Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.8 (
cholinesterase
)
12,691
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
acetylcholinesterase
3650
butyrylcholinesterase
3588
Sep
871
AChE
628
pseudocholinesterase
495
esterase
393
Cholinesterase
389
albumin
327
Mol
324
alkaline phosphatase
279
carboxylesterase
225
catalase
213
amyloid precursor protein
201
choline acetyltransferase
185
lactate dehydrogenase
180
muscarinic receptor
180
NMR
179
aspartate aminotransferase
160
superoxide dismutase
158
alanine aminotransferase
151
serum albumin
150
amylase
137
hemoglobin
124
tyrosinase
118
GSH
118
glucosidase
118
paraoxonase
111
insulin
91
ATPase
91
glutathione S-transferase
89
acetylcholine receptor
88
CA1
87
prothrombin
87
acid phosphatase
82
axonal
82
nicotinic acetylcholine receptor
79
microsomal
76
NMDA receptor
71
BACE1
68
cytochrome P450
66
more...
Disease
Alzheimer's disease
2286
dementia
792
depression
329
cognitive impairment
313
Parkinson's disease
191
cirrhosis
178
myasthenia gravis
162
cancer
141
diabetes
139
GSH
118
fits
108
memory impairment
105
neuroblastoma
90
psychosis
90
tumor
88
hallucinations
87
liver disease
72
amnesia
67
plaque
66
hypertension
65
obesity
59
Dementia with Lewy bodies
57
hepatocellular carcinoma
57
neuropathy
49
parkinsonism
48
malnutrition
47
stroke
47
Evans
46
respiratory failure
43
schizophrenia
41
chronic hepatitis
41
SDS
40
delusions
39
myasthenia
39
ischemia
38
cold
38
SEM
36
epilepsy
36
delirium
35
hepatitis
34
more...
Symptom
anesthesia
215
weakness
133
seizures
132
pain
66
diarrhea
65
agitation
62
vomiting
58
tremor
54
nausea
52
memory loss
50
headache
47
fatigue
45
hypothermia
41
ataxia
37
apathy
32
dizziness
30
analgesia
26
ACHE
24
fasciculation
23
respiratory distress
23
anorexia
20
dyspnea
20
exhaustion
18
sleepiness
17
nausea and vomiting
15
abdominal pain
14
overweight
14
cough
13
functional recovery
13
syncope
13
collapse
12
visual hallucination
11
insomnia
11
blurred vision
11
acute stress
10
constipation
10
lethargy
9
skin irritation
9
twitching
9
rhinorrhea
8
more...
Drug
Donepezil
149
Atropine
100
DFP
90
vitamin E
61
THA
58
Scopolamine
37
CSF
32
lysine
28
Aricept
27
Monit
24
Pyridostigmine bromide
23
ascorbate
22
ROS
21
EDR
20
Albumin
17
Pralidoxime
16
Pyridostigmine bromide
16
EPA
16
NADH
15
caffeine
15
Nephron
15
Vitamin E
14
Exelon
14
Galanthamine
14
CTX
13
Dermatol
13
Exelon
12
Leaf
12
Serum albumin
12
Gel
12
Distigmine bromide
10
Glutathione
10
Cardiovasc
9
Mestinon
9
citric acid
9
Clonidine
9
CPT-11
8
PCP
8
Ethanol
8
TAK
8
more...
Enzyme
cholinesterase
12691
acetylcholinesterase
11108
alkaline phosphatase
281
carboxylesterase
267
alanine aminotransferase
250
catalase
222
aspartate aminotransferase
205
lactate dehydrogenase
201
choline acetyltransferase
192
superoxide dismutase
184
monoamine oxidase
163
paraoxonase
142
paraoxonase
126
gamma-glutamyl transpeptidase
119
tyrosinase
118
ATPase
116
glutathione S-transferase
111
peroxidase
92
acid phosphatase
83
creatine kinase
80
lipase
65
glutathione peroxidase
65
trypsin
59
carbonic anhydrase
50
lipoxygenase
46
neuropathy target esterase
43
AST
42
succinate dehydrogenase
41
glutamate dehydrogenase
34
glutamate dehydrogenase
34
glutamate dehydrogenase
34
deaminase
33
chymotrypsin
33
choline oxidase
33
adenosine deaminase
31
leucine aminopeptidase
31
adenosine deaminase
31
glucose-6-phosphate dehydrogenase
30
caspase-3
30
ACS
30
more...
Compound
Dec
848
water
637
Clin
588
phosphate
264
glucose
258
sodium
246
calcium
244
DNA
244
ACh
226
oxygen
213
serine
169
urea
161
hydrogen
156
galanthamine
153
bromide
147
DPPH
147
acetate
146
nitrogen
145
glutamate
144
creatinine
139
methanol
134
iodine
129
GSH
128
GSH
128
PAM
124
potassium
123
OMPA
121
Physostigmine
119
sulfate
112
ethanol
110
ethyl acetate
109
Rivastigmine
101
Atropine
100
Tacrine
98
nitric oxide
98
salt
91
silver
90
ammonium
87
iron
86
Chlorpyrifos
84
more...