotransferase
151
serum albumin
150
amylase
137
hemoglobin
124
glucosidase
118
tyrosinase
118
GSH
118
paraoxonase
111
insulin
91
ATPase
91
glutathione S-transferase
89
acetylcholine receptor
88
prothrombin
87
CA1
87
axonal
82
acid phosphatase
82
nicotinic acetylcholine receptor
79
microsomal
76
NMDA receptor
71
BACE1
68
cytochrome P450
66
arylesterase
65
glutathione peroxidase
64
creatine kinase
62
peroxidase
60
lipase
58
MAO-B
55
collagen
55
amyloid beta
54
TNF
53
GABA
52
membrane-bound
52
FRAP
51
endoplasmic reticulum
51
transferrin
51
Gen
50
carbonic anhydrase
47
lipoxygenase
46
ESI
45
5-hydroxytryptamine
44
ADAS
44
caspase-3
43
AST
43
ATP
43
serum protein
43
gut
43
apolipoprotein E
42
Carboxylesterase
42
MAO-A
41
LDH
41
GPT
41
SDS
40
neuropathy target esterase
40
Pol
38
gamma-glutamyltransferase
38
thymus
37
substance P
37
She
36
cytokine
36
glycoprotein
35
MRI
35
more...
Disease
Alzheimer's disease
2286
dementia
792
depression
329
cognitive impairment
313
Parkinson's disease
191
cirrhosis
178
myasthenia gravis
162
cancer
141
diabetes
139
GSH
118
fits
108
memory impairment
105
psychosis
90
neuroblastoma
90
tumor
88
hallucinations
87
liver disease
72
amnesia
67
plaque
66
hypertension
65
obesity
59
Dementia with Lewy bodies
57
hepatocellular carcinoma
57
neuropathy
49
parkinsonism
48
malnutrition
47
stroke
47
Evans
46
respiratory failure
43
chronic hepatitis
41
schizophrenia
41
SDS
40
delusions
39
myasthenia
39
cold
38
ischemia
38
epilepsy
36
SEM
36
delirium
35
anemia
34
hepatitis
34
glaucoma
33
hyperglycemia
33
cognitive deficit
32
suicide
32
type 2 diabetes
32
coma
31
fatty liver
30
carcinoma
30
Huntington's disease
29
senile dementia
29
cocaine abuse
27
cardiovascular disease
26
autoimmune disease
26
varices
25
PAM
25
Down syndrome
24
chronic liver disease
24
addiction
23
hyperlipidemia
23
worms
23
malaria
22
cholestasis
22
leukemia
22
HIV
22
multiple sclerosis
22
aggression
21
asthma
21
SAR
21
sepsis
20
sepsis
20
prolapse
20
heart failure
20
West
19
hepatitis B
19
thymoma
18
SCH
18
cocaine addiction
18
atherosclerosis
18
hypothyroidism
17
more...
Symptom
anesthesia
215
weakness
133
seizures
132
pain
66
diarrhea
65
agitation
62
vomiting
58
tremor
54
nausea
52
memory loss
50
headache
47
fatigue
45
hypothermia
41
ataxia
37
apathy
32
dizziness
30
analgesia
26
ACHE
24
respiratory distress
23
fasciculation
23
dyspnea
20
anorexia
20
exhaustion
18
sleepiness
17
nausea and vomiting
15
overweight
14
abdominal pain
14
functional recovery
13
syncope
13
cough
13
collapse
12
visual hallucination
11
blurred vision
11
insomnia
11
acute stress
10
constipation
10
twitching
9
skin irritation
9
lethargy
9
splenomegaly
8
dystonia
8
myalgia
8
rhinorrhea
8
paresis
8
discomfort
7
hepatomegaly
7
flushing
7
erythema
7
bradykinesia
6
hypoproteinemia
6
Ill
6
incoordination
6
thinning
6
spasm
6
spasticity
6
paresthesia
6
ophthalmoplegia
6
vertigo
5
discomfort
5
hypercapnia
5
starvation
5
muscle cramps
5
asthenia
5
abdominal cramps
4
hypotonia
4
epigastric pain
4
chest pain
4
acidity
4
emaciation
3
Behavioral symptoms
3
consciousness disturbance
3
despair
3
chills
3
ENT
3
chest tightness
3
cyanosis
3
frequent urination
3
Decreased activity
3
arthralgia
3
tachypnea
3
more...
Drug
Donepezil
149
Atropine
100
DFP
90
vitamin E
61
THA
58
Scopolamine
37
CSF
32
lysine
28
Aricept
27
Monit
24
Pyridostigmine bromide
23
ascorbate
22
ROS
21
EDR
20
Albumin
17
Pralidoxime
16
EPA
16
Pyridostigmine bromide
16
NADH
15
Nephron
15
caffeine
15
Vitamin E
14
Exelon
14
Galanthamine
14
Dermatol
13
CTX
13
Serum albumin
12
Gel
12
Leaf
12
Exelon
12
Glutathione
10
Distigmine bromide
10
citric acid
9
Clonidine
9
Mestinon
9
Cardiovasc
9
Ethanol
8
PCP
8
Pilocarpine
8
CPT-11
8
Reminyl
8
TAK
8
Spectrum
7
Mutagen
7
lactose
7
ROC
7
Rocuronium
7
Ringer's solution
6
EE2
6
Fraction
6
Cognex
5
Azilect
5
ENT
5
ALA
5
Diphenhydramine
5
p75
5
PTC
4
Forskolin
4
ampicillin
4
niacin
4
Brij 96
4
Ginseng
4
9-THC
4
CaCl2
4
Ranitidine
4
Namenda
4
Prednisone
4
Reserpine
4
DMAA
4
CaCl2
4
CaCl2
4
Piracetam
4
Histamine
4
HCH
4
MRC
4
BTC
4
Pronase
3
Thyroglobulin
3
Fluorescein
3
Glycyrrhiza
3
more...
Enzyme
cholinesterase
12691
acetylcholinesterase
11108
alkaline phosphatase
281
carboxylesterase
267
alanine aminotransferase
250
catalase
222
aspartate aminotransferase
205
lactate dehydrogenase
201
choline acetyltransferase
192
superoxide dismutase
184
monoamine oxidase
163
paraoxonase
142
paraoxonase
126
gamma-glutamyl transpeptidase
119
tyrosinase
118
ATPase
116
glutathione S-transferase
111
peroxidase
92
acid phosphatase
83
creatine kinase
80
glutathione peroxidase
65
lipase
65
trypsin
59
carbonic anhydrase
50
lipoxygenase
46
neuropathy target esterase
43
AST
42
succinate dehydrogenase
41
glutamate dehydrogenase
34
glutamate dehydrogenase
34
glutamate dehydrogenase
34
choline oxidase
33
deaminase
33
chymotrypsin
33
leucine aminopeptidase
31
adenosine deaminase
31
adenosine deaminase
31
ACS
30
caspase-3
30
glucose-6-phosphate dehydrogenase
30
glutathione reductase
29
urease
28
urease
28
protein kinase C
27
protein kinase
27
pepsin
27
mitogen-activated protein kinase
27
aldolase
26
PAM
25
succinic dehydrogenase
25
alpha-amylase
25
ERK
25
malate dehydrogenase
23
cytochrome oxidase
21
collagenase
20
diaphorase
19
beta-secretase
19
ceruloplasmin
19
ACE
19
tyrosine hydroxylase
18
CYP3A4
17
phosphorylase
17
phosphodiesterase
17
prolyl endopeptidase
17
beta-glucuronidase
16
sorbitol dehydrogenase
16
cholesterol esterase
16
GSK
15
phospholipase C
15
demethylase
14
glucose-6-phosphatase
14
thrombin
14
NADPH-diaphorase
13
5'-nucleotidase
13
monoacylglycerol lipase
13
isocitrate dehydrogenase
13
aspirin esterase
12
NQO1
12
arginase
12
phospholipase A2
10
more...
Compound
Dec
848
water
637
Clin
588
phosphate
264
glucose
258
sodium
246
calcium
244
DNA
244
ACh
226
oxygen
213
serine
169
urea
161
hydrogen
156
galanthamine
153
bromide
147
DPPH
147
acetate
146
nitrogen
145
glutamate
144
creatinine
139
methanol
134
iodine
129
GSH
128
GSH
128
PAM
124
potassium
123
OMPA
121
Physostigmine
119
sulfate
112
ethanol
110
ethyl acetate
109
Rivastigmine
101
Atropine
100
nitric oxide
98
Tacrine
98
salt
91
silver
90
ammonium
87
iron
86
His
84
Chlorpyrifos
84
phosphorus
83
DDVP
82
noradrenaline
80
pyridine
78
zinc
74
copper
74
tyrosine
73
galactose
69
alanine
63
hexane
62
5-HT
62
arginine
61
NMDA
60
Triton X-100
57
phenol
56
GABA
55
Gly
55
TNF
53
piperidine
53
piperidine
53
chloroform
52
GABA
52
DEP
51
Neostigmine
48
Soman
48
Pyridostigmine
47
Mivacurium
43
ATP
43
Succinylcholine
43
SDS
42
Diazinon
42
cadmium
42
GPT
41
leucine
41
Memantine
41
mercury
40
4-nitrophenyl
39
Asp
38
dichloromethane
37
more...